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In computational digital pathology, accurate nuclear segmentation of Hematoxylin and Eosin (H&E) stained whole slide images (WSIs) is a critical step for many analyses and tissue characterizations. One popular deep learning-based nuclear…

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

计算机视觉与模式识别 · 计算机科学 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Accurate image segmentation plays a crucial role in medical image analysis, yet it faces great challenges of various shapes, diverse sizes, and blurry boundaries. To address these difficulties, square kernel-based encoder-decoder…

图像与视频处理 · 电气工程与系统科学 2022-01-02 Qian Yu , Lei Qi , Luping Zhou , Lei Wang , Yilong Yin , Yinghuan Shi , Wuzhang Wang , Yang Gao

The segmentation of cell nuclei in tissue images stained with the blood dye hematoxylin and eosin (H$\&$E) is essential for various clinical applications and analyses. Due to the complex characteristics of cellular morphology, a large…

图像与视频处理 · 电气工程与系统科学 2024-07-26 Ziwei Cui , Jingfeng Yao , Lunbin Zeng , Juan Yang , Wenyu Liu , Xinggang Wang

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

图像与视频处理 · 电气工程与系统科学 2025-06-10 Suman Mahapatra , Pradipta Maji

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

图像与视频处理 · 电气工程与系统科学 2022-02-25 Satoshi Kondo , Satoshi Kasai

Convolutional neural networks (CNNs) achieved the state-of-the-art performance in medical image segmentation due to their ability to extract highly complex feature representations. However, it is argued in recent studies that traditional…

计算机视觉与模式识别 · 计算机科学 2025-03-31 Zhendi Gong , Andrew P. French , Guoping Qiu , Xin Chen

Accurate skin-lesion segmentation remains a key technical challenge for computer-aided diagnosis of skin cancer. Convolutional neural networks, while effective, are constrained by limited receptive fields and thus struggle to model…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Pengyang Yu , Haoquan Wang , Gerard Marks , Tahar Kechadi , Laurence T. Yang , Sahraoui Dhelim , Nyothiri Aung

Nuclear segmentation is important and frequently demanded for pathology image analysis, yet is also challenging due to nuclear crowdedness and possible occlusion. In this paper, we present a novel bottom-up method for nuclear segmentation.…

计算机视觉与模式识别 · 计算机科学 2019-07-11 Jiahui Li , Zhiqiang Hu , Shuang Yang

Nuclei Identification and Counting is the most important morphological feature of cancers, especially in the colon. Many deep learning-based methods have been proposed to deal with this problem. In this work, we construct an extension of…

图像与视频处理 · 电气工程与系统科学 2022-03-07 Vi Thi-Tuong Vo , Soo-Hyung Kim , Taebum Lee

The extraction of consistent and identifiable features from an image of the human iris is known as iris recognition. Identifying which pixels belong to the iris, known as segmentation, is the first stage of iris recognition. Errors in…

计算机视觉与模式识别 · 计算机科学 2018-12-21 Sohaib Ahmad , Benjamin Fuller

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

图像与视频处理 · 电气工程与系统科学 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Nucleus image segmentation is a crucial step in the analysis, pathological diagnosis, and classification, which heavily relies on the quality of nucleus segmentation. However, the complexity of issues such as variations in nucleus size,…

图像与视频处理 · 电气工程与系统科学 2023-08-11 Junzhou Chen , Qian Huang , Yulin Chen , Linyi Qian , Chengyuan Yu

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

计算机视觉与模式识别 · 计算机科学 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

图像与视频处理 · 电气工程与系统科学 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using…

Medical image segmentation is the technique that helps doctor view and has a precise diagnosis, particularly in Colorectal Cancer. Specifically, with the increase in cases, the diagnosis and identification need to be faster and more…

图像与视频处理 · 电气工程与系统科学 2023-06-16 Trong-Hieu Nguyen Mau , Quoc-Huy Trinh , Nhat-Tan Bui , Minh-Triet Tran , Hai-Dang Nguyen

Nuclear segmentation is an important step for profiling aberrant regions of histology sections. However, segmentation is a complex problem as a result of variations in nuclear geometry (e.g., size, shape), nuclear type (e.g., epithelial,…

计算机视觉与模式识别 · 计算机科学 2018-02-16 Mina Khoshdeli , Bahram Parvin

Medical image segmentation plays an essential role in developing computer-assisted diagnosis and therapy systems, yet still faces many challenges. In the past few years, the popular encoder-decoder architectures based on CNNs (e.g., U-Net)…

计算机视觉与模式识别 · 计算机科学 2021-07-20 Guoping Xu , Xingrong Wu , Xuan Zhang , Xinwei He

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

图像与视频处理 · 电气工程与系统科学 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir