相关论文: Lab-on-a-Chip Optical Biosensor Platform: Micro Ri…
Conventional spectrometer and polarimeter systems rely on bulky optics, fundamentally limiting compact integration and hindering multi-dimensional optical sensing capabilities. Here, we propose a spectropolarimeter enabled by…
A major limitation of transient optical spectroscopy is that relatively high laser fluences are required to enable broadband, multichannel detection with acceptable signal-to-noise levels. Under typical experimental conditions, many…
We demonstrate that a near-field microwave microscope based on a transmission line resonator allows imaging in a substantially wide range of frequencies, so that the microscope properties approach those of a spatially-resolved impedance…
We present a system for molecular spectroscopy using a broadband mid-infrared laser with near infrared detection. Difference frequency generation of a Yb:fiber femtosecond laser produced a mid-infrared (MIR) source tunable from 2100-3700…
A miniaturized full-frequency encoded illumination (mini-FEI) chip is presented for high-throughput super-resolution imaging using the spatial frequency shift (SFS) effect. A tunable full SFS scheme is achieved through propagating and…
We demonstrate novel instrumentation for spontaneous Raman spectroscopy in biofluids, enabling development of a portable, automated, reliable diagnostics technique requiring minimal operator expertise to quantify disease markers. Label-free…
Magnetic resonance imaging (MRI) is a non-invasive and label-free technique widely used in medical diagnosis and life science research, and its success has benefited greatly from continuing efforts on enhancing contrast and resolution. Here…
Multi-dielectric coated coverslip can be designed to reach large optical field enhancements when working under proper illumination conditions and in total internal reflection. In an objective-based total internal reflection fluorescence…
Optical fibers are widely used in bioimaging systems as flexible endoscopes capable of low-invasive penetration inside hollow tissue cavities. Here, we report on the technique which allows magnetic resonance imaging (MRI) of hollow-core…
We present a reference-free computational wavefront sensor based on binary amplitude modulation and phase retrieval. The method employs Digital Micro-mirror Device as a programmable amplitude modulator and reconstructs the complex optical…
Integrated and fiber-packaged magnetic field sensors with a sensitivity sufficient to sense electric pulses propagating along nerves in life science applications and with a spatial resolution fine enough to resolve their propagation…
Reconfigurable photonic circuits have applications ranging from next-generation computer architectures to quantum networks, coherent radar and optical metamaterials. However, complete reconfigurability is only currently practical on…
We design and characterize a novel axilens-based diffractive optics platform that flexibly combines efficient point focusing and grating selectivity and is compatible with scalable top-down fabrication based on a 4-level phase mask…
We develop a novel hyperspectral imaging system using structured illumination in an SLM-based Michelson interferometer. In our design, we use a reflective SLM as a mirror in one of the arms of a Michelson interferometer, and scan the…
We demonstrate a fully-integrated multipurpose microwave frequency identification system on silicon-on-insulator platform. Thanks to its multipurpose features, the chip is able to identify different types of microwave signals, including…
Optical biosensors based on micro-/nano-fibers are highly valuable for probing and monitoring liquid environments and bioactivity. Most of current optical biosensors, however, are still based on glass, semiconductors, or metallic materials,…
We report a notch-shaped coplanar microwave waveguide antenna on a glass plate designed for on-chip detection of optically detected magnetic resonance (ODMR) of fluorescent nanodiamonds (NDs). A lithographically patterned thin wire at the…
We experimentally realize an optical fiber ring resonator that includes a tapered section with subwavelength-diameter waist. In this section, the guided light exhibits a significant evanescent field which allows for efficient interfacing…
In this study, we present a highly sensitive Surface Plasmon Resonance (SPR)-based biosensor integrated with a circular-lattice Photonic Crystal Fiber (PCF) for early-stage cancer detection. The proposed sensor leverages the synergy between…
Integrated photonic biosensors provide compact, highly sensitive, and label-free platforms for biochemical detection, making them attractive for on-chip and real-time sensing applications. However, their design remains challenging due to…