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Segmentation of pathological images is essential for accurate disease diagnosis. The quality of manual labels plays a critical role in segmentation accuracy; yet, in practice, the labels between pathologists could be inconsistent, thus…

图像与视频处理 · 电气工程与系统科学 2021-04-07 Li Xiao , Yinhao Li , Luxi Qv , Xinxia Tian , Yijie Peng , S. Kevin Zhou

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

In a Cox model, the partial likelihood, as the product of a series of conditional probabilities, is used to estimate the regression coefficients. In practice, those conditional probabilities are approximated by risk score ratios based on a…

统计方法学 · 统计学 2025-02-27 Youngjin Cho , Yili Hong , Pang Du

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

图像与视频处理 · 电气工程与系统科学 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Acquiring large-scale medical image data, necessary for training machine learning algorithms, is frequently intractable, due to prohibitive expert-driven annotation costs. Recent datasets extracted from hospital archives, e.g., DeepLesion,…

计算机视觉与模式识别 · 计算机科学 2020-11-24 Jinzheng Cai , Adam P. Harrison , Youjing Zheng , Ke Yan , Yuankai Huo , Jing Xiao , Lin Yang , Le Lu

Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images,…

计算机视觉与模式识别 · 计算机科学 2019-08-22 Simon Andermatt , Antal Horváth , Simon Pezold , Philippe Cattin

We propose a model for the joint segmentation of the liver and liver lesions in computed tomography (CT) volumes. We build the model from two fully convolutional networks, connected in tandem and trained together end-to-end. We evaluate our…

计算机视觉与模式识别 · 计算机科学 2018-08-14 Eugene Vorontsov , An Tang , Chris Pal , Samuel Kadoury

In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

图像与视频处理 · 电气工程与系统科学 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

Longitudinal lesion analysis is crucial for oncological care, yet automated tools often struggle with temporal consistency. While universal lesion segmentation models have advanced, they are typically designed for single time points. This…

图像与视频处理 · 电气工程与系统科学 2025-07-28 Niels Rocholl , Ewoud Smit , Mathias Prokop , Alessa Hering

The accurate segmentation of multiple types of lesions from adjacent tissues in medical images is significant in clinical practice. Convolutional neural networks (CNNs) based on the coarse-to-fine strategy have been widely used in this…

图像与视频处理 · 电气工程与系统科学 2021-10-12 Xiangyu Zhao , Peng Zhang , Fan Song , Chenbin Ma , Guangda Fan , Yangyang Sun , Youdan Feng , Guanglei Zhang

The prediction and selection of lesion features are two important tasks in voxel-based neuroimage analysis. Existing multivariate learning models take two tasks equivalently and optimize simultaneously. However, in addition to lesion…

计算机视觉与模式识别 · 计算机科学 2020-07-20 Xinwei Sun , Wenjing Han , Lingjing Hu , Yuan Yao , Yizhou Wang

Brain lesions, including stroke and tumours, have a high degree of variability in terms of location, size, intensity and form, making automatic segmentation difficult. We propose an improvement to existing segmentation methods by exploiting…

图像与视频处理 · 电气工程与系统科学 2019-07-22 Kevin Raina , Uladzimir Yahorau , Tanya Schmah

Brain tissue segmentation from multimodal MRI is a key building block of many neuroimaging analysis pipelines. Established tissue segmentation approaches have, however, not been developed to cope with large anatomical changes resulting from…

图像与视频处理 · 电气工程与系统科学 2020-11-05 Reuben Dorent , Thomas Booth , Wenqi Li , Carole H. Sudre , Sina Kafiabadi , Jorge Cardoso , Sebastien Ourselin , Tom Vercauteren

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

图像与视频处理 · 电气工程与系统科学 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

The focus of modern biomedical studies has gradually shifted to explanation and estimation of joint effects of high dimensional predictors on disease risks. Quantifying uncertainty in these estimates may provide valuable insight into…

统计方法学 · 统计学 2021-03-09 Zhe Fei , Yi Li

White matter hyperintensities (WMH) are a hallmark of cerebrovascular disease and multiple sclerosis. Automated WMH segmentation methods enable quantitative analysis via estimation of total lesion load, spatial distribution of lesions, and…

图像与视频处理 · 电气工程与系统科学 2024-03-22 Xiaoling Hu , Annabel Sorby-Adams , Frederik Barkhof , W Taylor Kimberly , Oula Puonti , Juan Eugenio Iglesias

There has been growing research interest in using deep learning based method to achieve fully automated segmentation of lesion in Positron emission tomography computed tomography(PET CT) scans for the prognosis of various cancers. Recent…

图像与视频处理 · 电气工程与系统科学 2022-09-19 Jia Zhang , Yukun Huang , Zheng Zhang , Yuhang Shi

We propose a novel convolutional neural network for lesion detection from weak labels. Only a single, global label per image - the lesion count - is needed for training. We train a regression network with a fully convolutional architecture…

计算机视觉与模式识别 · 计算机科学 2017-10-31 Florian Dubost , Gerda Bortsova , Hieab Adams , Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen De Bruijne

Estimation and inference with modern longitudinal data from wearable devices, which consist of biological signals at high-frequency time points, is burdened by massive computational costs. We propose a distributed estimation and inference…

统计方法学 · 统计学 2023-09-13 Cole Manschot , Emily C. Hector

Automatic lesion analysis is critical in skin cancer diagnosis and ensures effective treatment. The computer aided diagnosis of such skin cancer in dermoscopic images can significantly reduce the clinicians workload and help improve…

图像与视频处理 · 电气工程与系统科学 2023-01-18 Shubham Innani , Prasad Dutande , Bhakti Baheti , Ujjwal Baid , Sanjay Talbar