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Many Mendelian randomization (MR) papers have been conducted only in people of European ancestry, limiting transportability of results to the global population. Expanding MR to diverse ancestry groups is essential to ensure equitable…

This paper analyzes the possibilities of using the generalized ridge regression to mitigate multicollinearity in a multiple linear regression model. For this purpose, we obtain the expressions for the estimated variance, the coefficient of…

统计方法学 · 统计学 2025-04-09 Román Salmerón Gómez , Catalina García García , Guillermo Hortal Reina

Modern high-throughput biomedical devices routinely produce data on a large scale, and the analysis of high-dimensional datasets has become commonplace in biomedical studies. However, given thousands or tens of thousands of measured…

统计方法学 · 统计学 2022-02-28 Vladimir Vutov , Thorsten Dickhaus

We develop a new method for multivariate scalar on multidimensional distribution regression. Traditional approaches typically analyze isolated univariate scalar outcomes or consider unidimensional distributional representations as…

统计方法学 · 统计学 2023-10-17 Rahul Ghosal , Marcos Matabuena

The product moment covariance is a cornerstone of multivariate data analysis, from which one can derive correlations, principal components, Mahalanobis distances and many other results. Unfortunately the product moment covariance and the…

统计方法学 · 统计学 2021-05-21 Jakob Raymaekers , Peter J. Rousseeuw

It is of great interest to quantify the contributions of genetic variation to brain structure and function, which are usually measured by high-dimensional imaging data (e.g., magnetic resonance imaging). In addition to the variance, the…

应用统计 · 统计学 2020-05-05 Benjamin B. Risk , Hongtu Zhu

We study correlation measures for complex systems. First, we investigate some recently proposed measures based on information geometry. We show that these measures can increase under local transformations as well as under discarding…

适应与自组织系统 · 物理学 2012-04-20 Tobias Galla , Otfried Gühne

While the problem of testing multivariate normality has received considerable attention in the classical low-dimensional setting where the sample size $n$ is much larger than the feature dimension $d$ of the data, there is presently a…

统计方法学 · 统计学 2025-12-23 Xin Bing , Derek Latremouille

Machine learning tools have empowered a qualitatively new way to perform differential cross section measurements whereby the data are unbinned, possibly in many dimensions. Unbinned measurements can enable, improve, or at least simplify…

Univariate and multivariate normal probability distributions are widely used when modeling decisions under uncertainty. Computing the performance of such models requires integrating these distributions over specific domains, which can vary…

机器学习 · 统计学 2024-07-31 Abhranil Das , Wilson S Geisler

High-dimensional tests are applied to find relevant sets of variables and relevant models. If variables are selected by analyzing the sums of products matrices and a corresponding mean-value test is performed, there is the danger that the…

统计方法学 · 统计学 2012-02-10 Juergen Laeuter , Maciej Rosolowski , Ekkehard Glimm

We propose two tests for the equality of covariance matrices between two high-dimensional populations. One test is on the whole variance--covariance matrices, and the other is on off-diagonal sub-matrices, which define the covariance…

统计理论 · 数学 2012-06-06 Jun Li , Song Xi Chen

Measuring inequalities in a multidimensional framework is a challenging problem which is common to most field of science and engineering. Nevertheless, despite the enormous amount of researches illustrating the fields of application of…

物理与社会 · 物理学 2025-03-19 Giuseppe Toscani

This paper considers the problem of testing temporal homogeneity of $p$-dimensional population mean vectors from the repeated measurements of $n$ subjects over $T$ times. To cope with the challenges brought by high-dimensional longitudinal…

统计方法学 · 统计学 2016-08-29 Ping-Shou Zhong , Jun Li

Diversity is a concept relevant to numerous domains of research varying from ecology, to information theory, and to economics, to cite a few. It is a notion that is steadily gaining attention in the information retrieval, network analysis,…

Introduction: Even in effectively conducted randomised trials, the probability of a successful study remains relatively low. With recent advances in the next-generation sequencing technologies, there is a rapidly growing number of…

In recent years, networks with higher-order interactions have emerged as a powerful tool to model complex systems. Comparing these higher-order systems remains however a challenge. Traditional similarity measures designed for pairwise…

物理与社会 · 物理学 2026-02-24 Cosimo Agostinelli , Marco Mancastroppa , Alain Barrat

It is increasingly common to evaluate the same coreference resolution (CR) model on multiple datasets. Do these multi-dataset evaluations allow us to draw meaningful conclusions about model generalization? Or, do they rather reflect the…

计算与语言 · 计算机科学 2024-06-19 Ian Porada , Alexandra Olteanu , Kaheer Suleman , Adam Trischler , Jackie Chi Kit Cheung

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

In many important statistical analyses, the number of covariates $p$ often exceeds the data size $n$, a regime commonly referred to as high-dimensional. While considerable progress has been made in high-dimensional regression under the…

统计方法学 · 统计学 2026-05-29 Herman Tesso , Georges Nguefack-Tsague