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Signaling events in eukaryotic cells are often guided by a scaffolding protein. Scaffold proteins assemble multiple proteins in a spatially localized signaling complex and exert numerous physical effects on signaling pathways. To study…

亚细胞过程 · 定量生物学 2009-11-13 Jason W. Locasale

Diffusion models are learning pattern-learning systems to model and sample from data distributions with three functional components namely the forward process, the reverse process, and the sampling process. The components of diffusion…

机器学习 · 计算机科学 2025-06-02 Ziyi Chang , George Alex Koulieris , Hyung Jin Chang , Hubert P. H. Shum

The Hopfield model provides a mathematically idealized yet insightful framework for understanding the mechanisms of memory storage and retrieval in the human brain. This model has inspired four decades of extensive research on learning and…

神经元与认知 · 定量生物学 2025-05-14 Simone Betteti , Giacomo Baggio , Francesco Bullo , Sandro Zampieri

Learning from a large corpus of data, pre-trained models have achieved impressive progress nowadays. As popular generative pre-training, diffusion models capture both low-level visual knowledge and high-level semantic relations. In this…

计算机视觉与模式识别 · 计算机科学 2023-03-20 Chaofan Ma , Yuhuan Yang , Chen Ju , Fei Zhang , Jinxiang Liu , Yu Wang , Ya Zhang , Yanfeng Wang

Diffusion describes the motion of microscopic entities from regions of high concentration to regions of low concentration. In multiplex networks, flows can occur both within and across layers, and super-diffusion, a regime where the time…

物理与社会 · 物理学 2019-04-02 Giulia Cencetti , Federico Battiston

Much research has been done on studying the diffusion of ideas or technologies on social networks including the \textit{Influence Maximization} problem and many of its variations. Here, we investigate a type of inverse problem. Given a…

社会与信息网络 · 计算机科学 2014-04-28 Georgios Askalidis , Randall A. Berry , Vijay G. Subramanian

A new upscaling procedure that provides 1D representations of 2D mixing-limited reactive transport systems is developed and applied. A key complication with upscaled models in this setting is that the procedure must differentiate between…

流体动力学 · 物理学 2022-10-05 Ricardo H. Deucher , Louis J. Durlofsky

We consider a stochastically perturbed reaction diffusion equation in a bounded interval, with boundary conditions imposing the two stable phases at the endpoints. We investigate the asymptotic behavior of the front separating the two…

数学物理 · 物理学 2016-02-11 L. Bertini , S. Brassesco , P. Buttà

The task of learning a diffusion-based neural sampler for drawing samples from an unnormalized target distribution can be viewed as a stochastic optimal control problem on path measures. However, the training of neural samplers can be…

机器学习 · 计算机科学 2026-05-20 Wei Guo , Jaemoo Choi , Yuchen Zhu , Molei Tao , Yongxin Chen

We introduce a new technique called Drapes to enhance the sensitivity in searches for new physics at the LHC. By training diffusion models on side-band data, we show how background templates for the signal region can be generated either…

数据分析、统计与概率 · 物理学 2023-12-20 Debajyoti Sengupta , Matthew Leigh , John Andrew Raine , Samuel Klein , Tobias Golling

Proteins play a critical role in carrying out biological functions, and their 3D structures are essential in determining their functions. Accurately predicting the conformation of protein side-chains given their backbones is important for…

定量方法 · 定量生物学 2024-02-19 Yangtian Zhang , Zuobai Zhang , Bozitao Zhong , Sanchit Misra , Jian Tang

In this paper a lattice model for diffusional transport of particles in the interphase cell nucleus is proposed. Dense networks of chromatin fibers are created by three different methods: randomly distributed, non-interconnected obstacles,…

生物物理 · 物理学 2009-11-13 Annika Wedemeier , Holger Merlitz , Chen-Xu Wu , Jörg Langowski

We present a cascaded diffusion model based on a part-level implicit 3D representation. Our model achieves state-of-the-art generation quality and also enables part-level shape editing and manipulation without any additional training in…

计算机视觉与模式识别 · 计算机科学 2024-03-21 Juil Koo , Seungwoo Yoo , Minh Hieu Nguyen , Minhyuk Sung

We discuss the hydrodynamic collective effects due to active protein molecules that are immersed in lipid bilayer membranes and modeled as stochastic force dipoles. We specifically take into account the presence of the bulk solvent which…

软凝聚态物质 · 物理学 2017-05-24 Yuto Hosaka , Kento Yasuda , Ryuichi Okamoto , Shigeyuki Komura

Diffusion models offer stable training and state-of-the-art performance for deep generative modeling tasks. Here, we consider their use in the context of multivariate subsurface modeling and probabilistic inversion. We first demonstrate…

计算机视觉与模式识别 · 计算机科学 2026-01-28 Roberto Miele , Niklas Linde

The interaction of fluid membranes with a scaffold, which can be a planar surface or a more complex structure, is intrinsic to a number of systems - from artificial supported bilayers and vesicles to cellular membranes. In principle, these…

软凝聚态物质 · 物理学 2014-05-07 Daniel Schmidt , Cornelia Monzel , Timo Bihr , Rudolf Merkel , Udo Seifert , Kheya Sengupta , Ana-Sunčana Smith

In materials science, microstructures and their associated extrinsic properties are critical for engineering advanced structural and functional materials, yet their robust reconstruction and generation remain significant challenges. In this…

材料科学 · 物理学 2024-10-01 Yixuan Zhang , Teng Long , Hongbin Zhang

Diffusion models have demonstrated exceptional performances in various fields of generative modeling, but suffer from slow sampling speed due to their iterative nature. While this issue is being addressed in continuous domains, discrete…

机器学习 · 计算机科学 2025-05-12 Satoshi Hayakawa , Yuhta Takida , Masaaki Imaizumi , Hiromi Wakaki , Yuki Mitsufuji

Many visual scenes can be described as compositions of latent factors. Effective recognition, reasoning, and editing often require not only forming such compositional representations, but also solving the decomposition problem. One popular…

计算机视觉与模式识别 · 计算机科学 2026-02-11 Calvin Yeung , Ali Zakeri , Zhuowen Zou , Mohsen Imani

We first review traditional approaches to memory storage and formation, drawing on the literature of quantitative neuroscience as well as statistical physics. These have generally focused on the fast dynamics of neurons; however, there is…

神经元与认知 · 定量生物学 2018-07-24 Anita Mehta