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Penalized regression methods, most notably the lasso, are a popular approach to analyzing high-dimensional data. An attractive property of the lasso is that it naturally performs variable selection. An important area of concern, however, is…

统计方法学 · 统计学 2026-05-13 Ryan Miller , Patrick Breheny

Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…

This paper formulates a penalized empirical likelihood (PEL) method for inference on the population mean when the dimension of the observations may grow faster than the sample size. Asymptotic distributions of the PEL ratio statistic is…

统计理论 · 数学 2013-02-28 Soumendra N. Lahiri , Subhodeep Mukhopadhyay

P-splines are penalized B-splines, in which finite order differences in coefficients are typically penalized with an $\ell_2$ norm. P-splines can be used for semiparametric regression and can include random effects to account for…

统计方法学 · 统计学 2018-11-01 Brian D. Segal , Michael R. Elliott , Thomas Braun , Hui Jiang

Causal inference, or counterfactual prediction, is central to decision making in healthcare, policy and social sciences. To de-bias causal estimators with high-dimensional data in observational studies, recent advances suggest the…

机器学习 · 统计学 2020-10-20 Shuxi Zeng , Serge Assaad , Chenyang Tao , Shounak Datta , Lawrence Carin , Fan Li

This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…

应用统计 · 统计学 2019-06-04 Erdem Varol , Aristeidis Sotiras , Ke Zeng , Christos Davatzikos

Selective inference (post-selection inference) is a methodology that has attracted much attention in recent years in the fields of statistics and machine learning. Naive inference based on data that are also used for model selection tends…

统计方法学 · 统计学 2021-11-25 Yoshiyuki Ninomiya , Yuta Umezu , Ichiro Takeuchi

Statistical inference on the explained variation of an outcome by a set of covariates is of particular interest in practice. When the covariates are of moderate to high-dimension and the effects are not sparse, several approaches have been…

统计方法学 · 统计学 2022-01-24 Hua Yun Chen

Differential diagnosis of dementia is challenging due to overlapping symptoms, with structural magnetic resonance imaging (MRI) being the primary method for diagnosis. Despite the clinical value of computer-aided differential diagnosis,…

计算机视觉与模式识别 · 计算机科学 2024-04-10 Yitong Li , Tom Nuno Wolf , Sebastian Pölsterl , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Pretrained language models have been shown to exhibit biases and social stereotypes. Prior work on debiasing these models has largely focused on modifying embedding spaces during pretraining, which is not scalable for large models.…

人工智能 · 计算机科学 2026-02-03 Deep Gandhi , Katyani Singh , Nidhi Hegde

Concept-based explanation approach is a popular model interpertability tool because it expresses the reasons for a model's predictions in terms of concepts that are meaningful for the domain experts. In this work, we study the problem of…

机器学习 · 计算机科学 2021-05-25 Mohammad Taha Bahadori , David E. Heckerman

Frontotemporal dementia and Alzheimer's disease are two common forms of dementia and are easily misdiagnosed as each other due to their similar pattern of clinical symptoms. Differentiating between the two dementia types is crucial for…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Da Ma , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

Target-oriented multimodal sentiment classification seeks to predict sentiment polarity for specific targets from image-text pairs. While existing works achieve competitive performance, they often over-rely on textual content and fail to…

计算与语言 · 计算机科学 2025-09-12 Zhiyue Liu , Fanrong Ma , Xin Ling

In many applications, data can be heterogeneous in the sense of spanning latent groups with different underlying distributions. When predictive models are applied to such data the heterogeneity can affect both predictive performance and…

机器学习 · 统计学 2022-05-04 Thomas Lartigue , Sach Mukherjee

In this paper, we address the inference problem in high-dimensional linear expectile regression. We transform the expectile loss into a weighted-least-squares form and apply a de-biased strategy to establish Wald-type tests for multiple…

统计方法学 · 统计学 2024-01-17 Xiang Li , Yu-Ning Li , Li-Xin Zhang , Jun Zhao

Probabilistic models analyze data by relying on a set of assumptions. Data that exhibit deviations from these assumptions can undermine inference and prediction quality. Robust models offer protection against mismatch between a model's…

机器学习 · 统计学 2018-06-20 Yixin Wang , Alp Kucukelbir , David M. Blei

While deep neural networks (DNNs) are used for prediction, inference on DNN-estimated subject-specific means for categorical or exponential family outcomes remains underexplored. We address this by proposing a DNN estimator under…

机器学习 · 统计学 2026-03-18 Xuran Meng , Yi Li

Existing works on large language model (LLM) decomposition mainly focus on improving performance on downstream tasks, but they ignore the poor parallel inference performance when trying to scale up the model size. To mitigate this important…

计算与语言 · 计算机科学 2026-04-21 You-Liang Huang , Xinhao Huang , Chengxi Liao , Zeyi Wen

Penalization schemes like Lasso or ridge regression are routinely used to regress a response of interest on a high-dimensional set of potential predictors. Despite being decisive, the question of the relative strength of penalization is…

统计方法学 · 统计学 2018-11-08 Britta Velten , Wolfgang Huber

Aging associated brain decline often result in some kind of dementia. Even when this is a complex brain disorder a physical model can be used in order to describe its general behavior. This model is based in first principles. A…

神经元与认知 · 定量生物学 2016-07-22 Oscar Sotolongo-Costa , L. M. Gaggero-Sager , J. T. Becker , F. Maestú , O. Sotolongo-Grau