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Graphical lasso is one of the most used estimators for inferring genetic networks. Despite its diffusion, there are several fields in applied research where the limits of detection of modern measurement technologies make the use of this…

统计方法学 · 统计学 2019-11-18 Luigi Augugliaro , Antonino Abbruzzo , Veronica Vinciotti

Gaussian graphical models are recently used in economics to obtain networks of dependence among agents. A widely-used estimator is the Graphical Lasso (GLASSO), which amounts to a maximum likelihood estimation regularized using the…

计量经济学 · 经济学 2017-10-03 Khai X. Chiong , Hyungsik Roger Moon

The Graphical Lasso (GLasso) algorithm is fast and widely used for estimating sparse precision matrices (Friedman et al., 2008). Its central role in the literature of high-dimensional covariance estimation rivals that of Lasso regression…

统计计算 · 统计学 2024-03-20 Aramayis Dallakyan , Mohsen Pourahmadi

We consider the problem of estimating multiple related but distinct graphical models on the basis of a high-dimensional data set with observations that belong to distinct classes. A motivating example occurs in the analysis of gene…

统计方法学 · 统计学 2012-07-12 Patrick Danaher , Pei Wang , Daniela M. Witten

Components of biological systems interact with each other in order to carry out vital cell functions. Such information can be used to improve estimation and inference, and to obtain better insights into the underlying cellular mechanisms.…

机器学习 · 统计学 2010-07-06 Ali Shojaie , George Michailidis

Graphical Gaussian models are popular tools for the estimation of (undirected) gene association networks from microarray data. A key issue when the number of variables greatly exceeds the number of samples is the estimation of the matrix of…

统计方法学 · 统计学 2010-08-13 Nicole Kraemer , Juliane Schaefer , Anne-Laure Boulesteix

Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with…

机器学习 · 统计学 2008-11-16 Seyoung Kim , Kyung-Ah Sohn , Eric P. Xing

The graphical lasso \citep{FHT2007a} is an algorithm for learning the structure in an undirected Gaussian graphical model, using $\ell_1$ regularization to control the number of zeros in the precision matrix ${\B\Theta}={\B\Sigma}^{-1}$…

机器学习 · 统计学 2012-08-09 Rahul Mazumder , Trevor Hastie

The graphical Lasso (GLASSO) is a widely used algorithm for learning high-dimensional undirected Gaussian graphical models (GGM). Given i.i.d. observations from a multivariate normal distribution, GLASSO estimates the precision matrix by…

统计方法学 · 统计学 2026-01-15 Ha Nguyen , Sumanta Basu

We consider the task of estimating a Gaussian graphical model in the high-dimensional setting. The graphical lasso, which involves maximizing the Gaussian log likelihood subject to an l1 penalty, is a well-studied approach for this task. We…

机器学习 · 统计学 2013-07-23 Kean Ming Tan , Daniela Witten , Ali Shojaie

Graphical Lasso (GL) is a popular method for learning the structure of an undirected graphical model, which is based on an $l_1$ regularization technique. The objective of this paper is to compare the computationally-heavy GL technique with…

机器学习 · 统计学 2019-07-02 Salar Fattahi , Somayeh Sojoudi

The regression of multiple inter-connected sequence data is a problem in various disciplines. Formally, we name the regression problem of multiple inter-connected data entities as the "dynamic network regression" in this paper. Within the…

机器学习 · 计算机科学 2020-10-19 Yixin Chen , Lin Meng , Jiawei Zhang

This work proposes an adaptive trace lasso regularized L1-norm based graph cut method for dimensionality reduction of Hyperspectral images, called as `Trace Lasso-L1 Graph Cut' (TL-L1GC). The underlying idea of this method is to generate…

计算机视觉与模式识别 · 计算机科学 2018-07-30 Ramanarayan Mohanty , S L Happy , Nilesh Suthar , Aurobinda Routray

We propose an L1-penalized algorithm for fitting high-dimensional generalized linear mixed models. Generalized linear mixed models (GLMMs) can be viewed as an extension of generalized linear models for clustered observations. This…

统计计算 · 统计学 2014-06-03 Jürg Schelldorfer , Lukas Meier , Peter Bühlmann

Accurate gene regulatory networks can be used to explain the emergence of different phenotypes, disease mechanisms, and other biological functions. Many methods have been proposed to infer networks from gene expression data but have been…

定量方法 · 定量生物学 2018-12-11 Phan Nguyen , Rosemary Braun

Graph model is emerging as a very effective tool for learning the complex structures and relationships hidden in data. Generally, the critical purpose of graph-oriented learning algorithms is to construct an informative graph for image…

计算机视觉与模式识别 · 计算机科学 2016-12-21 Qingshan Liu , Yubao Sun , Cantian Wang , Tongliang Liu , Dacheng Tao

This work addresses the problem of graph learning from data following a Gaussian Graphical Model (GGM) with a time-varying mean. Graphical Lasso (GL), the standard method for estimating sparse precision matrices, assumes that the observed…

机器学习 · 计算机科学 2025-03-26 Samuel Rey , Ernesto Curbelo , Luca Martino , Fernando Llorente , Antonio G. Marques

The Gaussian graphical model is a widely used tool for learning gene regulatory networks with high-dimensional gene expression data. Most existing methods for Gaussian graphical models assume that the data are homogeneous, i.e., all samples…

统计方法学 · 统计学 2018-05-08 Bochao Jia , Faming Liang

Learning interpretable multimodal representations inherently relies on uncovering the conditional dependencies between heterogeneous features. However, sparse graph estimation techniques, such as Graphical Lasso (GLasso), to…

计算机视觉与模式识别 · 计算机科学 2026-04-07 Fei Wang , Yutong Zhang , Xiong Wang

Gaussian Graphical Models (GGMs) are widely used in high-dimensional data analysis to synthesize the interaction between variables. In many applications, such as genomics or image analysis, graphical models rely on sparsity and clustering…

机器学习 · 统计学 2026-03-25 Do Edmond Sanou , Christophe Ambroise , Geneviève Robin
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