相关论文: $^{177}$Lu SPECT Imaging in the Presence of $^{90}…
Purpose: Following the clinical success of 177Lu-based therapies, accurate quantification of 177Lu using radionuclide calibrators (RNCs) and SPECT/CT is gaining importance as prerequisite for accurate treatment delivery and dosimetry.…
The quality of SPECT Bremsstrahlung images of patients treated with Y-90 is poor, mainly because of scattered radiation and collimator septa penetration. To minimize the latter effect, High Energy (HE) or Medium Energy (ME) collimators can…
Purpose: The expansion of radiopharmaceutical therapy (RPT) development demands scalable preclinical dosimetry methods. While PET and SPECT remain the gold standards, their low throughput and high cost limit large-cohort studies. Cherenkov…
Thorium-227-based alpha-particle radiopharmaceutical therapies ({\alpha}-RPTs) are being investigated in several clinical and pre-clinical studies. After administration, Thorium-227 decays to Radium-223, another alpha-particle-emitting…
Purpose: The physical properties of yttrium-90 (90Y) allow for imaging with positron emission tomography/computed tomography (PET/CT). The increased sensitivity of long axial field-of-view (LAFOV) PET/CT scanners possibly allows to overcome…
A custom-built liquid scintillation counter was used for long-term measurements of 90Sr/90Y sources. The detector system is equipped with an automated sample changer and three photomultiplier tubes, which makes the application of the…
Attenuation compensation (AC) is a pre-requisite for reliable quantification and beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT). Typical AC methods require the availability of an attenuation…
A new instrument for spot profile analysis of electron diffraction - SPA-LEED - has been set up. The instrument works either with a transparent phosphor screen for visual inspection of the pattern or in its main mode with a channeltron for…
Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…
Strong quantum-correlated sources are essential but delicate resources for quantum information science and engineering protocols. Decoherence and loss are the two main disruptive processes that lead to the loss of nonclassical behavior in…
Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data,…
Radiative transfer coupled with highly realistic simulations of the solar atmosphere is routinely used to infer the physical properties underlying solar observations. Due to its computational efficiency, the method of short-characteristics…
The electron optics of a 90 degree spherical deflecting analyzer (SDA-90) is investigated with an imaging matrix formalism. As a preanalyzer in the UTA-neutrino experiment, high transmission and reasonable energy resolution are the choices…
SPECT provides a mechanism to perform absorbed-dose quantification tasks for $\alpha$-particle radiopharmaceutical therapies ($\alpha$-RPTs). However, quantitative SPECT for $\alpha$-RPT is challenging due to the low number of detected…
Many optical measurement techniques, such as light scattering from wavelength-scale particles or detecting motion from a surface with an optical lever, encode information in a complex radiation pattern. Extracting all available information…
A high sensitivity Cardiac SPECT system using curved crystals with pinhole collimation was proposed previously (Dey, IEEE TNS 2012, Bhusal et al, Med. Phys. 2019). Here, we hypothesize that a high curvature hemi-ellipsoid detector results…
Measuring the quantum efficiency (QE) map of a photocathode injector typically requires laser scanning, an invasive operation that involves modifying the injector laser focus and rastering the focused laser spot across the photocathode…
Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…
Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (DE-CBCT) imaging has been increasing. However, the image quality of DE-CBCT remains constrained by the Compton scattered X-ray…
This paper describes the qualitative effects of LGS spot elongation and Rayleigh scattering on ALFA wavefront sensor images. An analytical model of Rayleigh scattering and a numerical model of laser plume generation at the altitude of the…