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Digitized histopathology glass slides, known as Whole Slide Images (WSIs), are often several gigapixels large and contain sensitive metadata information, which makes distributed processing unfeasible. Moreover, artifacts in WSIs may result…

计算工程、金融与科学 · 计算机科学 2023-09-14 Yuandou Wang , Neel Kanwal , Kjersti Engan , Chunming Rong , Zhiming Zhao

A Whole Slide Image (WSI) is a high-resolution digital image created by scanning an entire glass slide containing a biological specimen, such as tissue sections or cell samples, at multiple magnifications. These images are digitally…

Histology slide digitization is becoming essential for telepathology (remote consultation), knowledge sharing (education), and using the state-of-the-art artificial intelligence algorithms (augmented/automated end-to-end clinical…

图像与视频处理 · 电气工程与系统科学 2024-05-15 Talat Zehra , Joseph Marino , Wendy Wang , Grigoriy Frantsuzov , Saad Nadeem

Convolutional neural networks, the state of the art for image segmentation, have been successfully applied to histology images by many computational researchers. However, the translatability of this technology to clinicians and biological…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Brendon Lutnick , David Manthey , Pinaki Sarder

In this paper, scalable Whole Slide Imaging (sWSI), a novel high-throughput, cost-effective and robust whole slide imaging system on both Android and iOS platforms is introduced and analyzed. With sWSI, most mainstream smartphone connected…

生物物理 · 物理学 2017-04-05 Shuoxin Ma , Tan Wang

We present a novel diffusion-based approach to generate synthetic histopathological Whole Slide Images (WSIs) at an unprecedented gigapixel scale. Synthetic WSIs have many potential applications: They can augment training datasets to…

图像与视频处理 · 电气工程与系统科学 2023-11-15 Robert Harb , Thomas Pock , Heimo Müller

Objective: The exchange of health-related data is subject to regional laws and regulations, such as the General Data Protection Regulation (GDPR) in the EU or the Health Insurance Portability and Accountability Act (HIPAA) in the United…

计算机与社会 · 计算机科学 2024-01-24 Tom Bisson , Michael Franz , Isil Dogan O , Daniel Romberg , Christoph Jansen , Peter Hufnagl , Norman Zerbe

The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

Recent advancements in whole slide imaging (WSI) have moved pathology closer to digital practice. Existing systems require precise mechanical control and the cost is prohibitive for most individual pathologists. Here we report a low-cost…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Chengfei Guo , Zichao Bian , Shaowei Jiang , Michael Murphy , Jiakai Zhu , Ruihai Wang , Pengming Song , Xiaopeng Shao , Yongbing Zhang , Guoan Zheng

Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

图像与视频处理 · 电气工程与系统科学 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

Whole slide images (WSI) are microscopy images of stained tissue slides routinely prepared for diagnosis and treatment selection in medical practice. WSI are very large (gigapixel size) and complex (made of up to millions of cells). The…

计算机视觉与模式识别 · 计算机科学 2022-12-08 Tristan Lazard , Marvin Lerousseau , Etienne Decencière , Thomas Walter

Whole slide imaging (WSI) is an emerging technology for digital pathology. The process of autofocusing is the main influence of the performance of WSI. Traditional autofocusing methods either are time-consuming due to repetitive mechanical…

图像与视频处理 · 电气工程与系统科学 2020-03-17 Qiang Li , Xianming Liu , Kaige Han , Cheng Guo , Xiangyang Ji , Xiaolin Wu

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extraction pipelines based on tools like CellProfiler often involve…

图像与视频处理 · 电气工程与系统科学 2025-01-13 Yuechen Yang , Yu Wang , Tianyuan Yao , Ruining Deng , Mengmeng Yin , Shilin Zhao , Haichun Yang , Yuankai Huo

Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

图像与视频处理 · 电气工程与系统科学 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

计算机视觉与模式识别 · 计算机科学 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Background: The use of whole slide imaging (WSI) for digital pathology has recently been cleared for primary diagnosis in the US. A conventional WSI system scans the tissue slide to different positions and acquires the digital images. In a…

图像与视频处理 · 电气工程与系统科学 2019-07-26 Shaowei Jiang , Zichao Bian , Xizhi Huang , Pengming Song , He Zhang , Yongbing Zhang , Guoan Zheng

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

The expanding adoption of digital pathology has enabled the curation of large repositories of histology whole slide images (WSIs), which contain a wealth of information. Similar pathology image search offers the opportunity to comb through…

计算机视觉与模式识别 · 计算机科学 2021-07-30 Chengkuan Chen , Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Andrew J. Schaumberg , Faisal Mahmood
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