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Aging includes both continuous gradual decline from microscopic mechanisms together with major deficit onset events such as morbidity, disability and ultimately death. These deficit events are stochastic, obscuring the connection between…

定量方法 · 定量生物学 2025-12-25 Glen Pridham , Kenneth Rockwood , Andrew Rutenberg

How long people live depends on their health, and how it changes with age. Individual health can be tracked by the accumulation of age-related health deficits. The fraction of age-related deficits is a simple quantitative measure of human…

定量方法 · 定量生物学 2016-03-23 Swadhin Taneja , Arnold B. Mitnitski , Kenneth Rockwood , Andrew D. Rutenberg

In this article, we formulate and analyze a new non-linear mathematical model to describe the dynamics of unemployment with a discouraged working population. We consider five dynamic variables, namely, unskilled unemployed individuals,…

物理与社会 · 物理学 2026-01-13 Poushali Das , Shraddha Sachan , Mukul Chauhan , Narendra Kumar , Amit K. Verma

This paper presents a semi-quantitative mathematical model of the changes over time in the statistical distribution of well-being of individuals in a society. The model predicts that when individuals overvalue the more socially conspicuous…

物理与社会 · 物理学 2016-01-05 Chris Thron

We formulate a flexible micro-to-macro kinetic model which is able to explain the emergence of income profiles out of a whole of individual economic interactions. The model is expressed by a system of several nonlinear differential…

经济学 · 定量金融 2016-11-28 Maria Letizia Bertotti , Giovanni Modanese

Decisions to pursue higher education are not fully explained by economic incentives, with social influence and peer effects playing a crucial, yet dynamically understudied, role. This paper develops a theoretical non-linear dynamics model…

综合经济学 · 经济学 2026-04-06 Andrea Caravaggio , Marco Catola , Silvia Leoni

Urbanization promotes economy, mobility, access and availability of resources, but on the other hand, generates higher levels of pollution, violence, crime, and mental distress. The health consequences of the agglomeration of people living…

物理与社会 · 物理学 2021-02-09 Luis E. C. Rocha , Anna E. Thorson , Renaud Lambiotte

High-quality healthcare in the US can be cost-prohibitive for certain socioeconomic groups. In this paper, we examined data from the US Census and the CDC to determine the degree to which specific socioeconomic factors correlate with both…

计算机与社会 · 计算机科学 2023-05-25 Krish Khanna , Jeffrey Lu , Jay Warrier

To explore the mechanistic relationships between ageing, frailty and mortality, we developed a computational model in which possible health attributes are represented by the nodes of a complex network. Each node can be either damaged (i.e.…

种群与进化 · 定量生物学 2017-06-30 Andrew D. Rutenberg , Arnold B. Mitnitski , Spencer Farrell , Kenneth Rockwood

As the aging population grows, particularly for the baby boomer generation, the United States is witnessing a significant increase in the elderly population experiencing multifunctional disabilities. These disabilities, stemming from a…

机器学习 · 计算机科学 2024-04-09 Suiyao Chen , Xinyi Liu , Yulei Li , Jing Wu , Handong Yao

This paper investigates a nonlinear logistic model for age-structured population dynamics. The model incorporates interdependent fertility and mortality functions within a logistic framework, offering insights into stationary solutions and…

偏微分方程分析 · 数学 2025-11-24 Dragos-Patru Covei

A widely-used model for determining the long-term health impacts of public health interventions, often called a "multistate lifetable", requires estimates of incidence, case fatality, and sometimes also remission rates, for multiple…

应用统计 · 统计学 2023-03-23 Christopher Jackson , Belen Zapata-Diomedi , James Woodcock

Life's most valuable asset is health. Continuously understanding the state of our health and modeling how it evolves is essential if we wish to improve it. Given the opportunity that people live with more data about their life today than…

人工智能 · 计算机科学 2020-08-04 Nitish Nag

This paper generalizes a previously published differential equation that describes the relation between the age-specific incidence, remission, and mortality of a disease with its prevalence. The underlying model is a simple compartment…

种群与进化 · 定量生物学 2012-09-07 Ralph Brinks

This research develops a socioeconomic health index for nations through a model-based approach which incorporates spatial dependence and examines the impact of a policy through a causal modeling framework. As the gross domestic product…

应用统计 · 统计学 2019-11-11 F. Swen Kuh , Grace S. Chiu , Anton H. Westveld

Opinion dynamics of a group of individuals is the change in the members' opinions through mutual interaction with each other. The related literature contains works in which the dynamics is modeled as a continuous system, of which behavioral…

动力系统 · 数学 2018-01-01 F. Ataş , A. Demirci , C. Özemir

Relevant events in a three state illness-death model (IDM) of a chronic disease are the diagnosis of the disease and death with or without the disease. In this article a simulation framework for populations moving in the IDM is presented.…

种群与进化 · 定量生物学 2013-01-01 Ralph Brinks

Dynamic microsimulation has long been recognized as a powerful tool for policy analysis, but in fact most major health policy simulations lack path dependency, a critical feature for evaluating policies that depend on accumulated outcomes…

应用统计 · 统计学 2025-06-04 Adrienne M. Propp , Raffaele Vardavas , Carter C. Price , Kandice A. Kapinos

Modeling how individuals evolve over time is a fundamental problem in the natural and social sciences. However, existing datasets are often cross-sectional with each individual observed only once, making it impossible to apply traditional…

Organisms from microbes to humans engage in a variety of social behaviors, which affect fitness in complex, often nonlinear ways. The question of how these behaviors evolve has consequences ranging from antibiotic resistance to human…

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