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Biomedical knowledge graphs (KGs) are widely used across research and translational settings, yet their design decisions and implementation are often opaque. Unlike ontologies that more frequently adhere to established creation principles,…

Knowledge graphs (KGs) have emerged as a powerful framework for representing and integrating complex biomedical information. However, assembling KGs from diverse sources remains a significant challenge in several aspects, including entity…

机器学习 · 计算机科学 2023-10-10 Yijia Xiao , Dylan Steinecke , Alexander Russell Pelletier , Yushi Bai , Peipei Ping , Wei Wang

Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and leveraging the vast and complex data found across the biomedical field. Yet, current reviews of BKGs often limit their scope to specific domains or…

计算与语言 · 计算机科学 2025-01-23 Yuxing Lu , Sin Yee Goi , Xukai Zhao , Jinzhuo Wang

Knowledge-based biomedical data science (KBDS) involves the design and implementation of computer systems that act as if they knew about biomedicine. Such systems depend on formally represented knowledge in computer systems, often in the…

人工智能 · 计算机科学 2022-09-13 Tiffany J. Callahan , Harrison Pielke-Lombardo , Ignacio J. Tripodi , Lawrence E. Hunter

Knowledge graphs and ontologies represent entities and their relationships in a structured way, having gained significance in the development of modern AI applications. Integrating these semantic resources with machine learning models often…

机器学习 · 计算机科学 2025-09-10 Hamid Ahmad , Heiko Paulheim , Rita T. Sousa

Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…

人工智能 · 计算机科学 2025-05-26 Xiaochen Wang , Yuan Zhong , Lingwei Zhang , Lisong Dai , Ting Wang , Fenglong Ma

Knowledge graphs (KGs) serve as powerful tools for organizing and representing structured knowledge. While their utility is widely recognized, challenges persist in their automation and completeness. Despite efforts in automation and the…

人工智能 · 计算机科学 2024-05-07 Mutahira Khalid , Raihana Rahman , Asim Abbas , Sushama Kumari , Iram Wajahat , Syed Ahmad Chan Bukhari

Domain experts often rely on most recent knowledge for apprehending and disseminating specific biological processes that help them design strategies for developing prevention and therapeutic decision-making in various disease scenarios. A…

Biomedical knowledge graphs (KGs) are widely used in the life sciences, yet many are derived from unstructured documents and therefore lack schema-level constrains, whereas graphs assembled from structured resources are difficult to…

Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and…

计算与语言 · 计算机科学 2022-04-04 Sihang Zeng , Zheng Yuan , Sheng Yu

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

人工智能 · 计算机科学 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Structured and unstructured data and facts about drugs, genes, protein, viruses, and their mechanism are spread across a huge number of scientific articles. These articles are a large-scale knowledge source and can have a huge impact on…

人工智能 · 计算机科学 2023-02-24 Md. Rezaul Karim , Lina Molinas Comet , Oya Beyan , Dietrich Rebholz-Schuhmann , Stefan Decker

Background : Knowledge is evolving over time, often as a result of new discoveries or changes in the adopted methods of reasoning. Also, new facts or evidence may become available, leading to new understandings of complex phenomena. This is…

计算与语言 · 计算机科学 2023-04-24 Ayoub Harnoune , Maryem Rhanoui , Mounia Mikram , Siham Yousfi , Zineb Elkaimbillah , Bouchra El Asri

Background: More than 400,000 biomedical concepts and some of their relationships are contained in SnomedCT, a comprehensive biomedical ontology. However, their concept names are not always readily interpretable by non-experts, or patients…

计算与语言 · 计算机科学 2023-06-02 François Remy , Thomas Demeester

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Published biomedical information has and continues to rapidly increase. The recent advancements in Natural Language Processing (NLP), have generated considerable interest in automating the extraction, normalization, and representation of…

计算与语言 · 计算机科学 2024-04-24 Armando D. Diaz Gonzalez , Kevin S. Hughes , Songhui Yue , Sean T. Hayes

Background: Recent years are seeing a growing impetus in the semantification of scholarly knowledge at the fine-grained level of scientific entities in knowledge graphs. The Open Research Knowledge Graph (ORKG) https://www.orkg.org/…

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

机器学习 · 计算机科学 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

计算与语言 · 计算机科学 2021-09-22 Rahul Nadkarni , David Wadden , Iz Beltagy , Noah A. Smith , Hannaneh Hajishirzi , Tom Hope
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