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Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

神经元与认知 · 定量生物学 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

机器学习 · 计算机科学 2025-11-11 Richard Hou , Shengpu Tang , Wei Jin

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

图像与视频处理 · 电气工程与系统科学 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

In many real-world scenarios, data to train machine learning models become available over time. However, neural network models struggle to continually learn new concepts without forgetting what has been learnt in the past. This phenomenon…

机器学习 · 计算机科学 2022-06-29 Beyza Ermis , Giovanni Zappella , Martin Wistuba , Aditya Rawal , Cedric Archambeau

Early diagnosis of Alzheimer's disease (AD) remains a major challenge due to the subtle and temporally irregular progression of structural brain changes in the prodromal stages. Existing deep learning approaches require large longitudinal…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Maxx Richard Rahman , Mostafa Hammouda , Wolfgang Maass

Alzheimer's Disease (AD) is a severe brain disorder, destroying memories and brain functions. AD causes chronically, progressively, and irreversibly cognitive declination and brain damages. The reliable and effective evaluation of early…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Kuo Yang , Emad A. Mohammed

Transformers have reached remarkable success in sequence modeling. However, these models have efficiency issues as they need to store all the history token-level representations as memory. We present Memformer, an efficient neural network…

计算与语言 · 计算机科学 2022-04-14 Qingyang Wu , Zhenzhong Lan , Kun Qian , Jing Gu , Alborz Geramifard , Zhou Yu

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

图像与视频处理 · 电气工程与系统科学 2025-08-19 Siva Manohar Reddy Kesu , Neelam Sinha , Hariharan Ramasangu , Thomas Gregor Issac

Long-term weather forecasting is critical for socioeconomic planning and disaster preparedness. While recent approaches employ finetuning to extend prediction horizons, they remain constrained by the issues of catastrophic forgetting, error…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Hao Chen , Tao Han , Jie Zhang , Song Guo , Fenghua Ling , Lei Bai

Accurate prediction of clinical scores is critical for early detection and prognosis of Alzheimers disease (AD). While existing approaches primarily focus on forecasting the ADAS-Cog global score, they often overlook the predictive value of…

The accurate prediction of survival times for patients with severe diseases remains a critical challenge despite recent advances in artificial intelligence. This study introduces "SurvTimeSurvival: Survival Analysis On Patients With…

机器学习 · 计算机科学 2023-11-17 Hung Le , Ong Eng-Jon , Bober Miroslaw

Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…

图像与视频处理 · 电气工程与系统科学 2025-01-29 Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Chao Cao , Tong Chen , Minheng Chen , Yan Zhuang , Tianming Liu , Dajiang Zhu

Accurate diagnosis of Alzheimer's disease (AD) is essential for enabling timely intervention and slowing disease progression. Multimodal diagnostic approaches offer considerable promise by integrating complementary information across…

计算机视觉与模式识别 · 计算机科学 2025-10-30 Yujie Nie , Jianzhang Ni , Yonglong Ye , Yuan-Ting Zhang , Yun Kwok Wing , Xiangqing Xu , Xin Ma , Lizhou Fan

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Transfer learning has gained attention in medical image analysis due to limited annotated 3D medical datasets for training data-driven deep learning models in the real world. Existing 3D-based methods have transferred the pre-trained models…

计算机视觉与模式识别 · 计算机科学 2021-04-29 Eunji Jun , Seungwoo Jeong , Da-Woon Heo , Heung-Il Suk

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…

Computational models that forecast the progression of Alzheimer's disease at the patient level are extremely useful tools for identifying high risk cohorts for early intervention and treatment planning. The state-of-the-art work in this…

机器学习 · 计算机科学 2019-12-30 Surya Teja Devarakonda , Joie Yeahuay Wu , Yi Ren Fung , Madalina Fiterau

Transformer-based models have emerged as promising tools for time series forecasting. However, these model cannot make accurate prediction for long input time series. On the one hand, they failed to capture global dependencies within time…

机器学习 · 计算机科学 2023-08-16 YanJun Zhao , Ziqing Ma , Tian Zhou , Liang Sun , Mengni Ye , Yi Qian

Although transformer-based methods have achieved great success in multi-scale temporal pattern interaction modeling, two key challenges limit their further development: (1) Individual time points contain less semantic information, and…

机器学习 · 计算机科学 2024-11-01 Zongjiang Shang , Ling Chen , Binqing wu , Dongliang Cui

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, primarily affecting the elderly population and leading to significant cognitive decline. This decline manifests in various mental faculties such as attention,…

机器学习 · 计算机科学 2025-04-22 Emine Akpinar
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