相关论文: Controlling the spontaneous firing behavior of a n…
Brain activities are featured by spatially distributed neural clusters of coherent firings and a spontaneous switching of the clusters between the synchrony and asynchrony states. Evidences from {\it in vivo} experiments suggest that…
A mathematical model of a spiking neuron network accompanied by astrocytes is considered. The network is composed of excitatory and inhibitory neurons with synaptic connections supplied by a memristor-based model of plasticity. Another…
We propose a new mean-field model of brain rhythms governed by astrocytes. This theoretical framework describes how astrocytes can regulate neuronal activity and contribute to the generation of brain rhythms. The model describes at the…
The brain consists not only of neurons but also of non-neuronal cells, including astrocytes. Recent discoveries in neuroscience suggest that astrocytes directly regulate neuronal activity by releasing gliotransmitters such as glutamate. In…
Astrocytes are a ubiquitous and enigmatic type of non-neuronal cell and are found in the brain of all vertebrates. While traditionally viewed as being supportive of neurons, it is increasingly recognized that astrocytes may play a more…
The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons…
The investigation of the neuronal environment allows us to better understand the activity of a cerebral region as a whole. The recent experimental evidences of the presence of transporters for glutamate and GABA in both neuronal and…
We describe a simple conductance-based model neuron that includes intra- and extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is…
We report the first results of simulating the coupling of neuronal, astrocyte, and cerebrovascular activity. It is suggested that the dynamics of the system is different from systems that only include neurons. In the neuron-vascular…
The onset of regular bursts in a group of irregularly bursting neurons with different individual properties is one of the most interesting dynamical properties found in neurobiological systems. In this paper we show how synchronization…
Mathematical model of spiking neuron network (SNN) supplied by astrocytes is investigated. The astrocytes are specific type of brain cells which are not electrically excitable but inducing chemical modulations of neuronal firing. We…
Network architecture forms a critical constraint on neuronal function. Here we examine the role of structural autapses, when a neuron synapses onto itself, in driving network-wide bursting behavior. Using a simple spiking model of neuronal…
Traditional artificial neural networks take inspiration from biological networks, using layers of neuron-like nodes to pass information for processing. More realistic models include spiking in the neural network, capturing the electrical…
The Integrated Information is a quantitative measure from information theory how tightly all parts of a system are interconnected in terms of information exchange. In this study we show that astrocyte, playing an important role in…
We study in this paper the effect of an unique initial stimulation on random recurrent networks of leaky integrate and fire neurons. Indeed given a stochastic connectivity this so-called spontaneous mode exhibits various non trivial…
Within the complex neuroarchitecture of the brain, astrocytes play crucial roles in development, structure, and metabolism. These cells regulate neural activity through tripartite synapses, directly impacting cognitive processes such as…
The study of balanced networks of excitatory and inhibitory neurons has led to several open questions. On the one hand it is yet unclear whether the asynchronous state observed in the brain is autonomously generated, or if it results from…
Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the…
Understanding the role of astrocytes in brain computation is a nascent challenge, promising immense rewards, in terms of new neurobiological knowledge that can be translated into artificial intelligence. In our ongoing effort to identify…
Finding the origin of slow and infra-slow oscillations could reveal or explain brain mechanisms in health and disease. Here, we present a biophysically constrained computational model of a neural network where the inclusion of astrocytes…