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An important part of Digital Pathology is the analysis of multiple digitised whole slide images from differently stained tissue sections. It is common practice to mount consecutive sections containing corresponding microscopic structures on…

计算机视觉与模式识别 · 计算机科学 2018-11-06 Thomas Lampert , Odyssée Merveille , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Lung adenocarcinoma is a morphologically heterogeneous disease, characterized by five primary histologic growth patterns. The quantity of these patterns can be related to tumor behavior and has a significant impact on patient prognosis. In…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , Nasir Rajpoot , Shan E Ahmed Raza

With the advanced imaging technology, digital pathology imaging of tumor tissue slides is becoming a routine clinical procedure for cancer diagnosis. This process produces massive imaging data that capture histological details in high…

应用统计 · 统计学 2020-12-10 Esteban Fernández Morales , Cong Zhang , Guanghua Xiao , Chul Moon , Qiwei Li

Digital pathology, augmented by artificial intelligence (AI), holds significant promise for improving the workflow of pathologists. However, challenges such as the labor-intensive annotation of whole slide images (WSIs), high computational…

图像与视频处理 · 电气工程与系统科学 2025-04-18 Walid Rehamnia , Alexandra Getmanskaya , Evgeniy Vasilyev , Vadim Turlapov

Digital pathology (DP) is a new research area which falls under the broad umbrella of health informatics. Owing to its potential for major public health impact, in recent years DP has been attracting much research attention. Nevertheless, a…

图像与视频处理 · 电气工程与系统科学 2019-03-12 Xingzhi Yue , Neofytos Dimitriou , Ognjen Arandjelovic

Prostate cancer is the most prevalent cancer among men in Western countries, with 1.1 million new diagnoses every year. The gold standard for the diagnosis of prostate cancer is a pathologists' evaluation of prostate tissue. To potentially…

图像与视频处理 · 电气工程与系统科学 2020-10-23 Hans Pinckaers , Wouter Bulten , Jeroen van der Laak , Geert Litjens

Whole Slide Images (WSIs) present a challenging computer vision task due to their gigapixel size and presence of numerous artefacts. Yet they are a valuable resource for patient diagnosis and stratification, often representing the gold…

计算机视觉与模式识别 · 计算机科学 2023-10-05 Amaya Gallagher-Syed , Luca Rossi , Felice Rivellese , Costantino Pitzalis , Myles Lewis , Michael Barnes , Gregory Slabaugh

Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

计算机视觉与模式识别 · 计算机科学 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

Automated whole slide image (WSI) tagging has become a growing demand due to the increasing volume and diversity of WSIs collected nowadays in histopathology. Various methods have been studied to classify WSIs with single tags but none of…

计算机视觉与模式识别 · 计算机科学 2019-07-05 Weijian Li , Viet-Duy Nguyen , Haofu Liao , Matt Wilder , Ke Cheng , Jiebo Luo

This paper presents a new approach for classifying 2D histopathology patches using few-shot learning. The method is designed to tackle a significant challenge in histopathology, which is the limited availability of labeled data. By applying…

图像与视频处理 · 电气工程与系统科学 2024-03-12 Aymen Sadraoui , Ségolène Martin , Eliott Barbot , Astrid Laurent-Bellue , Jean-Christophe Pesquet , Catherine Guettier , Ismail Ben Ayed

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in…

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

图像与视频处理 · 电气工程与系统科学 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

计算机视觉与模式识别 · 计算机科学 2023-09-06 Ruijie Zhang , Qiaozhe Zhang , Yingzhuang Liu , Hao Xin , Yan Liu , Xinggang Wang

Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

计算机视觉与模式识别 · 计算机科学 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

计算机视觉与模式识别 · 计算机科学 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

The Wireless Capsule Endoscopy (WCE) is becoming a popular way of screening gastrointestinal system diseases and cancer. However, the time-consuming process in inspecting WCE data limits its applications and increases the cost of…

计算机视觉与模式识别 · 计算机科学 2018-09-10 Xiaolu Zhang , Shiwan Zhao , Lingxi Xie

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim