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Evaluating the causal effect of an intervention on multivariate outcomes is challenging when the outcomes are interdependent and derived rather than directly observed. Effective connectivity, which summarizes the directional neural…

统计方法学 · 统计学 2026-04-02 Haiyue Song , Ani Eloyan , Youjin Lee

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

统计计算 · 统计学 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

神经元与认知 · 定量生物学 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in…

神经元与认知 · 定量生物学 2019-07-03 Ahmed El Gazzar , Leonardo Cerliani , Guido van Wingen , Rajat Mani Thomas

This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…

The classification of random objects within metric spaces without a vector structure has attracted increasing attention. However, the complexity inherent in such non-Euclidean data often restricts existing models to handle only a limited…

统计方法学 · 统计学 2024-03-20 Shuaida He , Jiaqi Li , Xin Chen

The problem of jointly analysing functional connectomics and behavioral data is extremely challenging owing to the complex interactions between the two domains. In addition, clinical rs-fMRI studies often have to contend with limited…

机器学习 · 计算机科学 2023-01-18 Niharika Shimona D'Souza

We propose a novel quantile function-based approach for neuroimaging classification using Wasserstein-Fr\'echet regression, specifically applied to the detection of mild traumatic brain injury (mTBI) based on the MEG and MRI data.…

应用统计 · 统计学 2025-09-01 Jie Li , Gary Green , Jian Zhang

Resting-state functional magnetic resonance imaging (rs-fMRI)-derived functional connectivity patterns have been extensively utilized to delineate global functional organization of the human brain in health, development, and…

定量方法 · 定量生物学 2020-10-02 Li Xiao , Biao Cai , Gang Qu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Mutual information maximization has emerged as a powerful learning objective for unsupervised representation learning obtaining state-of-the-art performance in applications such as object recognition, speech recognition, and reinforcement…

机器学习 · 计算机科学 2019-03-29 Sherjil Ozair , Corey Lynch , Yoshua Bengio , Aaron van den Oord , Sergey Levine , Pierre Sermanet

Emotions are an essential part of human behavior that can impact thinking, decision-making, and communication skills. Thus, the ability to accurately monitor and identify emotions can be useful in many human-centered applications such as…

机器学习 · 计算机科学 2023-08-22 Nibraas Khan , Mahrukh Tauseef , Ritam Ghosh , Nilanjan Sarkar

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Junhao Jia , Yifei Sun , Yunyou Liu , Cheng Yang , Changmiao Wang , Feiwei Qin , Yong Peng , Wenwen Min

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

应用统计 · 统计学 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

神经元与认知 · 定量生物学 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Autism spectrum disorder is a neuro-developmental disorder characterized by abnormalities of neural synchronization. In this study, functional near infrared spectroscopy (fNIRS) is used to study the difference in functional connectivity in…

神经元与认知 · 定量生物学 2013-09-24 Huilin Zhu , Yuebo Fan , Huan Guo , Dan Huang , Sailing He

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that encompasses a wide variety of symptoms and degrees of impairment, which makes the diagnosis and treatment challenging. Functional magnetic resonance imaging (fMRI) has…

计算机视觉与模式识别 · 计算机科学 2024-09-20 Yinchi Zhou , Peiyu Duan , Yuexi Du , Nicha C. Dvornek

Functional magnetic resonance imaging or functional MRI (fMRI) is a very popular tool used for differing brain regions by measuring brain activity. It is affected by physiological noise, such as head and brain movement in the scanner from…

统计方法学 · 统计学 2023-10-30 Fangyijie Wang , Michael Salter-Townshend

Functional brain network properties are heavily influenced by how the the network nodes are defined. A common approach uses Regions of Interest (ROIs), i.e., predetermined collections of functional magnetic resonance imaging (fMRI)…

神经元与认知 · 定量生物学 2025-03-07 Tarmo Nurmi , Pietro De Luca , Maria Hakonen , Mikko Kivelä , Onerva Korhonen

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

神经元与认知 · 定量生物学 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu