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Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…

定量方法 · 定量生物学 2024-03-05 Richard G. Carson , Alexander Leemans

Current theories hold that brain function is highly related to long-range physical connections through axonal bundles, namely extrinsic connectiv-ity. However, obtaining a groupwise cortical parcellation based on extrinsic connectivity…

应用统计 · 统计学 2017-01-06 Guillermo Gallardo , William Wells , Rachid Deriche , Demian Wassermann

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Diffusion MRI (dMRI) streamline tractography, the gold standard for in vivo estimation of brain white matter (WM) pathways, has long been considered indicative of macroscopic relationships with WM microstructure. However, recent advances in…

图像与视频处理 · 电气工程与系统科学 2024-03-29 Tian Yu , Yunhe Li , Michael E. Kim , Chenyu Gao , Qi Yang , Leon Y. Cai , Susane M. Resnick , Lori L. Beason-Held , Daniel C. Moyer , Kurt G. Schilling , Bennett A. Landman

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Directionality is a fundamental feature of network connections. Most structural brain networks are intrinsically directed because of the nature of chemical synapses, which comprise most neuronal connections. Due to limitations of…

神经元与认知 · 定量生物学 2018-01-19 Penelope Kale , Andrew Zalesky , Leonardo L. Gollo

Graph deep learning models, a class of AI-driven approaches employing a message aggregation mechanism, have gained popularity for analyzing the functional brain connectome in neuroimaging. However, their actual effectiveness remains…

神经与进化计算 · 计算机科学 2026-02-10 Keqi Han , Yao Su , Lifang He , Liang Zhan , Sergey Plis , Vince Calhoun , Carl Yang

In the high-dimensional landscape, addressing the challenges of covariance regression with high-dimensional covariates has posed difficulties for conventional methodologies. This paper addresses these hurdles by presenting a novel approach…

统计方法学 · 统计学 2024-04-11 Yuheng He , Changliang Zou , Yi Zhao

In the present work, we use information theory to understand the empirical convergence rate of tractography, a widely-used approach to reconstruct anatomical fiber pathways in the living brain. Based on diffusion MRI data, tractography is…

定量方法 · 定量生物学 2018-06-13 Daniel Moyer , Paul M. Thompson , Greg Ver Steeg

Representation of brain network interactions is fundamental to the translation of neural structure to brain function. As such, methodologies for mapping neural interactions into structural models, i.e., inference of functional connectome…

神经元与认知 · 定量生物学 2022-03-18 Rahul Biswas , Eli Shlizerman

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

图像与视频处理 · 电气工程与系统科学 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

神经元与认知 · 定量生物学 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Connections of the living human brain, on a macroscopic scale, can be mapped by a diffusion MR imaging based workflow. Since the same anatomic regions can be corresponded between distinct brains, one can compare the presence or the absence…

神经元与认知 · 定量生物学 2016-02-16 Balázs Szalkai , Csaba Kerepesi , Bálint Varga , Vince Grolmusz

In this study we adopt predictive modelling to identify simultaneously commonalities and differences in multi-modal brain networks acquired within subjects. Typically, predictive modelling of functional connectomes from structural…

神经元与认知 · 定量生物学 2019-11-06 Fani Deligianni , Jonathan D. Clayden , Guang-Zhong Yang

Brain segmentation at different levels is generally represented as hierarchical trees. Brain regional atrophy at specific levels was found to be marginally associated with Alzheimer's disease outcomes. In this study, we propose an L1-type…

应用统计 · 统计学 2021-04-02 Yi Zhao , Bingkai Wang , Chin-Fu Liu , Andreia V. Faria , Michael I. Miller , Brian S. Caffo , Xi Luo

One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open…

神经元与认知 · 定量生物学 2018-02-22 Enrico Amico , Joaquín Goñi

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial method for white matter (WM) parcellation to enable analysis of brains structural connectivity in health and disease. Current fiber clustering strategies primarily use…

图像与视频处理 · 电气工程与系统科学 2025-11-04 Bocheng Guo , Jin Wang , Yijie Li , Junyi Wang , Mingyu Gao , Puming Feng , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

计算机视觉与模式识别 · 计算机科学 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

We propose a novel matrix autoencoder to map functional connectomes from resting state fMRI (rs-fMRI) to structural connectomes from Diffusion Tensor Imaging (DTI), as guided by subject-level phenotypic measures. Our specialized autoencoder…

Brain decoding that classifies cognitive states using the functional fluctuations of the brain can provide insightful information for understanding the brain mechanisms of cognitive functions. Among the common procedures of decoding the…

人机交互 · 计算机科学 2024-07-12 Jianfei Zhu , Baichun Wei , Jiaru Tian , Feng Jiang , Chunzhi Yi