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Movement disorders, such as Parkinson's disease, affect more than 10 million people worldwide. Gait analysis is a critical step in the diagnosis and rehabilitation of these disorders. Specifically, step length provides valuable insights…

信号处理 · 电气工程与系统科学 2022-05-03 Sizhe An , Yigit Tuncel , Toygun Basaklar , Gokul Krishna Krishnakumar , Ganapati Bhat , Umit Ogras

The stage and severity of Parkinson's disease (PD) is an important factor to consider for taking effective therapeutic decisions. Although the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) provides an…

应用统计 · 统计学 2018-05-30 R. Prashanth , Sumantra Dutta Roy

As our population ages, neurological impairments and degeneration of the musculoskeletal system yield gait abnormalities, which can significantly reduce quality of life. Gait rehabilitative therapy has been widely adopted to help patients…

计算机视觉与模式识别 · 计算机科学 2017-02-02 Ioannis Papavasileiou , Wenlong Zhang , Xin Wang , Jinbo Bi , Li Zhang , Song Han

Parkinson's disease is a common neurological disease, entailing a multitude of motor deficiency symptoms. In this project, we developed a device with an uploaded edge machine learning algorithm that can detect the onset of freezing of gait…

信号处理 · 电气工程与系统科学 2022-11-15 Purnoor Ghuman , Tyama Lyall , Usama Mahboob , Alia Aamir , Xilin Liu

Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Shuai Shao , Yan Wang , Shu Jiang , Shiyuan Zhao , Di Yang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

Modelling the progression of Degenerative Diseases (DD) is essential for detection, prevention, and treatment, yet it remains challenging due to the heterogeneity in disease trajectories among individuals. Factors such as demographics,…

最优化与控制 · 数学 2024-12-19 Alessandro Viani , Boris A Gutman , Emile d'Angremont , Marco Lorenzi

In this paper, we propose a novel deep learning method based on a new Hybrid ConvNet-Transformer architecture to detect and stage Parkinson's disease (PD) from gait data. We adopt a two-step approach by dividing the problem into two…

计算机视觉与模式识别 · 计算机科学 2023-10-27 Safwen Naimi , Wassim Bouachir , Guillaume-Alexandre Bilodeau

Parkinson's disease (PD) is a progressive neurodegenerative disorder that impacts motor functions and speech characteristics This study focuses on differentiating individuals with Parkinson's disease from healthy controls through the…

机器学习 · 计算机科学 2025-01-27 Burak Çelik , Ayhan Akbal

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

应用统计 · 统计学 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

One of the most prevalent complaints of individuals with mid-stage and advanced Parkinson's disease (PD) is the fluctuating response to their medication (i.e., ON state with maximum benefit from medication and OFF state with no benefit from…

计算机视觉与模式识别 · 计算机科学 2018-09-20 Murtadha D. Hssayeni , Michelle A. Burack , M. D. , Joohi Jimenez-Shahed , M. D. , Behnaz Ghoraani , Ph. D

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

定量方法 · 定量生物学 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

Longitudinal voice biomarkers provide a non-invasive source of information for monitoring Parkinson's disease progression, but their statistical analysis is difficult because repeated measurements from the same subject are correlated,…

机器学习 · 统计学 2026-04-28 Ran Tong , Lanruo Wang , Tong Wang , Wei Yan

In this work, we explore various neural network architectures using Magnetic Resonance (MR) T1 images of the brain to identify Parkinson's Disease (PD), which is one of the most common neurodegenerative and movement disorders. We propose…

图像与视频处理 · 电气工程与系统科学 2020-07-27 Tahjid Ashfaque Mostafa , Irene Cheng

In the past few years, there are several researches on Parkinson's disease (PD) recognition using single-photon emission computed tomography (SPECT) images with deep learning (DL) approach. However, the DL model's complexity usually results…

图像与视频处理 · 电气工程与系统科学 2021-05-05 Theerasarn Pianpanit , Sermkiat Lolak , Phattarapong Sawangjai , Thapanun Sudhawiyangkul , Theerawit Wilaiprasitporn

The aim of this study is developing an automatic system for detection of gait-related health problems using Deep Neural Networks (DNNs). The proposed system takes a video of patients as the input and estimates their 3D body pose using a DNN…

计算机视觉与模式识别 · 计算机科学 2020-01-28 Rahil Mehrizi , Xi Peng , Shaoting Zhang , Ruisong Liao , Kang Li

Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…

医学物理 · 物理学 2021-11-25 Simoni Mishra

Human gait can be a predictive factor for detecting pathologies that affect human locomotion according to studies. In addition, it is known that a high investment is demanded in order to raise a traditional clinical infrastructure able to…

信号处理 · 电气工程与系统科学 2021-10-13 T. R. D. Sa , C. M. S. Figueiredo

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

定量方法 · 定量生物学 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that…

计算机视觉与模式识别 · 计算机科学 2020-03-19 Diego L. Guarin , Aidan Dempster , Andrea Bandini , Yana Yunusova , Babak Taati

There is great interest in developing radiological classifiers for diagnosis, staging, and predictive modeling in progressive diseases such as Parkinson's disease (PD), a neurodegenerative disease that is difficult to detect in its early…