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Ion computed tomography (iCT) is an imaging modality for the direct determination of the relative stopping power (RSP) distribution within a patient's body. Usually, this is done by estimating the path and energy loss of ions traversing the…

For dose calculations in ion beam therapy, it is vital to accurately determine the relative stopping power (RSP) distribution within the treated volume. Currently, RSP values are extrapolated from Hounsfield units (HU), measured with x-ray…

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

医学物理 · 物理学 2022-01-26 S. Sajedi , L. Blackberg , S. Majewski , H. Sabet

Proton computed tomography (CT) is similar to x-ray CT but relies on protons rather than photons to form an image. In its most common operation mode, the measured quantity is the amount of energy that a proton has lost while traversing the…

医学物理 · 物理学 2022-08-17 Nils Krah , Denis Dauvergne , Jean Michel Létang , Simon Rit , Étienne Testa

Recently, we reported an ion trap experiment with an integrated time-of-flight mass spectrometer (TOFMS) [Phys. Rev. Appl. 2, 034013 (2014)] focussing on the improvement of mass resolution and detection limit due to sample preparation at…

原子物理 · 物理学 2016-01-20 Christian Schneider , Steven J. Schowalter , Peter Yu , Eric R. Hudson

The Time-of-Flight (ToF) technique coupled with semiconductor-like detectors, as silicon carbide and diamond, is one of the most promising diagnostic methods for high-energy, high repetition rate, laser-accelerated ions allowing a full…

Cone beam computed tomography (CBCT) for breast imaging has potential to replace conventional mammograms. However, concerns over dose and image quality prevent CBBCT systems from the clinical trial phase to next stage. The time of flight…

医学物理 · 物理学 2021-02-01 Ignacio O. Romero , Changqing Li

Two major challenges in time-of-flight positron emission tomography (TOF-PET) are low spatial resolution and high radioactive dose to the patient, both of which result from limitations in detection technology rather than fundamental…

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

仪器与探测器 · 物理学 2009-08-03 P. -E. Vert , J. Lecoq , G. Montarou , N. Pauna , B. Joly , M. Boutemeur , H. Mathez , R. Gaglione , P. Le Dû

In applied forms of time-of-flight mass spectrometry utilizing ion storage devices prior to an analysis device, a non instantaneous electric ejection pulse applied in the region of ion storage is used to accelerate ions into the…

仪器与探测器 · 物理学 2023-07-19 M. Rosenbusch , P. Schury , M. Wada , S. Iimura , Y. Ito , H. Wollnik

Nowadays, in Positron Emission Tomography (PET) systems, a Time of Flight information is used to improve the image reconstruction process. In Time of Flight PET (TOF-PET), fast detectors are able to measure the difference in the arrival…

Prompt Gamma Timing (PGT) is a promising technique for in vivo range verification in particle therapy, exploiting the time-of-flight between primary particles and prompt gamma rays emitted by nuclear interactions. PGT distribution is highly…

To achieve high precision and accuracy for mass measurements of exotic nuclei by Time-of-flight (TOF) methods: high-resolution beam-line magnetic-rigidity time-of-flight (B$\rho$-TOF) and in-ring isochronous mass spectrometry (IMS), a…

仪器与探测器 · 物理学 2024-07-16 Zhuang Ge

Radiation therapy with carbon ions is a novel technique of cancer radiotherapy, applicable in particular to treating radioresistant tumours at difficult localisations. Therapy planning, where the medical physicist, following the medical…

医学物理 · 物理学 2014-10-07 Leszek Grzanka

Time-Of-Flight (TOF) is a noble technique that is used in Positron Emission Tomography (PET) imaging worldwide. The scintillator based imaging system that is being used around the world for TOF-PET is very expensive. Multi-gap Resistive…

An analytical method is presented with allows to estimate the energy resolution of time-of-flight neutron spectrometers, as well as its partial contributions, over a dynamical range that extends from the elastic line to the accessible…

仪器与探测器 · 物理学 2009-12-05 Ana M Gaspar

Time-Of-Flight (TOF) methods are very effective to detect particles accelerated in laser-plasma interactions, but they shows significant limitations when used in experiments with high energy and intensity lasers, where both high-energy ions…

This paper introduces a new scheme of ion beam figuring (IBF), or rather variable-spot IBF, which is conducted at a constant scanning velocity with variable-spot ion beam collimated by a variable diaphragm. It aims at improving the…

仪器与探测器 · 物理学 2016-02-17 Lixiang Wu , Keqiang Qiu , Shaojun Fu

In recent years, computational Time-of-Flight (ToF) imaging has emerged as an exciting and a novel imaging modality that offers new and powerful interpretations of natural scenes, with applications extending to 3D, light-in-flight, and…

图像与视频处理 · 电气工程与系统科学 2024-11-05 Ruiming Guo , Ayush Bhandari

Plastic scintillation detectors for Time-of-Flight (TOF) measurements are almost essential for event-by-event identification of relativistic rare isotopes. In this work, a pair of plastic scintillation detectors of 50 $\times$ 50 $\times$…

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