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Brain functional connectome, the collection of interconnected neural circuits along functional networks, is one of the most cutting edge neuroimaging traits, and has a potential to play a mediating role within the effect pathway between an…

统计方法学 · 统计学 2022-01-28 Yize Zhao , Tianqi Chen , Jiachen Cai , Sarah Lichenstein , Marc Potenza , Sarah Yip

In the investigation of any causal mechanisms, such as the brain's causal networks, the assumption of causal sufficiency plays a critical role. Notably, neglecting this assumption can result in significant errors, a fact that is often…

人工智能 · 计算机科学 2024-03-18 Abdolmahdi Bagheri , Mahdi Dehshiri , Babak Nadjar Araabi , Alireza Akhondi Asl

One of the current issues in Brain-Computer Interface is how to deal with noisy Electroencephalography measurements organized as multidimensional datasets. On the other hand, recently, significant advances have been made in multidimensional…

定量方法 · 定量生物学 2018-07-27 Jordi Sole-Casals , Cesar F. Caiafa , Qibin Zhao , Adrzej Cichocki

Causal discovery is central to inferring causal relationships from observational data. In the presence of latent confounding, algorithms such as Fast Causal Inference (FCI) learn a Partial Ancestral Graph (PAG) representing the true model's…

机器学习 · 计算机科学 2025-05-13 Adèle H. Ribeiro , Dominik Heider

Discovering a unique causal structure is difficult due to both inherent identifiability issues, and the consequences of finite data. As such, uncertainty over causal structures, such as those obtained from a Bayesian posterior, are often…

机器学习 · 计算机科学 2025-03-06 Anish Dhir , Matthew Ashman , James Requeima , Mark van der Wilk

Many real-life decision-making situations allow further relevant information to be acquired at a specific cost, for example, in assessing the health status of a patient we may decide to take additional measurements such as diagnostic tests…

Causal discovery is crucial for understanding complex systems and informing decisions. While observational data can uncover causal relationships under certain assumptions, it often falls short, making active interventions necessary. Current…

机器学习 · 计算机科学 2024-06-18 Yuxuan Wang , Mingzhou Liu , Xinwei Sun , Wei Wang , Yizhou Wang

Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

神经元与认知 · 定量生物学 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

Due to the high stakes in medical decision-making, there is a compelling demand for interpretable deep learning methods in medical image analysis. Concept Bottleneck Models (CBM) have emerged as an active interpretable framework…

计算机视觉与模式识别 · 计算机科学 2024-06-28 Yibo Gao , Zheyao Gao , Xin Gao , Yuanye Liu , Bomin Wang , Xiahai Zhuang

Alterations in brain connectivity have been associated with a variety of clinical disorders using functional magnetic resonance imaging (fMRI). We investigated empirically how the number of brain parcels (or scale) impacted the results of a…

定量方法 · 定量生物学 2015-01-28 P. Bellec , Y. Benhajali , F. Carbonell , C. Dansereau , G. Albouy , M. Pelland , C. Craddock , O. Collignon , J. Doyon , E. Stip , P. Orban

The current electroencephalogram (EEG) based deep learning models are typically designed for specific datasets and applications in brain-computer interaction (BCI), limiting the scale of the models and thus diminishing their perceptual…

机器学习 · 计算机科学 2024-06-06 Wei-Bang Jiang , Li-Ming Zhao , Bao-Liang Lu

A Brain Computer Interface (BCI) connects the human brain to the outside world, providing a direct communication channel. Electroencephalography (EEG) signals are commonly used in BCIs to reflect cognitive patterns related to motor function…

机器学习 · 计算机科学 2025-11-19 Abdullah Al Shiam , Md. Khademul Islam Molla , Abu Saleh Musa Miah , Md. Abdus Samad Kamal

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

人工智能 · 计算机科学 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Graph theoretical analyses have become standard tools in modeling functional and anatomical connectivity in the brain. With the advent of connectomics, the primary graphs or networks of interest are structural connectome (derived from DTI…

神经元与认知 · 定量生物学 2022-07-07 Carlo Amodeo , Igor Fortel , Olusola Ajilore , Liang Zhan , Alex Leow , Theja Tulabandhula

Network science has been extensively developed to characterize structural properties of complex systems, including brain networks inferred from neuroimaging data. As a result of the inference process, networks estimated from experimentally…

神经元与认知 · 定量生物学 2017-03-10 Catalina Obando , Fabrizio De Vico Fallani

Genetic association studies for brain connectivity phenotypes have gained prominence due to advances in non-invasive imaging techniques and quantitative genetics. Brain connectivity traits, characterized by network configurations and unique…

统计方法学 · 统计学 2023-05-17 Xinyuan Tian , Yiting Wang , Selena Wang , Yi Zhao , Yize Zhao

The understanding of the convoluted evolution of infant brain networks during the first postnatal year is pivotal for identifying the dynamics of early brain connectivity development. Existing deep learning solutions suffer from three major…

神经元与认知 · 定量生物学 2024-01-09 Michalis Pistos , Gang Li , Weili Lin , Dinggang Shen , Islem Rekik

In functional MRI (fMRI), effective connectivity analysis aims at inferring the causal influences that brain regions exert on one another. A common method for this type of analysis is structural equation modeling (SEM). We here propose a…

定量方法 · 定量生物学 2024-09-10 G. Marrelec , A. Giron

Functional connectivity (FC) between regions of the brain can be assessed by the degree of temporal correlation measured with functional neuroimaging modalities. Based on the fact that these connectivities build a network, graph-based…

计算机视觉与模式识别 · 计算机科学 2021-10-22 Byung-Hoon Kim , Jong Chul Ye , Jae-Jin Kim

Inferring causal structures from experimentation is a central task in many domains. For example, in biology, recent advances allow us to obtain single-cell expression data under multiple interventions such as drugs or gene knockouts.…