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Decoding stimuli or behaviour from recorded neural activity is a common approach to interrogate brain function in research, and an essential part of brain-computer and brain-machine interfaces. Reliable decoding even from small neural…

神经元与认知 · 定量生物学 2023-01-06 Justin Jude , Matthew G. Perich , Lee E. Miller , Matthias H. Hennig

A powerful approach for understanding neural population dynamics is to extract low-dimensional trajectories from population recordings using dimensionality reduction methods. Current approaches for dimensionality reduction on neural data…

机器学习 · 统计学 2017-11-07 Marcel Nonnenmacher , Srinivas C. Turaga , Jakob H. Macke

Randomly connected neural networks have long served as a theoretical tool for studying collective dynamics in neural populations, yet quantitative comparisons to experiments remain limited. Recent technological advances have made it…

神经元与认知 · 定量生物学 2026-05-27 Zehui Zhao , Michael J Pasek , Ilya M Nemenman

Neural population activity often exhibits regime-dependent non-stationarity in the form of switching dynamics. Learning accurate switching dynamical system models can reveal how behavior is encoded in neural activity. Existing switching…

机器学习 · 计算机科学 2025-12-16 DongKyu Kim , Han-Lin Hsieh , Maryam M. Shanechi

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

神经元与认知 · 定量生物学 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

Learning shared structure across environments facilitates rapid learning and adaptive behavior in neural systems. This has been widely demonstrated and applied in machine learning to train models that are capable of generalizing to novel…

机器学习 · 统计学 2025-04-09 Ayesha Vermani , Josue Nassar , Hyungju Jeon , Matthew Dowling , Il Memming Park

Increasingly, human behavior is captured on mobile devices, leading to an increased interest in automated human activity recognition. However, existing datasets typically consist of scripted movements. Our long-term goal is to perform…

机器学习 · 计算机科学 2022-07-12 Garrett Wilson , Janardhan Rao Doppa , Diane J. Cook

Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…

There exist very few ways to isolate cognitive processes, historically defined via highly controlled laboratory studies, in more ecologically valid contexts. Specifically, it remains unclear as to what extent patterns of neural activity…

神经元与认知 · 定量生物学 2023-10-13 Stephen M. Gordon , Jonathan R. McDaniel , Kevin W. King , Vernon J. Lawhern , Jonathan Touryan

Latent dynamics models have emerged as powerful tools for modeling and interpreting neural population activity. Recently, there has been a focus on incorporating simultaneously measured behaviour into these models to further disentangle…

神经元与认知 · 定量生物学 2021-10-29 Cole Hurwitz , Akash Srivastava , Kai Xu , Justin Jude , Matthew G. Perich , Lee E. Miller , Matthias H. Hennig

Recent whole brain imaging experiments on $\textit{C. elegans}$ has revealed that the neural population dynamics encode motor commands and stereotyped transitions between behaviors on low dimensional manifolds. Efforts to characterize the…

定量方法 · 定量生物学 2020-04-15 Charles Fieseler , Manuel Zimmer , J. Nathan Kutz

Brain-wide recordings of large-scale networks of neurons now provide an unprecedented view into how the brain drives behavior. However, brain activity contains both information directly related to behavior as well as the potential for many…

神经元与认知 · 定量生物学 2026-05-06 Eva Yezerets , En Yang , Misha B. Ahrens , Adam S. Charles

Predicting human motion in unstructured and dynamic environments is difficult as humans naturally exhibit complex behaviors that can change drastically from one environment to the next. In order to alleviate this issue, we propose to encode…

机器人学 · 计算机科学 2019-07-01 Philipp Kratzer , Marc Toussaint , Jim Mainprice

A novel approach for unsupervised domain adaptation for neural networks is proposed. It relies on metric-based regularization of the learning process. The metric-based regularization aims at domain-invariant latent feature representations…

In the context of supervised statistical learning, it is typically assumed that the training set comes from the same distribution that draws the test samples. When this is not the case, the behavior of the learned model is unpredictable and…

机器学习 · 计算机科学 2022-05-12 Antonio-Javier Gallego , Jorge Calvo-Zaragoza , Robert B. Fisher

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

机器学习 · 统计学 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

The neural activity in the visual processing is influenced by both external stimuli and internal brain states. Ideally, a neural predictive model should account for both of them. Currently, there are no dynamic encoding models that…

神经元与认知 · 定量生物学 2025-11-18 Finn Schmidt , Polina Turishcheva , Suhas Shrinivasan , Fabian H. Sinz

Brain-Machine Interfaces (BMIs) have recently emerged as a clinically viable option to restore voluntary movements after paralysis. These devices are based on the ability to extract information about movement intent from neural signals…

机器学习 · 计算机科学 2019-01-16 Ali Farshchian , Juan A. Gallego , Joseph P. Cohen , Yoshua Bengio , Lee E. Miller , Sara A. Solla

We introduce a new representation learning algorithm suited to the context of domain adaptation, in which data at training and test time come from similar but different distributions. Our algorithm is directly inspired by theory on domain…

机器学习 · 统计学 2015-02-10 Hana Ajakan , Pascal Germain , Hugo Larochelle , François Laviolette , Mario Marchand

Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is…

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