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Self-supervised learning (SSL) has emerged as a powerful approach for learning visual representations without manual annotations. However, the robustness of standard SSL methods to domain shift -- systematic differences across data sources…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Stella Su , Marc Harary , Scott J. Rodig , William Lotter

Whole Slide Image (WSI) representation is critical for cancer subtyping, cancer recognition and mutation prediction.Training an end-to-end WSI representation model poses significant challenges, as a standard gigapixel slide can contain tens…

计算机视觉与模式识别 · 计算机科学 2025-11-10 Jing Jin , Xu Liu , Te Gao , Zhihong Shi , Yixiong Liang , Ruiqing Zheng , Hulin Kuang , Min Zeng , Shichao Kan

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

计算机视觉与模式识别 · 计算机科学 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

DNA methylation is an epigenetic mechanism that regulates gene expression by adding methyl groups to DNA. Abnormal methylation patterns can disrupt gene expression and have been linked to cancer development. To quantify DNA methylation,…

图像与视频处理 · 电气工程与系统科学 2025-04-09 Manahil Raza , Muhammad Dawood , Talha Qaiser , Nasir M. Rajpoot

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

The emergence of digital pathology has opened new horizons for histopathology and cytology. Artificial-intelligence algorithms are able to operate on digitized slides to assist pathologists with diagnostic tasks. Whereas machine learning…

Diagnostic, prognostic and therapeutic decision-making of cancer in pathology clinics can now be carried out based on analysis of multi-gigapixel tissue images, also known as whole-slide images (WSIs). Recently, deep convolutional neural…

图像与视频处理 · 电气工程与系统科学 2022-09-08 Quoc Dang Vu , Kashif Rajpoot , Shan E Ahmed Raza , Nasir Rajpoot

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

计算机视觉与模式识别 · 计算机科学 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

计算机视觉与模式识别 · 计算机科学 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Automatic medical image segmentation has wide applications for disease diagnosing. However, it is much more challenging than natural optical image segmentation due to the high-resolution of medical images and the corresponding huge…

计算机视觉与模式识别 · 计算机科学 2020-12-18 Ziqiang Li , Rentuo Tao , Qianrun Wu , Bin Li

Digitized pathological diagnosis has been in increasing demand recently. It is well known that color information is critical to the automatic and visual analysis of pathological slides. However, the color variations due to various factors…

图像与视频处理 · 电气工程与系统科学 2024-02-13 Shaojin Cai , Yuyang Xue3 Qinquan Gao , Min Du , Gang Chen , Hejun Zhang , Tong Tong

With promising results of machine learning based models in computer vision, applications on medical imaging data have been increasing exponentially. However, generalizations to complex real-world clinical data is a persistent problem. Deep…

计算机视觉与模式识别 · 计算机科学 2020-07-27 Nooshin Mojab , Vahid Noroozi , Darvin Yi , Manoj Prabhakar Nallabothula , Abdullah Aleem , Phillip S. Yu , Joelle A. Hallak

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

计算机视觉与模式识别 · 计算机科学 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

Domain adaptation, which bridges the distributions across different modalities, plays a crucial role in multimodal medical image analysis. In endoscopic imaging, combining pre-operative data with intra-operative imaging is important for…

图像与视频处理 · 电气工程与系统科学 2025-07-16 Junyang Wu , Fangfang Xie , Jiayuan Sun , Yun Gu , Guang-Zhong Yang

Deep learning has shown great promise in diverse areas of computer vision, such as image classification, object detection and semantic segmentation, among many others. However, as it has been repeatedly demonstrated, deep learning methods…

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is not only time and resource consuming, but also very challenging even for experienced pathologists,…

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). However, existing approaches typically rely on pre-trained models from large natural image datasets, such as…

计算机视觉与模式识别 · 计算机科学 2023-03-24 Yi Lin , Zhongchen Zhao , Zhengjie ZHU , Lisheng Wang , Kwang-Ting Cheng , Hao Chen

Background: The use of whole slide imaging (WSI) for digital pathology has recently been cleared for primary diagnosis in the US. A conventional WSI system scans the tissue slide to different positions and acquires the digital images. In a…

图像与视频处理 · 电气工程与系统科学 2019-07-26 Shaowei Jiang , Zichao Bian , Xizhi Huang , Pengming Song , He Zhang , Yongbing Zhang , Guoan Zheng

Due to the recent advancements in machine vision, digital pathology has gained significant attention. Histopathology images are distinctly rich in visual information. The tissue glass slide images are utilized for disease diagnosis.…

图像与视频处理 · 电气工程与系统科学 2020-11-02 Danial Maleki , Mehdi Afshari , Morteza Babaie , H. R. Tizhoosh