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相关论文: Two-stage matching-adjusted indirect comparison

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Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

统计方法学 · 统计学 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

In this commentary, we highlight the importance of: (1) carefully considering and clarifying whether a marginal or conditional treatment effect is of interest in a population-adjusted indirect treatment comparison; and (2) developing…

统计方法学 · 统计学 2021-11-05 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

A bidirectional integrated sensing and communication (ISAC) system is proposed, in which a pair of transceivers carry out two-way communication and mutual sensing. Both full-duplex and half-duplex operations in narrowband and wideband…

信息论 · 计算机科学 2024-01-05 Zhaolin Wang , Xidong Mu , Yuanwei Liu

To estimate the causal effect of treatments that vary over time from observational data, one must adjust for time-varying confounding. A common procedure to address confounding is the use of inverse probability of treatment weighting…

统计方法学 · 统计学 2025-01-22 Wouter M. R. Kant , Jesse H. Krijthe

In the setting of multi-armed trials, adaptive designs are a popular way to increase estimation efficiency, identify optimal treatments, or maximize rewards to individuals. Recent work has considered the case of estimating the effects of K…

统计方法学 · 统计学 2026-02-10 Evan T. R. Rosenman , Kristen B. Hunter

Propensity score matching (PSM) and augmented inverse propensity weighting (AIPW) are widely used in observational studies to estimate causal effects. The two approaches present complementary features. The AIPW estimator is doubly robust…

统计方法学 · 统计学 2025-12-12 Tanchumin Xu , Yunshu Zhang , Shu Yang

It is common to conduct causal inference in matched observational studies by proceeding as though treatment assignments within matched sets are assigned uniformly at random and using this distribution as the basis for inference. This…

统计方法学 · 统计学 2023-11-14 Samuel D. Pimentel , Yaxuan Huang

Statistical matching methods are widely used in the social and health sciences to estimate causal effects using observational data. Often the objective is to find comparable groups with similar covariate distributions in a dataset, with the…

应用统计 · 统计学 2021-01-19 Felix Bestehorn , Maike Bestehorn , Christian Kirches

Sequential multiple assignment randomized trials mimic the actual treatment processes experienced by physicians and patients in clinical settings and inform the comparative effectiveness of dynamic treatment regimes. In such trials,…

统计方法学 · 统计学 2025-04-07 Zi Wang , Yu Cheng , Abdus S. Wahed

Magnetic Resonance Imaging (MRI) is instrumental in clinical diagnosis, offering diverse contrasts that provide comprehensive diagnostic information. However, acquiring multiple MRI contrasts is often constrained by high costs, long…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Sanuwani Dayarathna , Kh Tohidul Islam , Bohan Zhuang , Guang Yang , Jianfei Cai , Meng Law , Zhaolin Chen

When investigators seek to estimate causal effects, they often assume that selection into treatment is based only on observed covariates. Under this identification strategy, analysts must adjust for observed confounders. While basic…

应用统计 · 统计学 2019-01-09 Luke Keele , Dylan Small

Aims: Combinations of treatments can offer additional benefit over the treatments individually. However, trials of these combinations are lower priority than the development of novel therapies, which can restrict funding, timelines and…

Tail Averaging improves on Polyak averaging's non-asymptotic behaviour by excluding a number of leading iterates of stochastic optimization from its calculations. In practice, with a finite number of optimization steps and a learning rate…

机器学习 · 统计学 2023-04-18 Gábor Melis

We combine a refined version of two-point step-size adaptation with the covariance matrix adaptation evolution strategy (CMA-ES). Additionally, we suggest polished formulae for the learning rate of the covariance matrix and the…

神经与进化计算 · 计算机科学 2008-12-18 Nikolaus Hansen

Causal mediation analysis (CMA) is a powerful method to dissect the total effect of a treatment into direct and mediated effects within the potential outcome framework. This is important in many scientific applications to identify the…

机器学习 · 计算机科学 2023-06-14 Ziyang Jiang , Yiling Liu , Michael H. Klein , Ahmed Aloui , Yiman Ren , Keyu Li , Vahid Tarokh , David Carlson

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the presence of high-dimensional confounding,…

统计方法学 · 统计学 2025-08-29 Susan Ellul , Stijn Vansteelandt , John B. Carlin , Margarita Moreno-Betancur

We propose a method to reduce variance in treatment effect estimates in the setting of high-dimensional data. In particular, we introduce an approach for learning a metric to be used in matching treatment and control groups. The metric…

应用统计 · 统计学 2017-12-15 Jonathan Bates , Alexander Cloninger

Background: It has long been advised to account for baseline covariates in the analysis of confirmatory randomised trials, with the main statistical justifications being that this increases power and, when a randomisation scheme balanced…

统计方法学 · 统计学 2021-12-09 Tim P. Morris , A. Sarah Walker , Elizabeth J. Williamson , Ian R. White

A key feature of determinantal sampling designs is their capacity to provide known and parametrisable inclusion probabilities at any order. This paper aims to demonstrate how to effectively leverage this characteristic, highlighting its…

统计方法学 · 统计学 2025-08-27 Vincent Loons

To estimate casual treatment effects, we propose a new matching approach based on the reduced covariates obtained from sufficient dimension reduction. Compared to the original covariates and the propensity score, which are commonly used for…

统计方法学 · 统计学 2017-02-03 Wei Luo , Yeying Zhu
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