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Quantifying causal effects of exposures on outcomes, such as a treatment and a disease respectively, is a crucial issue in medical science for the administration of effective therapies. Importantly, any related causal analysis should…

统计方法学 · 统计学 2024-09-04 Federico Castelletti , Laura Ferrini

Graph Neural Networks (GNNs) have shown remarkable effectiveness in capturing abundant information in graph-structured data. However, the black-box nature of GNNs hinders users from understanding and trusting the models, thus leading to…

机器学习 · 计算机科学 2022-07-25 Jiaxuan Xie , Yezi Liu , Yanning Shen

Discovering causal structures from data is a challenging inference problem of fundamental importance in all areas of science. The appealing properties of neural networks have recently led to a surge of interest in differentiable neural…

Granger-Geweke causality (GGC) is a powerful and popular method for identifying directed functional (`causal') connectivity in neuroscience. In a recent paper, Stokes and Purdon [1] raise several concerns about its use. They make two…

统计方法学 · 统计学 2018-02-07 Lionel Barnett , Adam B. Barrett , Anil K. Seth

The advent of single-cell technology has significantly improved our understanding of cellular states and subpopulations in various tissues under normal and diseased conditions by employing data-driven approaches such as clustering and…

Directed acyclic graph (DAG) models, also called Bayesian networks, impose conditional independence constraints on a multivariate probability distribution, and are widely used in probabilistic reasoning, machine learning and causal…

统计理论 · 数学 2022-12-20 Robin J. Evans

This paper addresses the problem of estimating causal directed acyclic graphs in linear non-Gaussian acyclic models with latent confounders (LvLiNGAM). Existing methods assume mutually independent latent confounders or cannot properly…

机器学习 · 计算机科学 2025-10-17 Ming Cai , Penggang Gao , Hisayuki Hara

Since interactions in neural systems occur across multiple temporal scales, it is likely that information flow will exhibit a multiscale structure, thus requiring a multiscale generalization of classical temporal precedence causality…

定量方法 · 定量生物学 2017-07-13 Sebastiano Stramaglia , Iege Bassez , Luca Faes , Daniele Marinazzo

We analyze by means of Granger causality the effect of synergy and redundancy in the inference (from time series data) of the information flow between subsystems of a complex network. Whilst we show that fully conditioned Granger causality…

定量方法 · 定量生物学 2015-06-19 Sebastiano Stramaglia , Jesus M. Cortes , Daniele Marinazzo

Discovering causal structures from multivariate time series is a key problem because interactions span across multiple lags and possibly involve instantaneous dependencies. Additionally, the search space of the dynamic graphs is…

机器学习 · 计算机科学 2026-05-19 Sourajit Das , Dibyajyoti Chakraborty , Romit Maulik

Identifying causal relations among simultaneously acquired signals is an important problem in multivariate time series analysis. For linear stochastic systems Granger proposed a simple procedure called the Granger causality to detect such…

混沌动力学 · 物理学 2009-11-10 Yonghong Chen , Govindan Rangarajan , Jianfeng Feng , Mingzhou Ding

Link prediction (inferring missing or future connections between nodes in a graph) is a fundamental problem in network science with widespread applications in, e.g., biological systems, recommender systems, finance and cybersecurity. The…

机器学习 · 计算机科学 2026-05-12 Riccardo Porcedda , Francesca Chiaromonte , Fabrizio Lillo , Andrea Vandin

Accurately predicting drug-target interactions (DTIs) is pivotal for advancing drug discovery and target validation techniques. While machine learning approaches including those that are based on Graph Neural Networks (GNN) have achieved…

机器学习 · 计算机科学 2025-09-30 Yuehua Song , Yong Gao

There is increasing interest in identifying changes in the underlying states of brain networks. The availability of large scale neuroimaging data creates a strong need to develop fast, scalable methods for detecting and localizing in time…

统计方法学 · 统计学 2022-01-11 Peiliang Bai , Abolfazl Safikhani , George Michailidis

Directed acyclic graphs (DAGs) serve as crucial data representations in domains such as hardware synthesis and compiler/program optimization for computing systems. DAG generative models facilitate the creation of synthetic DAGs, which can…

机器学习 · 计算机科学 2025-03-04 Mufei Li , Viraj Shitole , Eli Chien , Changhai Man , Zhaodong Wang , Srinivas Sridharan , Ying Zhang , Tushar Krishna , Pan Li

Ordinal variables, such as on the Likert scale, are common in applied research. Yet, existing methods for causal inference tend to target nominal or continuous data. When applied to ordinal data, this fails to account for the inherent…

统计方法学 · 统计学 2025-02-26 Martina Scauda , Jack Kuipers , Giusi Moffa

We give a selective review of some recent developments in causal inference, intended for researchers who are not familiar with graphical models and causality, and with a focus on methods that are applicable to large data sets. We mainly…

统计方法学 · 统计学 2015-06-26 Marloes H. Maathuis , Preetam Nandy

Graph-based causal discovery methods aim to capture conditional independencies consistent with the observed data and differentiate causal relationships from indirect or induced ones. Successful construction of graphical models of data…

机器学习 · 统计学 2021-01-08 Boris Hayete , Fred Gruber , Anna Decker , Raymond Yan

To gain insight into complex systems it is a key challenge to infer nonlinear causal directional relations from observational time-series data. Specifically, estimating causal relationships between interacting components in large systems…

机器学习 · 计算机科学 2021-11-04 Axel Wismüller , Adora M. DSouza , Anas Z. Abidin

We consider the problem of inferring the conditional independence graph (CIG) of a high-dimensional stationary multivariate Gaussian time series. In a time series graph, each component of the vector series is represented by distinct node,…

机器学习 · 统计学 2022-05-03 Jitendra K Tugnait