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Background: Providing appropriate care for people suffering from COVID-19, the disease caused by the pandemic SARS-CoV-2 virus is a significant global challenge. Many individuals who become infected have pre-existing conditions that may…

The development of therapeutic targets for COVID-19 treatment is based on the understanding of the molecular mechanism of pathogenesis. The identification of genes and proteins involved in the infection mechanism is the key to shed out…

生物大分子 · 定量生物学 2021-05-19 Jayanta Kumar Das , Swarup Roy , Pietro Hiram Guzzi

In 2019, the world faced a new challenge: a COVID-19 disease caused by the novel coronavirus, SARS-CoV-2. The virus rapidly spread across the globe, leading to a high rate of mortality, which prompted health organizations to take measures…

图像与视频处理 · 电气工程与系统科学 2024-08-08 Kavian Khanjani , Seyed Rasoul Hosseini , Hamid Taheri , Shahrzad Shashaani , Mohammad Teshnehlab

Motivation: With the aim to amplify and make sense of interactions of virus-human proteins in the case of SARS-CoV-2, we performed a structural analysis of the network of protein interactions obtained from the integration of three sources:…

分子网络 · 定量生物学 2020-09-15 Beatriz Luna , Marcelino Ramírez , Edgardo Galán

A molecular and cellular understanding of how SARS-CoV-2 variably infects and causes severe COVID-19 remains a bottleneck in developing interventions to end the pandemic. We sought to use deep learning to study the biology of SARS-CoV-2…

机器学习 · 计算机科学 2020-12-16 Arijit Sehanobish , Neal G. Ravindra , David van Dijk

COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the understanding of the molecular mechanisms involved in…

The world has witnessed unprecedented human and economic loss from the COVID-19 disease, caused by the novel coronavirus SARS-CoV-2. Extensive research is being conducted across the globe to identify therapeutic agents against the…

Until now, Coronavirus SARS-CoV-2 has caused more than 850,000 deaths and infected more than 27 million individuals in over 120 countries. Besides principal polymerase chain reaction (PCR) tests, automatically identifying positive samples…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Duy M. H. Nguyen , Duy M. Nguyen , Huong Vu , Binh T. Nguyen , Fabrizio Nunnari , Daniel Sonntag

COVID-19 has created a global pandemic with high morbidity and mortality in 2020. Novel coronavirus (nCoV), also known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), is responsible for this deadly disease. International…

COVID-19 is a devastating respiratory and inflammatory illness caused by a new coronavirus that is rapidly spreading throughout the human population. Over the past 6 months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the…

There have been more than 850,000 confirmed cases and over 48,000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone.…

定量方法 · 定量生物学 2020-05-25 Xiangxiang Zeng , Xiang Song , Tengfei Ma , Xiaoqin Pan , Yadi Zhou , Yuan Hou , Zheng Zhang , George Karypis , Feixiong Cheng

The SARS-CoV-2 coronavirus is the cause of the COVID-19 disease in humans. Like many coronaviruses, it can adapt to different hosts and evolve into different lineages. It is well-known that the major SARS-CoV-2 lineages are characterized by…

机器学习 · 计算机科学 2022-11-23 Sarwan Ali

Long COVID is a multisystem condition characterized by persistent symptoms such as fatigue, cognitive impairment, and systemic inflammation, following COVID-19 infection, yet its mechanisms remain poorly understood. In this study, we…

分子网络 · 定量生物学 2025-01-30 Jaesub Park , Woochang Hwang , Seokjun Lee , Hyun Chang Lee , Méabh MacMahon , Matthias Zilbauer , Namshik Han

The recent global pandemic of Coronavirus Disease 2019 (COVID-19) caused by the new coronavirus SARS-CoV-2 presents an urgent need for new therapeutic candidates. Many efforts have been devoted to screening existing drug libraries with the…

The Coronavirus Disease (COVID-19) has affected 1.8 million people and resulted in more than 110,000 deaths as of April 12, 2020. Several studies have shown that tomographic patterns seen on chest Computed Tomography (CT), such as…

Covid-19 infection, which spread to the whole world in December 2019 and is still active, caused more than 250 thousand deaths in the world today. Researches on this subject have been focused on analyzing the genetic structure of the virus,…

机器学习 · 计算机科学 2023-04-25 Selcuk Yazar

With the prevailing efforts to combat the coronavirus disease 2019 (COVID-19) pandemic, there are still uncertainties that are yet to be discovered about its spread, future impact, and resurgence. In this paper, we present a three-stage…

机器学习 · 统计学 2024-06-19 Oluwaseun T. Ajayi , Yu Cheng

The COVID-19 (coronavirus) is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in mid-December 2019 in the Hubei province of Wuhan, China and by now has spread…

图像与视频处理 · 电气工程与系统科学 2022-01-26 Aditya Saxena , Shamsheer Pal Singh

Currently, the number of patients with COVID-19 has significantly increased. Thus, there is an urgent need for developing treatments for COVID-19. Drug repurposing, which is the process of reusing already-approved drugs for new medical…

定量方法 · 定量生物学 2020-08-13 Yonghyun Nam , Jae-Seung Yun , Seung Mi Lee , Ji Won Park , Ziqi Chen , Brian Lee , Anurag Verma , Xia Ning , Li Shen , Dokyoon Kim

Corona VIrus Disease abbreviated as COVID-19 is a novel virus which is initially identified in Wuhan of China in December of 2019 and now this deadly disease has spread all over the world. According to World Health Organization (WHO), a…

机器学习 · 计算机科学 2023-08-10 Mamata Das , P. J. A. Alphonse , Selvakumar K
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