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The literature on Gaussian graphical models (GGMs) contains two equally rich and equally significant domains of research efforts and interests. The first research domain relates to the problem of graph determination. That is, the underlying…

统计方法学 · 统计学 2014-11-25 Adrian Dobra

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

计算机视觉与模式识别 · 计算机科学 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

A soundscape is defined by the acoustic environment a person perceives at a location. In this work, we propose a framework for mapping soundscapes across the Earth. Since soundscapes involve sound distributions that span varying spatial…

Statistical Parametric Mapping (SPM) is an integrated set of methods for testing hypotheses about the brain's structure and function, using data from imaging devices. These methods are implemented in an open source software package, SPM,…

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

统计方法学 · 统计学 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

应用统计 · 统计学 2015-05-27 Peter J. Diggle , Emanuele Giorgi

Spatial data are gaining increasing importance in many areas of research. Particularly spatial health data are becoming increasingly important for medical research, for example, to better understand relationships between environmental…

密码学与安全 · 计算机科学 2025-09-10 Simon Cremer , Lydia Jehmlich , Rainer Lenz

Understanding the complex nature of spatial information is crucial for problem solving in social and environmental sciences. This study investigates how the underlying patterns of spatial data can significantly influence the outcomes of…

物理与社会 · 物理学 2024-09-17 Peng Luo , Yongze Song , Wenwen Li , Liqiu Meng

Stochastic Process Model has many applications in analysis of longitudinal biodemographic data. Such data contain various physiological variables (sometimes known as covariates). It also can potentially contain genetic information available…

种群与进化 · 定量生物学 2016-05-31 Ilya Zhbannikov , Konstantin Arbeev , Anatoliy Yashin

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such…

应用统计 · 统计学 2026-04-22 Pritam Dey , Rajarshi Guhaniyogi , Yang Ni , Bani K. Mallick

Machine learning holds tremendous promise for transforming the fundamental practice of scientific discovery by virtue of its data-driven nature. With the ever-increasing stream of research data collection, it would be appealing to…

机器学习 · 计算机科学 2024-03-06 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai

Spatial transcriptomics measures the expression of thousands of genes in a tissue sample while preserving its spatial structure. This class of technologies has enabled the investigation of the spatial variation of gene expressions and their…

统计方法学 · 统计学 2025-10-23 Andrea Sottosanti , Davide Risso , Francesco Denti

Spatial transcriptomics (ST) enables the visualization of gene expression within the context of tissue morphology. This emerging discipline has the potential to serve as a foundation for developing tools to design precision medicines.…

图像与视频处理 · 电气工程与系统科学 2024-11-12 Shivam Kumar , Samrat Chatterjee

Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

统计方法学 · 统计学 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

Spatial transcriptomics has revolutionized tissue analysis by simultaneously mapping gene expression, spatial topography, and histological context across consecutive tissue sections, enabling systematic investigation of spatial…

应用统计 · 统计学 2025-10-24 Meng Zhou , Shuangge Ma , Mengyun Wu

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

定量方法 · 定量生物学 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

The location, timing, and abundance of gene expression (both mRNA and proteins) within a tissue define the molecular mechanisms of cell functions. Recent technology breakthroughs in spatial molecular profiling, including imaging-based…

应用统计 · 统计学 2020-12-10 Qiwei Li , Minzhe Zhang , Yang Xie , Guanghua Xiao

Statistical shape modeling (SSM) has recently taken advantage of advances in deep learning to alleviate the need for a time-consuming and expert-driven workflow of anatomy segmentation, shape registration, and the optimization of…

计算机视觉与模式识别 · 计算机科学 2020-07-14 Jadie Adams , Riddhish Bhalodia , Shireen Elhabian

Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics,…

图像与视频处理 · 电气工程与系统科学 2022-09-14 Krithika Iyer , Alan Morris , Brian Zenger , Karthik Karanth , Benjamin A Orkild , Oleksandre Korshak , Shireen Elhabian

Statistical shape modeling (SSM) is an enabling quantitative tool to study anatomical shapes in various medical applications. However, directly using 3D images in these applications still has a long way to go. Recent deep learning methods…

计算机视觉与模式识别 · 计算机科学 2023-10-04 Abu Zahid Bin Aziz , Jadie Adams , Shireen Elhabian
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