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Foundation models (FMs) are increasingly spearheading recent advances on a variety of tasks that fall under the purview of computer audition -- the use of machines to understand sounds. They feature several advantages over traditional…

The field of single-cell biology is growing rapidly and is generating large amounts of data from a variety of species, disease conditions, tissues, and organs. Coordinated efforts such as CZI CELLxGENE, HuBMAP, Broad Institute Single Cell…

Big science initiatives are trying to reconstruct and model the brain by attempting to simulate brain tissue at larger scales and with increasingly more biological detail than previously thought possible. The exponential growth of parallel…

性能 · 计算机科学 2020-06-25 Francesco Cremonesi , Georg Hager , Gerhard Wellein , Felix Schürmann

Deep learning is an advanced technology that relies on large-scale data and complex models for feature extraction and pattern recognition. It has been widely applied across various fields, including computer vision, natural language…

基因组学 · 定量生物学 2024-12-24 Yindan Luo , Jiaxin Cai

This informal contribution presents an ongoing line of research that is pursuing a new approach to the construction of sound proofs for the formal verification and control of complex stochastic models of dynamical systems, of reactive…

系统与控制 · 电气工程与系统科学 2025-12-23 Alessandro Abate

Cell competition is a quality control mechanism in tissues that results in the elimination of less fit cells. Over the past decade, the phenomenon of cell competition has been identified in many physiological and pathological contexts,…

组织与器官 · 定量生物学 2019-03-26 Daniel Gradeci , Anna Bove , Guillaume Charras , Alan R. Lowe , Shiladitya Banerjee

Simulations play important and diverse roles in statistical workflows, for example, in model specification, checking, validation, and even directly in model inference. Over the past decades, the application areas and overall potential of…

统计计算 · 统计学 2025-08-27 Paul-Christian Bürkner , Marvin Schmitt , Stefan T. Radev

Audio classification is paramount in a variety of applications including surveillance, healthcare monitoring, and environmental analysis. Traditional methods frequently depend on intricate signal processing algorithms and manually crafted…

声音 · 计算机科学 2025-02-24 Amlan Basu , Pranav Chaudhari , Gaetano Di Caterina

This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features that make R…

基因组学 · 定量生物学 2014-01-14 Laurent Gatto , Andy Christoforou

Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

生物物理 · 物理学 2023-10-10 David B. Brückner , Chase P. Broedersz

This paper reviews the state-of-the-art of semantic change computation, one emerging research field in computational linguistics, proposing a framework that summarizes the literature by identifying and expounding five essential components…

计算与语言 · 计算机科学 2018-06-20 Xuri Tang

As new technologies move to the fore, our understanding of the world may seem to have shrunk in comparison, for despite new developments in research, much of it is reduced or rather, abstracted for marketability. Thus, the purpose of this…

计算机与社会 · 计算机科学 2017-01-24 Katherine Hughes

The complexity of exploratory data analysis poses significant challenges for collaboration and effective communication of analytic workflows. Automated methods can alleviate these challenges by summarizing workflows into more interpretable…

人机交互 · 计算机科学 2024-10-16 Shaghayegh Esmaeili , Irelis D. Suarez , Ezekiel Ajayi , Eric D. Ragan

Protein function does not solely depend on structure but often relies on dynamical transitions between distinct conformations. Despite this fact, our ability to characterize or predict protein dynamics is substantially less developed…

统计力学 · 物理学 2026-05-08 Michael A. Sauer , Souvik Mondal , Brandon Neff , Sthitadhi Maiti , Matthias Heyden

We review methods of data analysis for biophysical data with a special emphasis on single molecule applications. Our review is intended for anyone, from student to established researcher. For someone just getting started, we focus on…

生物物理 · 物理学 2016-11-24 Meysam Tavakoli , J. Nicholas Taylor , Chun-Biu Li , Tamiki Komatsuzaki , Steve Pressé

Bioacoustics, the study of sounds produced by living organisms, plays a vital role in conservation, biodiversity monitoring, and behavioral studies. Many tasks in this field, such as species, individual, and behavior classification and…

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

应用统计 · 统计学 2019-12-19 Jiawei Long , Yu Xia

In the world of science new technology have opened up the possibility to rely on advanced computational methods and models to conduct and produce scientific research. An important aspect of scientific and business workflows is provenance -…

软件工程 · 计算机科学 2025-04-01 Ludwig Stage , Julia Dahlberg , Dimka Karastoyanova

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Understanding protein solubility is essential for their functional applications. Computational methods for predicting protein solubility are crucial for reducing experimental costs and enhancing the efficiency and success rates of protein…

定量方法 · 定量生物学 2024-07-01 Yang Tan , Jia Zheng , Liang Hong , Bingxin Zhou