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The goal of privacy metrics is to measure the degree of privacy enjoyed by users in a system and the amount of protection offered by privacy-enhancing technologies. In this way, privacy metrics contribute to improving user privacy in the…

密码学与安全 · 计算机科学 2018-06-21 Isabel Wagner , David Eckhoff

In the past decade, Genome-Wide Association Studies (GWAS) have delivered an increasingly broad view of the genetic basis of human phenotypic variation. One of the major developments from GWAS is polygenic scores, a genetic predictor of an…

基因组学 · 定量生物学 2019-09-04 Graham Coop

Genetic data collection has become ubiquitous, producing genetic information about health, ancestry, and social traits. However, unregulated use, especially amid evolving scientific understanding, poses serious privacy and discrimination…

计算机与社会 · 计算机科学 2025-06-03 Vivek Ramanan , Ria Vinod , Cole Williams , Sohini Ramachandran , Suresh Venkatasubramanian

Polygenic risk scores (PRS) developed from genome-wide association studies (GWAS) can be used for risk stratification by quantifying the genetic contribution to disease, and many clinical applications have been proposed. Bayesian methods…

统计方法学 · 统计学 2026-03-11 Yuzheng Dun , Nilanjan Chatterjee , Jin Jin , Akihiko Nishimura

Quantitatively predicting phenotype variables by the expression changes in a set of candidate genes is of great interest in molecular biology but it is also a challenging task for several reasons. First, the collected biological…

应用统计 · 统计学 2017-07-21 Emilie Devijver , Mélina Gallopin , Emeline Perthame

This work proposes a novel privacy-preserving neural network feature representation to suppress the sensitive information of a learned space while maintaining the utility of the data. The new international regulation for personal data…

计算机视觉与模式识别 · 计算机科学 2020-08-10 Aythami Morales , Julian Fierrez , Ruben Vera-Rodriguez , Ruben Tolosana

Using real-world study data usually requires contractual agreements where research results may only be published in anonymized form. Requiring formal privacy guarantees, such as differential privacy, could be helpful for data-driven…

密码学与安全 · 计算机科学 2024-07-08 Jonas Allmann , Saskia Nuñez von Voigt , Florian Tschorsch

Differential privacy allows quantifying privacy loss resulting from accessing sensitive personal data. Repeated accesses to underlying data incur increasing loss. Releasing data as privacy-preserving synthetic data would avoid this…

机器学习 · 统计学 2021-06-10 Joonas Jälkö , Eemil Lagerspetz , Jari Haukka , Sasu Tarkoma , Antti Honkela , Samuel Kaski

We study statistical risk minimization problems under a privacy model in which the data is kept confidential even from the learner. In this local privacy framework, we establish sharp upper and lower bounds on the convergence rates of…

机器学习 · 统计学 2013-10-11 John C. Duchi , Michael I. Jordan , Martin J. Wainwright

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

基因组学 · 定量生物学 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

Polygnicity refers to the phenomenon that multiple genetic variants have a non-zero effect on a complex trait. It is defined as the proportion of genetic variants that have a nonzero effect on the trait. Evaluation of polygenicity can…

基因组学 · 定量生物学 2022-07-26 Arunabha Majumdar , Bogdan Pasaniuc

A tremendous amount of individual-level data is generated each day, of use to marketing, decision makers, and machine learning applications. This data often contain private and sensitive information about individuals, which can be disclosed…

密码学与安全 · 计算机科学 2019-01-23 Marmar Orooji , Gerald M. Knapp

We are entering the era of ubiquitous genetic information for research, clinical care, and personal curiosity. Sharing these datasets is vital for rapid progress in understanding the genetic basis of human diseases. However, one growing…

基因组学 · 定量生物学 2013-10-14 Yaniv Erlich , Arvind Narayanan

Software applications have become an omnipresent part of modern society. The consequent privacy policies of these applications play a significant role in informing customers how their personal information is collected, stored, and used.…

密码学与安全 · 计算机科学 2023-06-21 Shidong Pan , Thong Hoang , Dawen Zhang , Zhenchang Xing , Xiwei Xu , Qinghua Lu , Mark Staples

Statistical heterogeneity is a measure of how skewed the samples of a dataset are. It is a common problem in the study of differential privacy that the usage of a statistically heterogeneous dataset results in a significant loss of…

机器学习 · 计算机科学 2024-12-02 Mary Scott , Graham Cormode , Carsten Maple

Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a…

密码学与安全 · 计算机科学 2018-08-20 Alexandros Mittos , Bradley Malin , Emiliano De Cristofaro

An increasing number of individuals are turning to Direct-To-Consumer (DTC) genetic testing to learn about their predisposition to diseases, traits, and/or ancestry. DTC companies like 23andme and Ancestry.com have started to offer popular…

密码学与安全 · 计算机科学 2016-11-11 Emiliano De Cristofaro , Kaitai Liang , Yuruo Zhang

Recent advances in score-based generative models have led to a huge spike in the development of downstream applications using generative models ranging from data augmentation over image and video generation to anomaly detection. Despite…

计算机视觉与模式识别 · 计算机科学 2023-06-05 Mischa Dombrowski , Bernhard Kainz

Huge volume of data from domain specific applications such as medical, financial, telephone, shopping records and individuals are regularly generated. Sharing of these data is proved to be beneficial for data mining application. Since data…

统计方法学 · 统计学 2014-03-21 Hitesh Chhinkaniwala , Sanjay Garg

Recently introduced privacy legislation has aimed to restrict and control the amount of personal data published by companies and shared to third parties. Much of this real data is not only sensitive requiring anonymization, but also…

数据库 · 计算机科学 2020-07-20 Mostafa Milani , Yu Huang , Fei Chiang