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Robotic laser systems offer the potential for sub-millimeter, non-contact, high-precision tissue resection, yet existing platforms lack volumetric planning and intraoperative feedback. We present RATS (Robot-Assisted Tissue Surgery), an…

FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely,…

Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor…

Radiation therapy (RT) aims to deliver tumoricidal doses with minimal radiation-induced normal-tissue toxicity. Compared to conventional RT (of conventional dose rate), FLASH-RT (of ultra-high dose rate) can provide additional normal tissue…

最优化与控制 · 数学 2023-11-27 Fengmiao Bian , Jiulong Liu , Xiaoqun Zhang , Hao Gao , Jian-Feng Cai

A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the…

Radiotherapy is one of the primary treatment methods for tumors, but the organ movement caused by respiration limits its accuracy. Recently, 3D imaging from a single X-ray projection has received extensive attention as a promising approach…

图像与视频处理 · 电气工程与系统科学 2024-04-01 Miao Zhu , Qiming Fu , Bo Liu , Mengxi Zhang , Bojian Li , Xiaoyan Luo , Fugen Zhou

While spatial dose conformity delivered to a target volume has been pushed to its practical limits with advanced treatment planning and delivery, investigations in novel temporal dose delivery are unfolding new mechanisms. Recent advances…

Low-surface-brightness (LSB) structures provide critical insights into the hierarchical formation of galaxies and galaxy clusters. The KASI Deep Rolling Imaging Fast Telescope (K-DRIFT) is designed to detect such diffuse features through…

Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel treatment that delivers radiation in pulses of protracted intervals. Accurate prediction of gross tumor volume (GTV) changes through regression models…

机器学习 · 计算机科学 2025-09-18 Yajun Yu , Steve Jiang , Robert Timmerman , Hao Peng

We developed a mathematical model to simulate the growth of tumor volume and its response to a single fraction of high dose irradiation. We made several key assumptions of the model. Tumor volume is composed of proliferating (or dividing)…

医学物理 · 物理学 2015-11-13 Yoichi Watanabe , Erik L. Dahlman , Kevin Z. Leder , Susanta K. Hui

Radiotherapy continues to become more precise and data dense, with current treatment regimens generating high frequency imaging and dosimetry streams ideally suited for AI driven temporal modeling to characterize how normal tissues evolve…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Anvi Sud , Jialu Huang , Gregory R. Hart , Keshav Saxena , John Kim , Lauren Tressel , Jun Deng

Purpose. - Radiotherapy is an important treatment for prostate cancer.During treatment sessions, bladder and rectal repletion is difficult to quantify and cannot be measured with a single and initial CT scan acquisition. Some methods, such…

The purpose of our study is to develop a new, 3-dimensional dosimetry system to verify the accuracy of dose deliveries in Leksell Gamma Knife-Perfexion TM (LGKP) (Elekta, Norcross, GA, USA). The instrument consists of a moving head phantom,…

医学物理 · 物理学 2015-03-12 KyoungJun Yoon , JungWon Kwak , DoHeui Lee , ByungChul Cho , SangWook Lee , SeungDo Ahn

Purpose: To provide a fast computational method, based on the proximal graph solver (POGS) - a convex optimization solver using the alternating direction method of multipliers (ADMM), for calculating an optimal treatment plan in rotating…

医学物理 · 物理学 2018-02-07 Myung Cho , Xiaodong Wu , Hossein Dakhah , Jirong Yi , Ryan T. Flynn , Yusung Kim , Weiyu Xu

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

医学物理 · 物理学 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

A new strategy for radiation therapy dosimetry planning (RTDP) used to reduce dose estimation errors due to respiratory motion in breast treatment was illustrated and evaluated in this study. On CT data set acquired for breast treatment,…

医学物理 · 物理学 2021-10-20 Mazen Moussallem , Pauline Harb , Hanane Rima , Zeina Al Kattar , Saad Ayoubi

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

医学物理 · 物理学 2015-06-15 Hamed Yarmand , David Craft

Background: In vivo dosimetry is essential for treatment verification in modern radiotherapy, but existing techniques are limited by spatiotemporal resolution and performance on non-uniform anatomy. Scintillation imaging dosimetry shows…

Radiotherapy dosimetry plays a crucial role in optimizing treatment plans for cancer patients. In this study, we investigate the performance of a dozen standard state-of-the-art open-source optimizers for radiotherapy dosimetry. Our…

系统与控制 · 电气工程与系统科学 2023-05-30 Paul Dubois
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