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The scarcity of high-quality segmentation masks remains a major bottleneck for medical image analysis, particularly in non-contrast CT (NCCT) neuroimaging, where manual annotation is costly and variable. To address this limitation, we…

图像与视频处理 · 电气工程与系统科学 2026-02-12 Lucia Borrego , Vajira Thambawita , Marco Ciuffreda , Ines del Val , Alejandro Dominguez , Josep Munuera

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

定量方法 · 定量生物学 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Current deep learning reconstruction for accelerated cardiac cine MRI suffers from spatial and temporal blurring. We aim to improve image sharpness and motion delineation for cine MRI under high undersampling rates. A spatiotemporal…

图像与视频处理 · 电气工程与系统科学 2024-03-14 Shihan Qiu , Shaoyan Pan , Yikang Liu , Lin Zhao , Jian Xu , Qi Liu , Terrence Chen , Eric Z. Chen , Xiao Chen , Shanhui Sun

The remarkable success of deep learning in recent years has prompted applications in medical image classification and diagnosis tasks. While classification models have demonstrated robustness in classifying simpler datasets like MNIST or…

计算机视觉与模式识别 · 计算机科学 2025-02-26 Sushmita Sarker , Prithul Sarker , George Bebis , Alireza Tavakkoli

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

神经元与认知 · 定量生物学 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

Learning spatial-temporal correspondences in cardiac motion from images is important for understanding the underlying dynamics of cardiac anatomical structures. Many methods explicitly impose smoothness constraints such as the…

图像与视频处理 · 电气工程与系统科学 2022-09-05 Xiaoran Zhang , Chenyu You , Shawn Ahn , Juntang Zhuang , Lawrence Staib , James Duncan

Two-dimensional single-slice abdominal computed tomography (CT) provides a detailed tissue map with high resolution allowing quantitative characterization of relationships between health conditions and aging. However, longitudinal analysis…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Xin Yu , Qi Yang , Yucheng Tang , Riqiang Gao , Shunxing Bao , Leon Y. Cai , Ho Hin Lee , Yuankai Huo , Ann Zenobia Moore , Luigi Ferrucci , Bennett A. Landman

Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

生物大分子 · 定量生物学 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

Real-world problems, for example in climate applications, often require causal reasoning on spatially gridded time series data or data with comparable structure. While the underlying system is often believed to behave similarly at different…

机器学习 · 计算机科学 2026-02-16 Martin Rabel , Jakob Runge

Reconstructing medical images from partial measurements is an important inverse problem in Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). Existing solutions based on machine learning typically train a model to directly map…

图像与视频处理 · 电气工程与系统科学 2022-06-17 Yang Song , Liyue Shen , Lei Xing , Stefano Ermon

Human motion synthesis is an important task in computer graphics and computer vision. While focusing on various conditioning signals such as text, action class, or audio to guide the generation process, most existing methods utilize…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Kebing Xue , Hyewon Seo

Electrical waves in the heart form rotating spiral or scroll waves during life-threatening arrhythmias such as atrial or ventricular fibrillation. The wave dynamics are typically modeled using coupled partial differential equations, which…

医学物理 · 物理学 2024-10-07 Tanish Baranwal , Jan Lebert , Jan Christoph

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

机器学习 · 计算机科学 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Heart rate is one of the most vital health metrics which can be utilized to investigate and gain intuitions into various human physiological and psychological information. Estimating heart rate without the constraints of contact-based…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Mohamed Moustafa , Amr Elrasad , Joseph Lemley , Peter Corcoran

In recent years, increasingly complex computational models are being built to describe physical systems which has led to increased use of surrogate models to reduce computational cost. In problems related to Structural Health Monitoring…

机器学习 · 计算机科学 2024-07-08 Nicholas E. Silionis , Theodora Liangou , Konstantinos N. Anyfantis

We propose a multi-scale lung model to investigate spatio-temporal distributions of ventilation variables. Lung envelope and large airway geometries are derived from CT scans; smaller airways are generated using a physiologically consistent…

组织与器官 · 定量生物学 2026-03-31 Jonathan Stéphano , Michaël Brunengo , Riccardo Di Dio , Thomas Laporte , Benjamin Mauroy

Analyzing temporal developments is crucial for the accurate prognosis of many medical conditions. Temporal changes that occur over short time scales are key to assessing the health of physiological functions, such as the cardiac cycle.…

Generating realistic human geometry animations remains a challenging task, as it requires modeling natural clothing dynamics with fine-grained geometric details under limited data. To address these challenges, we propose two novel designs.…

图形学 · 计算机科学 2025-12-09 Xiangjun Tang , Biao Zhang , Peter Wonka

Generative models, such as GANs and diffusion models, have been used to augment training sets and boost performances in different tasks. We focus on generative models for cell detection instead, i.e., locating and classifying cells in given…

计算机视觉与模式识别 · 计算机科学 2024-09-06 Chen Li , Xiaoling Hu , Shahira Abousamra , Meilong Xu , Chao Chen

Conditional generation models for longitudinal sequences can produce new or modified trajectories given a conditioning input. However, they often lack control over when the condition should take effect (timing) and which variables it should…

机器学习 · 计算机科学 2026-03-10 Michelle M. Li , Kevin Li , Yasha Ektefaie , Ying Jin , Yepeng Huang , Shvat Messica , Tianxi Cai , Marinka Zitnik
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