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DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced…

信息论 · 计算机科学 2024-03-13 Daniella Bar-Lev , Itai Orr , Omer Sabary , Tuvi Etzion , Eitan Yaakobi

DNA is a promising medium for digital information storage for its exceptional density and durability. While prior studies advanced coding theory, workflow design, and simulation tools, challenges such as synthesis costs, sequencing errors,…

新兴技术 · 计算机科学 2025-10-06 Rakesh Thakur , Lavanya Singh , Yashika , Manomay Bundawala , Aruna Kumar

We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…

Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in…

机器学习 · 计算机科学 2021-10-22 David Buterez

Digital information can be encoded in the building-block sequence of macro-molecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive.…

新兴技术 · 计算机科学 2017-09-14 Masud Mansuripur , Pramod Khulbe

DNA data storage offers a high-density, long-term alternative to traditional storage systems, addressing the exponential growth of digital data. Composite DNA extends this paradigm by leveraging mixtures of nucleotides to increase storage…

信息论 · 计算机科学 2026-02-13 Busra Tegin , Tolga M Duman

DNA has been discussed as a potential medium for data storage. Potentially it could be denser, could consume less energy, and could be more durable than conventional storage media such as hard drives, solid-state storage, and optical media.…

新兴技术 · 计算机科学 2023-07-04 Arnav Solanki , Zak Griffin , Purab Ranjan Sutradhar , Amlan Ganguly , Marc D. Riedel

We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing…

信息论 · 计算机科学 2015-05-12 S. M. Hossein Tabatabaei Yazdi , Yongbo Yuan , Jian Ma , Huimin Zhao , Olgica Milenkovic

Because of DNA appealing features as perfect material, including minuscule size, defined structural repeat and rigidity, programmable DNA-mediated processing is a promising computing paradigm, which employs DNAs as information storing and…

生物物理 · 物理学 2015-08-17 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong , Fangwei Shao , Kee Jin Lee

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and trade-offs of DNA-based storage systems by introducing a new channel model, which we…

信息论 · 计算机科学 2020-01-20 Ilan Shomorony , Reinhard Heckel

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

新兴技术 · 计算机科学 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

The emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of…

基因组学 · 定量生物学 2025-01-28 Hadas Abraham , Barak Gahtan , Adir Kobovich , Orian Leitersdorf , Alex M. Bronstein , Eitan Yaakobi

Since the birth of computer and networks, fuelled by pervasive computing and ubiquitous connectivity, the amount of data stored and transmitted has exponentially grown through the years. Due to this demand, new solutions for storing data…

A simple DNA-based data storage scheme is demonstrated in which information is written using "addressing" oligonucleotides. In contrast to other methods that allow arbitrary code to be stored, the resulting DNA is suitable for downstream…

新兴技术 · 计算机科学 2017-11-15 Gary M. Skinner , Koen Visscher , Masud Mansuripur

Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…

硬件体系结构 · 计算机科学 2011-11-09 Fei Su , Krishnendu Chakrabarty

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

机器学习 · 计算机科学 2022-03-21 Xavier Pic , Marc Antonini

DNA is emerging as an increasingly attractive medium for data storage due to a number of important and unique advantages it offers, most notably the unprecedented durability and density. While the technology is evolving rapidly, the…

新兴技术 · 计算机科学 2022-05-03 Dehui Lin , Yasamin Tabatabaee , Yash Pote , Djordje Jevdjic

DNA has immense potential as an emerging data storage medium. The principle of DNA storage is the conversion and flow of digital information between binary code stream, quaternary base, and actual DNA fragments. This process will inevitably…

信息检索 · 计算机科学 2022-10-21 Yun Qin , Fei Zhu , Bo Xi

As a possible implementation of data storage using DNA, multiple strands of DNA are stored in a liquid container so that, in the future, they can be read by an array of DNA readers in parallel. These readers will sample the strands with…

信息论 · 计算机科学 2024-09-04 Hsin-Po Wang , Venkatesan Guruswami

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

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