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The understanding of the mechanisms of SARS-CoV-2 evolution and transmission is one of the greatest challenges of our time. By integrating artificial intelligence (AI), viral genomes isolated from patients, tens of thousands of mutational…

定量方法 · 定量生物学 2022-09-08 Guo-Wei Wei

Accurate and reliable forecasting of emerging dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants enables policymakers and vaccine makers to get prepared for future waves of infections. The last three waves of…

种群与进化 · 定量生物学 2022-10-19 Jiahui Chen , Rui Wang , Yuta Hozumi , Gengzhuo Liu , Yuchi Qiu , Xiaoqi Wei , Guo-Wei Wei

The integration of machine learning methods into bioinformatics provides particular benefits in identifying how therapeutics effective in one context might have utility in an unknown clinical context or against a novel pathology. We aim to…

机器学习 · 计算机科学 2020-06-29 Semih Cantürk , Aman Singh , Patrick St-Amant , Jason Behrmann

The severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) caused a global pandemic and immensely affected the global economy. Accurate, cost-effective, and quick tests have proven substantial in identifying infected people and…

The latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant Omicron (B.1.1.529) has ushered panic responses around the world due to its contagious and vaccine escape mutations. The essential infectivity and antibody…

定量方法 · 定量生物学 2021-12-03 Jiahui Chen , Rui Wang , Nancy Benovich Gilby , Guo-Wei Wei

The outbreak of COVID-19 caused millions of deaths worldwide, and the number of total infections is still rising. It is necessary to identify some potentially effective drugs that can be used to prevent the development of severe symptoms or…

分子网络 · 定量生物学 2022-09-07 Fan Hu , Jiaxin Jiang , Peng Yin

Effective, sensitive, and reliable diagnostic reagents are of paramount importance for combating the ongoing coronavirus disease 2019 (COVID-19) pandemic at a time there is no preventive vaccine nor specific drug available for severe acute…

基因组学 · 定量生物学 2020-05-06 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Computer-aided diagnosis (CAD) systems stand out as potent aids for physicians in identifying the novel Coronavirus Disease 2019 (COVID-19) through medical imaging modalities. In this paper, we showcase the integration and reliable and fast…

图像与视频处理 · 电气工程与系统科学 2024-03-13 Demetris Gerogiannis , Anastasios Arsenos , Dimitrios Kollias , Dimitris Nikitopoulos , Stefanos Kollias

The world has witnessed unprecedented human and economic loss from the COVID-19 disease, caused by the novel coronavirus SARS-CoV-2. Extensive research is being conducted across the globe to identify therapeutic agents against the…

Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected near 5 million people and led to over 0.3 million deaths. Currently, there is no specific anti-SARS-CoV-2…

生物大分子 · 定量生物学 2020-05-21 Kaifu Gao , Duc Duy Nguyen , Jiahui Chen , Rui Wang , Guo-Wei Wei

Mutating variants of COVID-19 have been reported across many US states since 2021. In the fight against COVID-19, it has become imperative to study the heterogeneity in the time-varying transmission rates for each variant in the presence of…

种群与进化 · 定量生物学 2022-05-17 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

In 2019, the world faced a new challenge: a COVID-19 disease caused by the novel coronavirus, SARS-CoV-2. The virus rapidly spread across the globe, leading to a high rate of mortality, which prompted health organizations to take measures…

图像与视频处理 · 电气工程与系统科学 2024-08-08 Kavian Khanjani , Seyed Rasoul Hosseini , Hamid Taheri , Shahrzad Shashaani , Mohammad Teshnehlab

COVID-19 is a devastating respiratory and inflammatory illness caused by a new coronavirus that is rapidly spreading throughout the human population. Over the past 6 months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the…

The recent outbreak of SARS COV-2 gave us a unique opportunity to study for a non interventional and sustainable AI solution. Lung disease remains a major healthcare challenge with high morbidity and mortality worldwide. The predominant…

图像与视频处理 · 电气工程与系统科学 2021-01-14 Razib Mustafiz , Khaled Mohsin

With the rapid spread of the novel coronavirus (COVID-19) across the globe and its continuous mutation, it is of pivotal importance to design a system to identify different known (and unknown) variants of SARS-CoV-2. Identifying particular…

定量方法 · 定量生物学 2021-10-13 Sarwan Ali , Bikram Sahoo , Naimat Ullah , Alexander Zelikovskiy , Murray Patterson , Imdadullah Khan

Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are…

Under the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient and specific therapies are urgently needed. Compared with traditional small-molecular drugs, antibody therapies are relatively easy to develop and as…

生物大分子 · 定量生物学 2020-06-19 Jiahui Chen , Kaifu Gao , Rui Wang , Duc Duy Nguyen , Guo-Wei Wei

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectivity is a major concern in coronavirus disease 2019 (COVID-19) prevention and economic reopening. However, rigorous determination of SARS-COV-2 infectivity is essentially…

生物大分子 · 定量生物学 2020-06-01 Jiahui Chen , Rui Wang , Menglun Wang , Guo-Wei Wei

Coronavirus disease 2019 (COVID-19) has impacted almost every part of human life worldwide, posing a massive threat to human health. There is no specific drug for COVID-19, highlighting the urgent need for the development of effective…

基因组学 · 定量生物学 2020-12-07 Zhihan Wang , Kai Guo , Pan Gao , Qinqin Pu , Min Wu , Changlong Li , Junguk Hur
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