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Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains.…

机器学习 · 计算机科学 2026-05-27 Nikita Dhawan , Arnav Paruthi , Andrew Kim , Lovedeep Gondara , Jekaterina Novikova , Chris J. Maddison

Selective Classification, wherein models can reject low-confidence predictions, promises reliable translation of machine-learning based classification systems to real-world scenarios such as clinical diagnostics. While current evaluation of…

The increasing adoption of neural networks in learning-augmented systems highlights the importance of model safety and robustness, particularly in safety-critical domains. Despite progress in the formal verification of neural networks,…

机器学习 · 计算机科学 2024-10-25 Shuowei Jin , Francis Y. Yan , Cheng Tan , Anuj Kalia , Xenofon Foukas , Z. Morley Mao

The FDA's Project Optimus initiative emphasizes patient-centered dose selection in oncology that balances efficacy and safety. We develop a framework for randomized dose optimization studies that uses clinically interpretable utility scores…

应用统计 · 统计学 2026-03-24 Xuemin Gu , Cong Xu , Lei Xu , Ying Yu

In this paper we build a joint model which can accommodate for binary, ordinal and continuous responses, by assuming that the errors of the continuous variables and the errors underlying the ordinal and binary outcomes follow a multivariate…

统计方法学 · 统计学 2024-11-06 Laura Vana-Gür , Rainer Hirk

Temporal relational data, perhaps the most commonly used data type in industrial machine learning applications, needs labor-intensive feature engineering and data analyzing for giving precise model predictions. An automatic machine learning…

机器学习 · 计算机科学 2021-09-10 Zhipeng Luo , Zhixing He , Jin Wang , Manqing Dong , Jianqiang Huang , Mingjian Chen , Bohang Zheng

Conformal prediction provides a powerful framework for constructing distribution-free prediction regions with finite-sample coverage guarantees. While extensively studied in univariate settings, its extension to multi-output problems…

机器学习 · 统计学 2025-02-04 Victor Dheur , Matteo Fontana , Yorick Estievenart , Naomi Desobry , Souhaib Ben Taieb

We introduce a performance-driven framework for constructing strictly causal forward-oriented observables in strongly non-stationary time series. The method combines a robustly normalized composite of heterogeneous indicators with a…

计算金融 · 定量金融 2026-03-17 Lucas A. Souza

Cluster-randomized trials (CRTs) are widely used to evaluate group-level interventions and increasingly collect multiple outcomes capturing complementary dimensions of benefit and risk. Investigators often seek a single global summary of…

统计方法学 · 统计学 2026-01-22 Xinyuan Chen , Fan Li

Many outcomes of interest in the social and health sciences, as well as in modern applications in computational social science and experimentation on social media platforms, are ordinal and do not have a meaningful scale. Causal analyses…

统计方法学 · 统计学 2015-01-07 Alexander Volfovsky , Edoardo M. Airoldi , Donald B. Rubin

Machine learning is increasingly being used to generate prediction models for use in a number of real-world settings, from credit risk assessment to clinical decision support. Recent discussions have highlighted potential problems in the…

With an increasing focus on precision medicine in medical research, numerous studies have been conducted in recent years to clarify the relationship between treatment effects and patient characteristics. The treatment effects for patients…

统计方法学 · 统计学 2023-09-22 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

In regression models, predictor variables with inherent ordering, such as tumor staging ranging and ECOG performance status, are commonly seen in medical settings. Statistically, it may be difficult to determine the functional form of an…

统计方法学 · 统计学 2020-08-04 Emily Roberts , Lili Zhao

Scoring systems, as a type of predictive model, have significant advantages in interpretability and transparency and facilitate quick decision-making. As such, scoring systems have been extensively used in a wide variety of industries such…

机器学习 · 计算机科学 2022-11-23 Yi Yang , Ying Wu , Mei Li , Xiangyu Chang , Yong Tan

The use of tiered warnings and multicategorical forecasts are ubiquitous in meteorological operations. Here, a flexible family of scoring functions is presented for evaluating the performance of ordered multicategorical forecasts. Each…

应用统计 · 统计学 2022-05-02 Robert Taggart , Nicholas Loveday , Deryn Griffiths

Multi-modal generative document parsing systems challenge traditional evaluation: unlike deterministic OCR or layout models, they often produce semantically correct yet structurally divergent outputs. Conventional metrics-CER, WER, IoU, or…

计算与语言 · 计算机科学 2025-09-25 Renyu Li , Antonio Jimeno Yepes , Yao You , Kamil Pluciński , Maximilian Operlejn , Crag Wolfe

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

定量方法 · 定量生物学 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Causal inference analysis is the estimation of the effects of actions on outcomes. In the context of healthcare data this means estimating the outcome of counter-factual treatments (i.e. including treatments that were not observed) on a…

统计方法学 · 统计学 2018-03-21 Yishai Shimoni , Chen Yanover , Ehud Karavani , Yaara Goldschmnidt

AI-driven automated scoring systems offer scalable and efficient means of evaluating complex student-generated responses. Yet, despite increasing demand for transparency and interpretability, the field has yet to develop a widely accepted…

计算与语言 · 计算机科学 2026-04-23 Yunsung Kim , Mike Hardy , Joseph Tey , Candace Thille , Chris Piech

Randomized trials typically estimate average relative treatment effects, but decisions on the benefit of a treatment are possibly better informed by more individualized predictions of the absolute treatment effect. In case of a binary…

统计方法学 · 统计学 2021-08-20 J Hoogland , J IntHout , M Belias , MM Rovers , RD Riley , FE Harrell , KGM Moons , TPA Debray , JB Reitsma