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Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

信号处理 · 电气工程与系统科学 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks…

机器学习 · 计算机科学 2019-11-26 James Wingate , Ilianna Kollia , Luc Bidaut , Stefanos Kollias

Anatomy evaluation is crucial for understanding the physiological state, diagnosing abnormalities, and guiding medical interventions. Statistical shape modeling (SSM) is vital in this process. By enabling the extraction of quantitative…

计算机视觉与模式识别 · 计算机科学 2025-02-12 Krithika Iyer , Mokshagna Sai Teja Karanam , Shireen Elhabian

This paper describes a new model for an artificial neural network processing unit or neuron. It is slightly different to a traditional feedforward network by the fact that it favours a mechanism of trying to match the wave-like 'shape' of…

神经与进化计算 · 计算机科学 2014-03-06 Kieran Greer

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

机器学习 · 计算机科学 2021-01-13 Alexander Lavin

Alzheimer's disease (AD) is characterized by complex and largely unknown progression dynamics affecting the brain's morphology. Although the disease evolution spans decades, to date we cannot rely on long-term data to model the pathological…

应用统计 · 统计学 2019-08-14 Clement Abi Nader , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

计算机视觉与模式识别 · 计算机科学 2025-01-13 Aswini Kumar Patra , Soraisham Elizabeth Devi , Tejashwini Gajurel

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Particle-based shape modeling (PSM) is a popular approach to automatically quantify shape variability in populations of anatomies. The PSM family of methods employs optimization to automatically populate a dense set of corresponding…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Hong Xu , Shireen Y. Elhabian

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

定量方法 · 定量生物学 2018-08-07 Mayssa Soussia , Islem Rekik

Efficient and fast reconstruction of anatomical structures plays a crucial role in clinical practice. Minimizing retrieval and processing times not only potentially enhances swift response and decision-making in critical scenarios but also…

Statistical Shape Modeling (SSM) effectively analyzes anatomical variations within populations but is limited by the need for manual localization and segmentation, which relies on scarce medical expertise. Recent advances in deep learning…

计算机视觉与模式识别 · 计算机科学 2024-07-10 Janmesh Ukey , Tushar Kataria , Shireen Y. Elhabian

Spontaneous brain activity generically displays transient spatiotemporal coherent structures, which can selectively be affected in various neurological and psychiatric pathologies. Here we model the full brain's electroencephalographic…

神经元与认知 · 定量生物学 2025-02-25 Annalisa Caligiuri , David Papo , Görsev Yener , Bahar Güntekin , Tobias Galla , Lucas Lacasa , Massimiliano Zanin

Early diagnosis of Alzheimer's disease plays a key role in understanding the degree of the patient's mental decline and determining preventive therapies. In this study, we introduce WaveletBrain, a novel representation of the white and gray…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Majid Masoumi , Matthew Toews , Herve Lombaert

Normative modeling has emerged as a pivotal approach for characterizing heterogeneity and individual variance in neurodegenerative diseases, notably Alzheimer's disease(AD). One of the challenges of cortical normative modeling is the…

图像与视频处理 · 电气工程与系统科学 2026-03-13 Jianwei Zhang , Yonggang Shi

Congenital heart disease (CHD) is a relatively rare disease that affects patients at birth and results in extremely heterogeneous anatomical and functional defects. 12-lead ECG signal is routinely collected in CHD patients because it…

信号处理 · 电气工程与系统科学 2024-10-28 Muhammet Alkan , Gruschen Veldtman , Fani Deligianni

In this paper, we propose RiemannianFlow, a deep generative model that allows robots to learn complex and stable skills evolving on Riemannian manifolds. Examples of Riemannian data in robotics include stiffness (symmetric and positive…

机器人学 · 计算机科学 2023-09-27 Weitao Wang , Matteo Saveriano , Fares J. Abu-Dakka

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

图像与视频处理 · 电气工程与系统科学 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

Early detection of Alzheimer disease is crucial for deploying interventions and slowing the disease progression. A lot of machine learning and deep learning algorithms have been explored in the past decade with the aim of building an…

图像与视频处理 · 电气工程与系统科学 2022-09-26 Narotam Singh , Patteshwari. D , Neha Soni , Amita Kapoor

This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural…

机器学习 · 计算机科学 2025-08-22 Jiacheng Hu , Bo Zhang , Ting Xu , Haifeng Yang , Min Gao