中文
相关论文

相关论文: A Federated Learning Benchmark for Drug-Target Int…

200 篇论文

Federated learning holds great potential for enabling large-scale healthcare research and collaboration across multiple centres while ensuring data privacy and security are not compromised. Although numerous recent studies suggest or…

机器学习 · 计算机科学 2025-02-05 Ming Li , Pengcheng Xu , Junjie Hu , Zeyu Tang , Guang Yang

Drug target interaction (DTI) prediction is a foundational task for in silico drug discovery, which is costly and time-consuming due to the need of experimental search over large drug compound space. Recent years have witnessed promising…

定量方法 · 定量生物学 2020-12-10 Kexin Huang , Cao Xiao , Lucas Glass , Jimeng Sun

Federated Learning (FL) enables collaborative model training across distributed clients without sharing raw data, making it ideal for privacy-sensitive applications. However, FL models often suffer performance degradation due to…

Predicting drug-target interactions (DTI) via reliable computational methods is an effective and efficient way to mitigate the enormous costs and time of the drug discovery process. Structure-based drug similarities and sequence-based…

机器学习 · 计算机科学 2021-07-12 Bin Liu , Konstantinos Pliakos , Celine Vens , Grigorios Tsoumakas

Federated learning (FL) addresses privacy concerns in training language models by enabling multiple clients to contribute to the training, without sending their data to others. However, non-IID (identically and independently distributed)…

机器学习 · 计算机科学 2025-01-28 Jong-Ik Park , Carlee Joe-Wong

Drug target interaction (DTI) prediction is a cornerstone of computational drug discovery, enabling rational design, repurposing, and mechanistic insights. While deep learning has advanced DTI modeling, existing approaches primarily rely on…

机器学习 · 计算机科学 2025-11-05 Feng Jiang , Amina Mollaysa , Hehuan Ma , Tommaso Mansi , Junzhou Huang , Mangal Prakash , Rui Liao

Drug combinations can cause adverse drug-drug interactions(DDIs). Identifying specific effects is crucial for developing safer therapies. Previous works on DDI event prediction have typically been limited to using labels of specific events…

生物大分子 · 定量生物学 2024-11-05 Yingying Wang , Yun Xiong , Xixi Wu , Xiangguo Sun , Jiawei Zhang

Federated learning enables many applications benefiting distributed and private datasets of a large number of potential data-holding clients. However, different clients usually have their own particular objectives in terms of the tasks to…

机器学习 · 计算机科学 2022-07-19 Cihat Keçeci , Mohammad Shaqfeh , Hayat Mbayed , Erchin Serpedin

Federated Learning (FL) has emerged as a prominent privacy-preserving technique for enabling use cases like confidential clinical machine learning. FL operates by aggregating models trained by remote devices which owns the data. Thus, FL…

机器学习 · 计算机科学 2024-04-23 Michael Duchesne , Kaiwen Zhang , Chamseddine Talhi

Federated Learning (FL) offers a decentralized paradigm for collaborative model training without direct data sharing, yet it poses unique challenges for Domain Generalization (DG), including strict privacy constraints, non-i.i.d. local…

机器学习 · 计算机科学 2025-01-28 Sunny Gupta , Vinay Sutar , Varunav Singh , Amit Sethi

Federated learning (FL) is a distributed learning paradigm that allows multiple clients to jointly train a shared model while maintaining data privacy. Despite its great potential for domains with strict data privacy requirements, the…

机器学习 · 计算机科学 2025-09-26 Christoph Düsing , Philipp Cimiano

Federated Learning (FL) is a novel machine learning approach that allows the model trainer to access more data samples, by training the model across multiple decentralized data sources, while data access constraints are in place. Such…

Modern machine learning (ML) models have grown to a scale where training them on a single machine becomes impractical. As a result, there is a growing trend to leverage federated learning (FL) techniques to train large ML models in a…

机器学习 · 计算机科学 2024-12-20 Zhanbo Feng , Yuanjie Wang , Jie Li , Fan Yang , Jiong Lou , Tiebin Mi , Robert. C. Qiu , Zhenyu Liao

Federated learning offers a privacy-preserving framework for medical image analysis but exposes the system to adversarial attacks. This paper aims to evaluate the vulnerabilities of federated learning networks in medical image analysis…

密码学与安全 · 计算机科学 2023-10-11 Erfan Darzi , Florian Dubost , N. M. Sijtsema , P. M. A van Ooijen

Since the federated learning, which makes AI learning possible without moving local data around, was introduced by google in 2017 it has been actively studied particularly in the field of medicine. In fact, the idea of machine learning in…

机器学习 · 计算机科学 2021-09-02 Joo Hun Yoo , Hyejun Jeong , Jaehyeok Lee , Tai-Myoung Chung

Federated Learning (FL) enables a group of clients to jointly train a machine learning model with the help of a centralized server. Clients do not need to submit their local data to the server during training, and hence the local training…

机器学习 · 计算机科学 2023-01-10 Liling Zhang , Xinyu Lei , Yichun Shi , Hongyu Huang , Chao Chen

Industrial chemical plants often operate under strict data confidentiality constraints, making centralized data-driven process modeling difficult. Federated learning (FL) provides a promising solution by enabling collaborative model…

机器学习 · 计算机科学 2026-04-30 Teetat Pipattaratonchai , Aueaphum Aueawatthanaphisut

Data privacy is a major concern in industries such as healthcare or finance. The requirement to safeguard privacy is essential to prevent data breaches and misuse, which can have severe consequences for individuals and organisations.…

机器学习 · 计算机科学 2024-12-18 Jose L Salmeron , Irina Arévalo

Federated Learning (FL) has emerged as a significant paradigm for training machine learning models. This is due to its data-privacy-preserving property and its efficient exploitation of distributed computational resources. This is achieved…

机器学习 · 计算机科学 2025-01-22 Mustafa Ghaleb , Mohanad Obeed , Muhamad Felemban , Anas Chaaban , Halim Yanikomeroglu

The effectiveness of clopidogrel, a widely used antiplatelet medication, varies significantly among individuals, necessitating the development of precise predictive models to optimize patient care. In this study, we leverage federated…

机器学习 · 计算机科学 2024-03-07 Samuel Kim , Min Sang Kim