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In this paper we present a new 3D segmentation approach for the vertebrae of the lower thoracic and the lumbar spine in spiral computed tomography datasets. We implemented a multi-step procedure. Its main components are deformable models,…

计算机视觉与模式识别 · 计算机科学 2020-12-11 Andre Mastmeyer , Klaus Engelke , Sebastian Meller , Willi Kalender

Computer hardware costs are the limiting factor in producing highly accurate radiation dose calculations on convenient time scales. Because of this, large-scale, full Monte Carlo simulations and other resource intensive algorithms are often…

医学物理 · 物理学 2010-09-28 Roy W. Keyes , Christian Romano , Dorian Arnold , Shuang Luan

Irregular bone remodeling is associated with a number of bone diseases such as osteoporosis and multiple myeloma. Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology.…

定量方法 · 定量生物学 2023-02-14 Jason M. Graham , Bruce P. Ayati , Prem S. Ramakrishnan , James A. Martin

This work summarises the results of a comparison organized by EURADOS focused on the usage of the ICRP Reference Computational Phantoms. This activity aimed to provide training for the implementation of voxel phantoms in Monte Carlo…

An essential component in proton radiotherapy is the algorithm to calculate the radiation dose to be delivered to the patient. The most common dose algorithms are fast but they are approximate analytical approaches. However their level of…

医学物理 · 物理学 2015-05-20 Pablo P Yepes , Dragan Mirkovic , Phillip J Taddei

Although one-loop calculations provide a realistic description of bulk and single-particle nuclear properties, it is necessary to examine loop corrections to develop a systematic finite-density power-counting scheme for the nuclear…

核理论 · 物理学 2008-11-26 Ying Hu , Jeff McIntire , Brian D. Serot

The paper presents an investigation of estimating treatment effect using different matching methods. The study proposed a new method which is computationally efficient and convenient in implication-'largest caliper matching' and compared…

应用统计 · 统计学 2018-06-07 Sharif Mahmood

This study conceptualizes electronic dose to water, which is the radiation energy imparted to a unit mass of water by electronic interactions. The new dosimetry framework excludes nuclear interactions and consequently associated corrections…

医学物理 · 物理学 2026-03-11 Nobuyuki Kanematsu

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

Pencil x-ray beam imaging provides superior spatial resolution than other imaging geometries like sheet beam and cone beam geometries due to the illumination of a line instead of an area or volume. However, the pencil beam geometry suffers…

医学物理 · 物理学 2021-02-01 Ignacio O. Romero , Changqing Li

In the recently published article by T.M. Gray et al. "Microdosimetric and radiobiological effects of gold nanoparticles at therapeutic radiation energies" (IJRB 2023, 99(2), 308-317) results of Monte Carlo simulations and radiobiological…

医学物理 · 物理学 2023-08-15 Hans Rabus , Miriam Schwarze , Leo Thomas

The use of sparse precision (inverse covariance) matrices has become popular because they allow for efficient algorithms for joint inference in high-dimensional models. Many applications require the computation of certain elements of the…

统计计算 · 统计学 2017-12-06 Per Sidén , Finn Lindgren , David Bolin , Mattias Villani

Deep neural networks have become the gold-standard approach for the automated segmentation of 3D medical images. Their full acceptance by clinicians remains however hampered by the lack of intelligible uncertainty assessment of the provided…

图像与视频处理 · 电气工程与系统科学 2022-09-23 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

The Centers for Medicare & Medicaid Services (CMS) has introduced CMS1074v2, a quality measure for computed tomography (CT) that assesses radiation dose and image quality across 18 CT exam categories. This measure mandates the calculation…

医学物理 · 物理学 2025-03-11 Gary Y Ge , Charles M Weaver , Jie Zhang

Deep-learning-based approaches for retinal lesion segmentation often require an abundant amount of precise pixel-wise annotated data. However, coarse annotations such as circles or ellipses for outlining the lesion area can be six times…

计算机视觉与模式识别 · 计算机科学 2022-08-31 Qinji Yu , Kang Dang , Ziyu Zhou , Yongwei Chen , Xiaowei Ding

This study evaluates the uncertainty in nanodosimetric calculations caused by variations in interaction cross sections within Monte Carlo Track Structure (MCTS) simulation codes. Nanodosimetry relies on accurately simulating particle…

The matrix element technique provides a superior statistical sensitivity for precision measurements of important parameters at hadron colliders, such as the mass of the top quark or the cross section for the production of Higgs bosons. The…

高能物理 - 实验 · 物理学 2014-11-20 Oleg Brandt , Gaston Gutierrez , Michael H. L. S. Wang , Zhenyu Ye

Radiation dosimetry systems are complex systems, comprised of a milieu of components, designed for determining absorbed dose after exposure to ionizing radiation. Although many materials serve as absorbing media for measurement,…

医学物理 · 物理学 2013-09-12 Luisiana X. Cundin

The electronic density of states (DOS) provides information regarding the distribution of electronic energy levels in a material, and can be used to approximate its optical and electronic properties and therefore guide computational…

Statistical methods such as sequential Monte Carlo Methods were proposed for detection, segmentation and tracking of objects in digital images. A similar approach, called Shape Particle Filters was introduced for the segmentation of…

计算机视觉与模式识别 · 计算机科学 2015-06-23 Z. Bardosi , D. Granata , G. Lugos , A. P. Tafti , S. Saxena