相关论文: AI Gone Astray: Technical Supplement

With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing…

Sepsis is a life-threatening condition caused by the body's response to an infection. In order to treat patients with sepsis, physicians must control varying dosages of various antibiotics, fluids, and vasopressors based on a large number…

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…

In the emergency department (ED), patients undergo triage and multiple laboratory tests before diagnosis. This time-consuming process causes ED crowding which impacts patient mortality, medical errors, staff burnout, etc. This work proposes…

Clinical Artificial lntelligence (AI) applications are rapidly expanding worldwide, and have the potential to impact to all areas of medical practice. Medical imaging applications constitute a vast majority of approved clinical AI…

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Spiking Neural Networks (SNNs) have recently become more popular as a biologically plausible substitute for traditional Artificial Neural Networks (ANNs). SNNs are cost-efficient and deployment-friendly because they process input in both…

Machine learning has successfully framed many sequential decision making problems as either supervised prediction, or optimal decision-making policy identification via reinforcement learning. In data-constrained offline settings, both…

Sepsis is one of the leading causes of death in Intensive Care Units (ICU). The strategy for treating sepsis involves the infusion of intravenous (IV) fluids and administration of antibiotics. Determining the optimal quantity of IV fluids…

The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this…

The deployment of machine learning in high-stakes services relies on ``human-in-the-loop'' architectures to mitigate algorithmic uncertainty. However, existing static policies fail to address a fundamental tension: algorithms suffer from…

Neural network representation learning frameworks have recently shown to be highly effective at a wide range of tasks ranging from radiography interpretation via data-driven diagnostics to clinical decision support. This often superior…

Clinical trials disruption has always represented a non negligible part of the ending of interventional studies. While the SARS-CoV-2 (COVID-19) pandemic has led to an impressive and unprecedented initiation of clinical research, it has…

Sepsis is a major cause of mortality in the intensive care units (ICUs). Early intervention of sepsis can improve clinical outcomes for sepsis patients. Machine learning models have been developed for clinical recognition of sepsis. A…

We design and implement a temporal convolutional network model to predict sepsis onset. Our model is trained on data extracted from MIMIC III database, based on a retrospective analysis of patients admitted to intensive care unit who did…

Output from generative AI such as ChatGPT, can be repetitive and biased. But more worrying is that this output can mysteriously tip mid-response from good (correct) to bad (misleading or wrong) without the user noticing. In 2024 alone, this…

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…

Real-world clinical time series data sets exhibit a high prevalence of missing values. Hence, there is an increasing interest in missing data imputation. Traditional statistical approaches impose constraints on the data-generating process…

Predicting the risk of mortality for patients with acute myocardial infarction (AMI) using electronic health records (EHRs) data can help identify risky patients who might need more tailored care. In our previous work, we built…