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Multivariate conformal prediction requires nonconformity scores that compress residual vectors into scalars while preserving certain implicit geometric structure of the residual distribution. We introduce a Multivariate Kernel Score (MKS)…

机器学习 · 统计学 2026-04-24 Louis Meyer , Wenkai Xu

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

计算机视觉与模式识别 · 计算机科学 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Deep learning (DL) methods for white matter lesion (WML) segmentation in MRI suffer a reduction in performance when applied on data from a scanner or centre that is out-of-distribution (OOD) from the training data. This is critical for…

图像与视频处理 · 电气工程与系统科学 2023-07-11 Abdollah Ghazvanchahi , Pejman Jahbedar Maralani , Alan R. Moody , April Khademi

Bone marrow lesions (BMLs) are critical indicators of knee osteoarthritis (OA). Since they often appear as small, irregular structures with indistinguishable edges in knee magnetic resonance images (MRIs), effective detection of BMLs in MRI…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Shihua Qin , Ming Zhang , Juan Shan , Taehoon Shin , Jonghye Woo , Fangxu Xing

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

图像与视频处理 · 电气工程与系统科学 2023-08-21 Vanessa Gonzalez Duque , Leonhard Zirus , Yordanka Velikova , Nassir Navab , Diana Mateus

Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

机器学习 · 计算机科学 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

计算机视觉与模式识别 · 计算机科学 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

In the last few decades, significant achievements have been attained in predicting where humans look at images through different computational models. However, how to determine contributions of different visual features to overall saliency…

计算机视觉与模式识别 · 计算机科学 2013-07-23 Yasin Kavak , Erkut Erdem , Aykut Erdem

While multiple studies have explored the relation between inter-rater variability and deep learning model uncertainty in medical segmentation tasks, little is known about the impact of individual rater style. This study quantifies rater…

计算机视觉与模式识别 · 计算机科学 2021-05-06 Olivier Vincent , Charley Gros , Julien Cohen-Adad

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Uncertainty estimation in deep learning has become a leading research field in medical image analysis due to the need for safe utilisation of AI algorithms in clinical practice. Most approaches for uncertainty estimation require sampling…

图像与视频处理 · 电气工程与系统科学 2022-04-12 Kaisar Kushibar , Víctor Manuel Campello , Lidia Garrucho Moras , Akis Linardos , Petia Radeva , Karim Lekadir

Longitudinal lesion analysis is crucial for oncological care, yet automated tools often struggle with temporal consistency. While universal lesion segmentation models have advanced, they are typically designed for single time points. This…

图像与视频处理 · 电气工程与系统科学 2025-07-28 Niels Rocholl , Ewoud Smit , Mathias Prokop , Alessa Hering

How similar are two images? In computational pathology, where Whole Slide Images (WSIs) of digitally scanned tissue samples from patients can be multi-gigapixels in size, determination of degree of similarity between two WSIs is a…

图像与视频处理 · 电气工程与系统科学 2023-01-24 Piotr Keller , Muhammad Dawood , Fayyaz ul Amir Afsar Minhas

Despite impressive state-of-the-art performance on a wide variety of machine learning tasks, deep learning methods can produce over-confident predictions, particularly with limited training data. Therefore, quantifying uncertainty is…

机器学习 · 计算机科学 2022-04-27 Haleh Akrami , Anand Joshi , Sergul Aydore , Richard Leahy

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

We propose Region-wise (RW) loss for biomedical image segmentation. Region-wise loss is versatile, can simultaneously account for class imbalance and pixel importance, and it can be easily implemented as the pixel-wise multiplication…

图像与视频处理 · 电气工程与系统科学 2022-03-30 Juan Miguel Valverde , Jussi Tohka

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…

图像与视频处理 · 电气工程与系统科学 2020-09-29 Stefan Denner , Ashkan Khakzar , Moiz Sajid , Mahdi Saleh , Ziga Spiclin , Seong Tae Kim , Nassir Navab

Report-supervised (RSuper) learning seeks to alleviate the need for dense tumor voxel labels with constraints derived from radiology reports (e.g., volumes, counts, sizes, locations). In MRI studies of brain tumors, however, we often…

图像与视频处理 · 电气工程与系统科学 2026-02-25 Yubin Ge , Yongsong Huang , Xiaofeng Liu

Medical brain image analysis is a necessary step in Computer Assisted /Aided Diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases.…

图像与视频处理 · 电气工程与系统科学 2021-01-15 Darwin Castillo , Vasudevan Lakshminarayanan , Maria J. Rodriguez-Alvarez