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Data-driven cell tracking and segmentation methods in biomedical imaging require diverse and information-rich training data. In cases where the number of training samples is limited, synthetic computer-generated data sets can be used to…

计算机视觉与模式识别 · 计算机科学 2023-10-16 David Wiesner , Julian Suk , Sven Dummer , Tereza Nečasová , Vladimír Ulman , David Svoboda , Jelmer M. Wolterink

Generative modeling has become a central paradigm in protein research, extending machine learning beyond structure prediction toward sequence design, backbone generation, inverse folding, and biomolecular interaction modeling. However, the…

机器学习 · 计算机科学 2026-03-30 Senura Hansaja Wanasekara , Minh-Duong Nguyen , Xiaochen Liu , Nguyen H. Tran , Ken-Tye Yong

Generative models learn the distribution of data from a sample dataset and can then generate new data instances. Recent advances in deep learning has brought forth improvements in generative model architectures, and some state-of-the-art…

密码学与安全 · 计算机科学 2021-07-30 Luke A. Bauer , Vincent Bindschaedler

Generative neural networks can produce data samples according to the statistical properties of their training distribution. This feature can be used to test modern computational neuroscience hypotheses suggesting that spontaneous brain…

神经与进化计算 · 计算机科学 2025-07-29 Lorenzo Tausani , Alberto Testolin , Marco Zorzi

Social interactions incorporate nonverbal signals to convey emotions alongside speech, including facial expressions and body gestures. Generative models have demonstrated promising results in creating full-body nonverbal animations…

人机交互 · 计算机科学 2026-04-01 Kiran Chhatre , Renan Guarese , Andrii Matviienko , Christopher Peters

Deep generative models, such as Generative Adversarial Networks (GANs) or Variational Autoencoders (VAs) have been demonstrated to produce images of high visual quality. However, the existing hardware severely limits the size of the images…

Data availability plays a critical role for the performance of deep learning systems. This challenge is especially acute within the medical image domain, particularly when pathologies are involved, due to two factors: 1) limited number of…

计算机视觉与模式识别 · 计算机科学 2018-06-12 Dakai Jin , Ziyue Xu , Youbao Tang , Adam P. Harrison , Daniel J. Mollura

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

生物大分子 · 定量生物学 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

Generating novel active molecules for a given protein is an extremely challenging task for generative models that requires an understanding of the complex physical interactions between the molecule and its environment. In this paper, we…

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

机器学习 · 统计学 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

Diffusion models have emerged as a powerful new family of deep generative models with record-breaking performance in many applications, including image synthesis, video generation, and molecule design. In this survey, we provide an overview…

机器学习 · 计算机科学 2025-09-30 Ling Yang , Zhilong Zhang , Yang Song , Shenda Hong , Runsheng Xu , Yue Zhao , Wentao Zhang , Bin Cui , Ming-Hsuan Yang

Spatio-temporal (3D+t) generative modelling of cardiac shape and motion is crucial for understanding heart structure and function at population scale. Existing generative models for cardiac shape synthesis either adopt volumetric shape…

图像与视频处理 · 电气工程与系统科学 2026-05-05 Qiang Ma , Qingjie Meng , Mengyun Qiao , Paul M. Matthews , Declan P. O'Regan , Wenjia Bai

Generative latent diffusion models have been established as state-of-the-art in data generation. One promising application is generation of realistic synthetic medical imaging data for open data sharing without compromising patient privacy.…

计算机视觉与模式识别 · 计算机科学 2023-07-07 Salman Ul Hassan Dar , Arman Ghanaat , Jannik Kahmann , Isabelle Ayx , Theano Papavassiliu , Stefan O. Schoenberg , Sandy Engelhardt

3D city generation is a desirable yet challenging task, since humans are more sensitive to structural distortions in urban environments. Additionally, generating 3D cities is more complex than 3D natural scenes since buildings, as objects…

计算机视觉与模式识别 · 计算机科学 2024-06-07 Haozhe Xie , Zhaoxi Chen , Fangzhou Hong , Ziwei Liu

Random graph models are frequently used as a controllable and versatile data source for experimental campaigns in various research fields. Generating such data-sets at scale is a non-trivial task as it requires design decisions typically…

数据结构与算法 · 计算机科学 2020-03-03 Manuel Penschuck , Ulrik Brandes , Michael Hamann , Sebastian Lamm , Ulrich Meyer , Ilya Safro , Peter Sanders , Christian Schulz

The field of image generation through generative modelling is abundantly discussed nowadays. It can be used for various applications, such as up-scaling existing images, creating non-existing objects, such as interior design scenes,…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Giorgia Adorni , Felix Boelter , Stefano Carlo Lambertenghi

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Generating virtual populations of anatomy that capture sufficient variability while remaining plausible is essential for conducting in-silico trials of medical devices. However, not all anatomical shapes of interest are always available for…

图像与视频处理 · 电气工程与系统科学 2024-03-05 Haoran Dou , Seppo Virtanen , Nishant Ravikumar , Alejandro F. Frangi

Cryo-EM reconstruction algorithms seek to determine a molecule's 3D density map from a series of noisy, unlabeled 2D projection images captured with an electron microscope. Although reconstruction algorithms typically model the 3D volume as…

生物大分子 · 定量生物学 2021-07-06 Ellen D. Zhong , Adam Lerer , Joseph H. Davis , Bonnie Berger

3D-aware generative adversarial networks (GANs) synthesize high-fidelity and multi-view-consistent facial images using only collections of single-view 2D imagery. Towards fine-grained control over facial attributes, recent efforts…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Jingxiang Sun , Xuan Wang , Lizhen Wang , Xiaoyu Li , Yong Zhang , Hongwen Zhang , Yebin Liu