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Survival analysis is an important research topic with applications in healthcare, business, and manufacturing. One essential tool in this area is the Cox proportional hazards (CPH) model, which is widely used for its interpretability,…

机器学习 · 计算机科学 2024-10-28 Jiachang Liu , Rui Zhang , Cynthia Rudin

Semi-parametric survival analysis methods like the Cox Proportional Hazards (CPH) regression (Cox, 1972) are a popular approach for survival analysis. These methods involve fitting of the log-proportional hazard as a function of the…

机器学习 · 计算机科学 2019-05-16 Chirag Nagpal , Rohan Sangave , Amit Chahar , Parth Shah , Artur Dubrawski , Bhiksha Raj

Prognostic models in survival analysis are aimed at understanding the relationship between patients' covariates and the distribution of survival time. Traditionally, semi-parametric models, such as the Cox model, have been assumed. These…

机器学习 · 统计学 2020-11-06 Denise Rava , Jelena Bradic

Survival analysis is a widely known method for predicting the likelihood of an event over time. The challenge of dealing with censored samples still remains. Traditional methods, such as the Cox Proportional Hazards (CPH) model, hinge on…

机器学习 · 计算机科学 2025-01-10 Chanon Puttanawarut , Panu Looareesuwan , Romen Samuel Wabina , Prut Saowaprut

The Cox Proportional Hazards (CPH) model has long been the preferred survival model for its explainability. However, to increase its predictive power beyond its linear log-risk, it was extended to utilize deep neural networks, sacrificing…

机器学习 · 计算机科学 2025-12-02 Abdallah Alabdallah , Omar Hamed , Mattias Ohlsson , Thorsteinn Rögnvaldsson , Sepideh Pashami

Medical practitioners use survival models to explore and understand the relationships between patients' covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the…

Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally…

机器学习 · 计算机科学 2022-07-12 Dekai Zhang , Francesca Toni , Matthew Williams

Survival prediction is an important branch of cancer prognosis analysis. The model that predicts survival risk through TCGA genomics data can discover genes related to cancer and provide diagnosis and treatment recommendations based on…

机器学习 · 计算机科学 2024-05-14 Wankang Zhai

Variable selection problem for the nonlinear Cox regression model is considered. In survival analysis, one main objective is to identify the covariates that are associated with the risk of experiencing the event of interest. The Cox…

机器学习 · 统计学 2022-11-18 Kexuan Li

The Cox proportional hazards (CPH) model has been widely applied in survival analysis to estimate relative risks across different subjects given multiple covariates. Traditional CPH models rely on a linear combination of covariates weighted…

机器学习 · 计算机科学 2025-04-28 Jiaxiang Cheng , Guoqiang Hu

New methods for time-to-event prediction are proposed by extending the Cox proportional hazards model with neural networks. Building on methodology from nested case-control studies, we propose a loss function that scales well to large data…

机器学习 · 统计学 2019-09-16 Håvard Kvamme , Ørnulf Borgan , Ida Scheel

In this study, we address the challenge of survival analysis within heterogeneous patient populations, where traditional reliance on a single regression model such as the Cox proportional hazards (Cox PH) model often falls short.…

统计方法学 · 统计学 2025-04-15 Ahmad Talafha

We revisit Cox's proportional hazard models and LASSO in the aim of improving feature selection in survival analysis. Unlike traditional methods relying on cross-validation or BIC, the penalty parameter $\lambda$ is directly tuned for…

机器学习 · 统计学 2025-10-23 Maxime van Cutsem , Sylvain Sardy

Survival models are a popular tool for the analysis of time to event data with applications in medicine, engineering, economics, and many more. Advances like the Cox proportional hazard model have enabled researchers to better describe…

机器学习 · 统计学 2021-02-16 Stefan Groha , Sebastian M Schmon , Alexander Gusev

Survival analysis is a widely used statistical framework for modeling time-to-event data under censoring. Classical methods, such as the Cox proportional hazards (Cox PH) model, offer a semiparametric approach to estimating the effects of…

机器学习 · 统计学 2026-04-23 Yang Xu , Wenbin Lu , Rui Song

While analysing time-to-event data, it is possible that a certain fraction of subjects will never experience the event of interest and they are said to be cured. When this feature of survival models is taken into account, the models are…

统计方法学 · 统计学 2020-01-27 Khandoker Akib Mohammad , Yuichi Hirose , Budhi Surya , Yuan Yao

Survival analysis is widely deployed in a diverse set of fields, including healthcare, business, ecology, etc. The Cox Proportional Hazard (CoxPH) model is a semi-parametric model often encountered in the literature. Despite its popularity,…

机器学习 · 计算机科学 2025-05-29 Chengzhi Shi , Stratis Ioannidis

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

机器学习 · 计算机科学 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

The Cox model, which remains as the first choice in analyzing time-to-event data even for large datasets, relies on the proportional hazards (PH) assumption. When survival data arrive sequentially in chunks, a fast and minimally storage…

统计方法学 · 统计学 2020-11-24 Yishu Xue , HaiYing Wang , Jun Yan , Elizabeth D. Schifano

Survival analysis often relies on Cox models, assuming both linearity and proportional hazards (PH). This study evaluates machine and deep learning methods that relax these constraints, comparing their performance with penalized Cox models…

机器学习 · 计算机科学 2025-10-21 Ivan Rossi , Flavio Sartori , Cesare Rollo , Giovanni Birolo , Piero Fariselli , Tiziana Sanavia
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