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Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…

统计方法学 · 统计学 2025-03-21 Julia Gallini , Zach Baucom , Yorghos Tripodis

Humans can learn concepts or recognize items from just a handful of examples, while machines require many more samples to perform the same task. In this paper, we build a computational model to investigate the possibility of this kind of…

人工智能 · 计算机科学 2016-11-09 Wen-Chieh Fang , Yi-ting Chiang

We develop a data-driven co-segmentation algorithm of passively sensed and self-reported active variables collected through smartphones to identify emotionally stressful states in middle-aged and older patients with mood disorders…

应用统计 · 统计学 2025-04-07 Younghoon Kim , Sumanta Basu , Samprit Banerjee

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

计算机视觉与模式识别 · 计算机科学 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Automated dementia screening enables early detection and intervention, reducing costs to healthcare systems and increasing quality of life for those affected. Depression has shared symptoms with dementia, adding complexity to diagnoses. The…

INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…

We classify very-mild to moderate dementia in patients (CDR ranging from 0 to 2) using a support vector machine classifier acting on dimensionally reduced feature set derived from MRI brain scans of the 416 subjects available in the…

计算机视觉与模式识别 · 计算机科学 2014-06-26 V. A. Miller , S. Erlien , J. Piersol

The proportion of elderly people is increasing worldwide, particularly those living alone in Japan. As elderly people get older, their risks of physical disabilities and health issues increase. To automatically discover these issues at a…

机器学习 · 计算机科学 2024-11-21 Kai Tanaka , Mineichi Kudo , Keigo Kimura , Atsuyoshi Nakamura

Deep learning systems are prone to catastrophic forgetting when learning from a sequence of tasks, as old data from previous tasks is unavailable when learning a new task. To address this, some methods propose replaying data from previous…

计算机视觉与模式识别 · 计算机科学 2025-03-11 Chenyang Wang , Junjun Jiang , Xingyu Hu , Xianming Liu , Xiangyang Ji

Recognizing human activities in a sequence is a challenging area of research in ubiquitous computing. Most approaches use a fixed size sliding window over consecutive samples to extract features---either handcrafted or learned…

计算机视觉与模式识别 · 计算机科学 2017-02-22 Rui Yao , Guosheng Lin , Qinfeng Shi , Damith Ranasinghe

This Signal Processing Grand Challenge (SPGC) targets a difficult automatic prediction problem of societal and medical relevance, namely, the detection of Alzheimer's Dementia (AD). Participants were invited to employ signal processing and…

音频与语音处理 · 电气工程与系统科学 2023-01-16 Saturnino Luz , Fasih Haider , Davida Fromm , Ioulietta Lazarou , Ioannis Kompatsiaris , Brian MacWhinney

Numerous studies attempt to mitigate classification bias caused by class imbalance. However, existing studies have yet to explore the collaborative optimization of imbalanced learning and model training. This constraint hinders further…

机器学习 · 计算机科学 2025-12-30 Chuantao Li , Zhi Li , Jiahao Xu , Jie Li , Sheng Li

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

信号处理 · 电气工程与系统科学 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez

Imbalanced datasets pose significant challenges in areas including neuroscience, cognitive science, and medical diagnostics, where accurately detecting minority classes is essential for robust model performance. This study addresses the…

机器学习 · 计算机科学 2025-06-12 Minheng Xiao

Alzheimer's disease (AD) poses significant global health challenges due to its increasing prevalence and associated societal costs. Early detection and diagnosis of AD are critical for delaying progression and improving patient outcomes.…

计算机视觉与模式识别 · 计算机科学 2026-02-16 Arianna Francesconi , Lazzaro di Biase , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Rosa Sicilia , Valerio Guarrasi

Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…

计算与语言 · 计算机科学 2022-11-09 Loukas Ilias , Dimitris Askounis , John Psarras

Joint models initially dedicated to a single longitudinal marker and a single time-to-event need to be extended to account for the rich longitudinal data of cohort studies. Multiple causes of clinical progression are indeed usually…

应用统计 · 统计学 2016-01-26 Cécile Proust-Lima , Jean-François Dartigues , Hélène Jacqmin-Gadda

INTRODUCTION: Mild cognitive impairment (MCI) is characterized by a decline in cognitive functions beyond typical age and education-related expectations. Since, MCI has been linked to reduced social interactions and increased aimless…

人工智能 · 计算机科学 2024-08-21 Chaitra Hegde , Yashar Kiarashi , Allan I Levey , Amy D Rodriguez , Hyeokhyen Kwon , Gari D Clifford

Current work on speech-based dementia assessment focuses on either feature extraction to predict assessment scales, or on the automation of existing test procedures. Most research uses public data unquestioningly and rarely performs a…

音频与语音处理 · 电气工程与系统科学 2025-08-07 Franziska Braun , Christopher Witzl , Andreas Erzigkeit , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Ensuring the safety and well-being of elderly and vulnerable populations in assisted living environments is a critical concern. Computer vision presents an innovative and powerful approach to predicting health risks through video…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Yixuan Wang , Paul Stynes , Pramod Pathak , Cristina Muntean