相关论文: A Federated Learning Benchmark for Drug-Target Int…

The advent of Federated Learning has enabled the creation of a high-performing model as if it had been trained on a considerable amount of data. A multitude of participants and a server cooperatively train a model without the need for data…

Federated Learning (FL) is a suitable solution for making use of sensitive data belonging to patients, people, companies, or industries that are obligatory to work under rigid privacy constraints. FL mainly or partially supports data…

Machine learning on large-scale genomic or transcriptomic data is important for many novel health applications. For example, precision medicine tailors medical treatments to patients on the basis of individual biomarkers, cellular and…

Federated learning (FL) has shown promising potential in safeguarding data privacy in healthcare collaborations. While the term "FL" was originally coined by the engineering community, the statistical field has also explored similar…

Drug-drug interactions (DDI) can cause severe adverse drug reactions and pose a major challenge to medication therapy. Recently, informatics-based approaches are emerging for DDI studies. In this paper, we aim to identify key…

Accurate prediction of drug-target binding affinity can accelerate drug discovery by prioritizing promising compounds before costly wet-lab screening. While deep learning has advanced this task, most models fuse ligand and protein…

Federated learning (FL) allows the collaborative training of AI models without needing to share raw data. This capability makes it especially interesting for healthcare applications where patient and data privacy is of utmost concern.…

Fairness has emerged as one of the key challenges in federated learning. In horizontal federated settings, data heterogeneity often leads to substantial performance disparities across clients, raising concerns about equitable model…

This paper provides a comprehensive study of Federated Learning (FL) with an emphasis on components, challenges, applications and FL environment. FL can be applicable in multiple fields and domains in real-life models. in the medical…

Federated Domain Adaptation (FDA) describes the federated learning (FL) setting where source clients and a server work collaboratively to improve the performance of a target client where limited data is available. The domain shift between…

Consider two sets of entities and their members' mutual affinity values, say drug-target affinities (DTA). Drugs and targets are said to interact in their effects on DTAs if drug's effect on it depends on the target. Presence of interaction…

Federated learning (FL) facilitates multiple clients to jointly train a machine learning model without sharing their private data. However, Non-IID data of clients presents a tough challenge for FL. Existing personalized FL approaches rely…

Cross-silo Federated learning (FL) has become a promising tool in machine learning applications for healthcare. It allows hospitals/institutions to train models with sufficient data while the data is kept private. To make sure the FL model…

As the Internet grows in popularity, more and more classification jobs, such as IoT, finance industry and healthcare field, rely on mobile edge computing to advance machine learning. In the medical industry, however, good diagnostic…

Over the years several studies have demonstrated the ability to identify potential drug-drug interactions via data mining from the literature (MEDLINE), electronic health records, public databases (Drugbank), etc. While each one of these…

Federated Learning (FL) is a machine-learning approach enabling collaborative model training across multiple decentralized edge devices that hold local data samples, all without exchanging these samples. This collaborative process occurs…

Drug-drug interaction (DDI) identification is a crucial aspect of pharmacology research. There are many DDI types (hundreds), and they are not evenly distributed with equal chance to occur. Some of the rarely occurred DDI types are often…

Federated learning (FL) enables multiple clients to collaboratively train deep learning models while considering sensitive local datasets' privacy. However, adversaries can manipulate datasets and upload models by injecting triggers for…

Machine learning methods for estimating heterogeneous treatment effects (HTE) facilitate large-scale personalized decision-making across various domains such as healthcare, policy making, education, and more. Current machine learning…

In silico prediction of drug-target interactions (DTI) is significant for drug discovery because it can largely reduce timelines and costs in the drug development process. Specifically, deep learning-based DTI approaches have been shown…