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Randomization is a fundamental tool used in many theoretical and practical areas of computer science. We study here the role of randomization in the area of submodular function maximization. In this area most algorithms are randomized, and…

数据结构与算法 · 计算机科学 2015-08-11 Niv Buchbinder , Moran Feldman

AI systems are often used to make or contribute to important decisions in a growing range of applications, including criminal justice, hiring, and medicine. Since these decisions impact human lives, it is important that the AI systems act…

There is a fast-growing literature on estimating optimal treatment rules directly by maximizing the expected outcome. In biomedical studies and operations applications, censored survival outcome is frequently observed, in which case the…

统计方法学 · 统计学 2026-03-12 Yifan Cui , Junyi Liu , Tao Shen , Zhengling Qi , Xi Chen

Workers spend a significant amount of time learning how to make good decisions. Evaluating the efficacy of a given decision, however, can be complicated -- e.g., decision outcomes are often long-term and relate to the original decision in…

机器学习 · 计算机科学 2024-03-20 Hamsa Bastani , Osbert Bastani , Wichinpong Park Sinchaisri

Variable selection for optimal treatment regime in a clinical trial or an observational study is getting more attention. Most existing variable selection techniques focused on selecting variables that are important for prediction, therefore…

统计方法学 · 统计学 2014-05-22 Ailin Fan , Wenbin Lu , Rui Song

We develop and evaluate tolerance interval methods for dynamic treatment regimes (DTRs) that can provide more detailed prognostic information to patients who will follow an estimated optimal regime. Although the problem of constructing…

统计方法学 · 统计学 2017-04-26 Daniel J. Lizotte , Arezoo Tahmasebi

An endeavor central to precision medicine is predictive biomarker discovery; they define patient subpopulations which stand to benefit most, or least, from a given treatment. The identification of these biomarkers is often the byproduct of…

统计方法学 · 统计学 2022-08-01 Philippe Boileau , Nina Ting Qi , Mark J. van der Laan , Sandrine Dudoit , Ning Leng

AI agents designed to collaborate with people benefit from models that enable them to anticipate human behavior. However, realistic models tend to require vast amounts of human data, which is often hard to collect. A good prior or…

机器学习 · 计算机科学 2022-11-22 Mesut Yang , Micah Carroll , Anca Dragan

In this overview article we will consider the deliberate restarting of algorithms, a meta technique, in order to improve the algorithm's performance, e.g., convergence rates or approximation guarantees. One of the major advantages is that…

最优化与控制 · 数学 2020-06-29 Sebastian Pokutta

We consider the effects of parameter uncertainty on the optimal radiation schedule in the context of the linear-quadratic model. Our interest arises from the observation that if inter-patient variations in OAR and tumor sensitivities to…

组织与器官 · 定量生物学 2015-06-05 Hamidreza Badri , Yoichi Watanabe , Kevin Leder

Recently, interest has grown in the use of proxy variables of unobserved confounding for inferring the causal effect in the presence of unmeasured confounders from observational data. One difficulty inhibiting the practical use is finding…

机器学习 · 计算机科学 2024-05-28 Feng Xie , Zhengming Chen , Shanshan Luo , Wang Miao , Ruichu Cai , Zhi Geng

An increasing number of decisions regarding the daily lives of human beings are being controlled by artificial intelligence (AI) algorithms in spheres ranging from healthcare, transportation, and education to college admissions,…

计算机与社会 · 计算机科学 2020-01-28 Dana Pessach , Erez Shmueli

In this article, we propose a new algorithm for supervised learning methods, by which one can both capture the non-linearity in data and also find the best subset model. To produce an enhanced subset of the original variables, an ideal…

应用统计 · 统计学 2017-01-23 Peyman Tavallali , Marianne Razavi , Sean Brady

Precision medicine involves developing individualized treatment regimes (ITRs) which allow for treatment decisions to be tailored to patient characteristics. Naturally, the identification of the optimal regime, that is, the rule which…

统计方法学 · 统计学 2025-09-30 Misha Dolmatov , Erica E. M. Moodie , David A. Stephens , Dipankar Bandyopadhyay

The advent of big data has vast potential for discovery in natural phenomena ranging from climate science to medicine, but overwhelming complexity stymies insight. Existing theory is often not able to succinctly describe salient phenomena,…

机器学习 · 计算机科学 2021-06-25 Bryan E. Kaiser , Juan A. Saenz , Maike Sonnewald , Daniel Livescu

Optimal stopping is the problem of determining when to stop a stochastic system in order to maximize reward, which is of practical importance in domains such as finance, operations management and healthcare. Existing methods for…

最优化与控制 · 数学 2022-03-28 Xinyi Guan , Velibor V. Mišić

We consider the task of evaluating policies of algorithmic resource allocation through randomized controlled trials (RCTs). Such policies are tasked with optimizing the utilization of limited intervention resources, with the goal of…

人工智能 · 计算机科学 2023-02-07 Aditya Mate , Bryan Wilder , Aparna Taneja , Milind Tambe

We formalize Prescriptive Artificial Intelligence as a distinct paradigm for human-AI decision collaboration in high-stakes environments. Unlike predictive systems optimized for outcome accuracy, prescriptive systems are designed to…

人工智能 · 计算机科学 2026-03-26 Pedro Passos , Patrick Moratori

Radiation Therapy (RT) plays a pivotal role in the treatment of cancer, offering the potential to effectively target and eliminate tumour cells while minimizing harm to surrounding healthy tissues. However, the success of RT heavily depends…

医学物理 · 物理学 2024-02-16 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Existing approaches to reward inference from behavior typically assume that humans provide demonstrations according to specific models of behavior. However, humans often indicate their goals through a wide range of behaviors, from actions…

机器学习 · 计算机科学 2025-02-26 Will Schwarzer , Jordan Schneider , Philip S. Thomas , Scott Niekum
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