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Unlike common cancers, such as those of the prostate and breast, tumor grading in rare cancers is difficult and largely undefined because of small sample sizes, the sheer volume of time needed to undertake on such a task, and the inherent…

The increasing efficiency and compactness of deep learning architectures, together with hardware improvements, have enabled the complex and high-dimensional modelling of medical volumetric data at higher resolutions. Recently,…

图像与视频处理 · 电气工程与系统科学 2020-02-14 Petru-Daniel Tudosiu , Thomas Varsavsky , Richard Shaw , Mark Graham , Parashkev Nachev , Sebastien Ourselin , Carole H. Sudre , M. Jorge Cardoso

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

计算机视觉与模式识别 · 计算机科学 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

One noted issue of vector-quantized variational autoencoder (VQ-VAE) is that the learned discrete representation uses only a fraction of the full capacity of the codebook, also known as codebook collapse. We hypothesize that the training…

Accurate prediction of cancer type and primary tumor site is critical for effective diagnosis, personalized treatment, and improved outcomes. Traditional models struggle with the complexity of genomic and clinical data, but quantum…

定量方法 · 定量生物学 2025-06-30 Don Roosan , Rubayat Khan , Md Rahatul Ashakin , Tiffany Khou , Saif Nirzhor , Mohammad Rifat Haider

Quantitative medical image computing (radiomics) has been widely applied to build prediction models from medical images. However, overfitting is a significant issue in conventional radiomics, where a large number of radiomic features are…

图像与视频处理 · 电气工程与系统科学 2020-01-07 Jianan Chen , Laurent Milot , Helen M. C. Cheung , Anne L. Martel

Identifying customer segments in retail banking portfolios with different risk profiles can improve the accuracy of credit scoring. The Variational Autoencoder (VAE) has shown promising results in different research domains, and it has been…

计算工程、金融与科学 · 计算机科学 2018-06-08 Rogelio Andrade Mancisidor , Michael Kampffmeyer , Kjersti Aas , Robert Jenssen

Deep neural networks with discrete latent variables offer the promise of better symbolic reasoning, and learning abstractions that are more useful to new tasks. There has been a surge in interest in discrete latent variable models, however,…

机器学习 · 计算机科学 2018-07-23 Aurko Roy , Ashish Vaswani , Arvind Neelakantan , Niki Parmar

Data-driven fault diagnostics of safety-critical systems often faces the challenge of a complete lack of labeled data associated with faulty system conditions (i.e., fault types) at training time. Since an unknown number and nature of fault…

机器学习 · 计算机科学 2020-10-01 Manuel Arias Chao , Bryan T. Adey , Olga Fink

Vector-Quantized Variational Autoencoders (VQ-VAE)[1] provide an unsupervised model for learning discrete representations by combining vector quantization and autoencoders. In this paper, we study the use of VQ-VAE for representation…

图像与视频处理 · 电气工程与系统科学 2019-03-05 Hanwei Wu , Markus Flierl

Cancer is a complex disease with significant social and economic impact. Advancements in high-throughput molecular assays and the reduced cost for performing high-quality multi-omics measurements have fuelled insights through machine…

机器学习 · 计算机科学 2022-06-28 Pedro Henrique da Costa Avelar , Roman Laddach , Sophia Karagiannis , Min Wu , Sophia Tsoka

Radio frequency (RF) communication has been an important part of civil and military communication for decades. With the increasing complexity of wireless environments and the growing number of devices sharing the spectrum, it has become…

机器学习 · 计算机科学 2024-10-25 Srihari Kamesh Kompella , Kemal Davaslioglu , Yalin E. Sagduyu , Sastry Kompella

An important challenge in emotion recognition is to develop methods that can leverage unlabeled training data. In this paper, we propose the VQ-MAE-AV model, a self-supervised multimodal model that leverages masked autoencoders to learn…

声音 · 计算机科学 2025-05-12 Samir Sadok , Simon Leglaive , Renaud Séguier

The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

量子物理 · 物理学 2021-12-24 Junde Li , Swaroop Ghosh

The vector quantization is a widely used method to map continuous representation to discrete space and has important application in tokenization for generative mode, bottlenecking information and many other tasks in machine learning. Vector…

机器学习 · 计算机科学 2024-10-15 Mingyuan Yan , Jiawei Wu , Rushi Shah , Dianbo Liu

Unsupervised learning on high-dimensional RNA-seq data can reveal molecular subtypes beyond standard labels. We combine an autoencoder-based representation with clustering and stability analysis to search for rare but reproducible genomic…

机器学习 · 计算机科学 2025-11-18 Alaa Mezghiche

The electrocardiogram (ECG) is an inexpensive and widely available tool for cardiovascular assessment. Despite its standardized format and small file size, the high complexity and inter-individual variability of ECG signals (typically a…

机器学习 · 计算机科学 2024-10-31 Christopher J. Harvey , Sumaiya Shomaji , Zijun Yao , Amit Noheria

The lack of explainability is one of the most prominent disadvantages of deep learning applications in omics. This "black box" problem can undermine the credibility and limit the practical implementation of biomedical deep learning models.…

基因组学 · 定量生物学 2021-08-19 Eloise Withnell , Xiaoyu Zhang , Kai Sun , Yike Guo

Deep Learning models encode rich semantic information in their hidden representations. However, it remains challenging to understand which parts of this information models actually rely on when making predictions. A promising line of…

机器学习 · 计算机科学 2026-02-04 Xuemin Yu , Ankur Garg , Samira Ebrahimi Kahou , Hassan Sajjad

Variational autoencoders (VAEs) are widely used deep generative models capable of learning unsupervised latent representations of data. Such representations are often difficult to interpret or control. We consider the problem of…

机器学习 · 计算机科学 2018-12-18 Jack Klys , Jake Snell , Richard Zemel