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Non-pharmaceutical interventions (NPIs) are effective measures to contain a pandemic. Yet, such control measures commonly have a negative effect on the economy. Here, we propose a macro-level approach to support resolving this…

神经与进化计算 · 计算机科学 2021-02-25 Rohit Salgotra , Thomas Seidelmann , Dominik Fischer , Sanaz Mostaghim , Amiram Moshaiov

This work constructs, analyzes, and simulates a new compartmental SEIR-type model for the dynamics and potential control of the current COVID-19 pandemic. The novelty in this work is two-fold. First, the population is divided according to…

种群与进化 · 定量生物学 2021-05-14 Aycil Cesmelioglu , Kenneth L. Kuttler , Meir Shillor , Anna M. Spagnuolo

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

种群与进化 · 定量生物学 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

In this study we present a dynamical agent-based model to investigate the interplay between the socio-economy of and SEIRS-type epidemic spreading over a geographical area, divided to smaller area districts and further to smallest area…

物理与社会 · 物理学 2022-07-20 Jan E. Snellman , Rafael A. Barrio , Kimmo K. Kaski , Maarit J. Käpylä

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

种群与进化 · 定量生物学 2020-06-09 Evangelos Magirou

We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

种群与进化 · 定量生物学 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

种群与进化 · 定量生物学 2020-04-15 Günter Bärwolff

The outbreak of COVID-19 has highlighted the intricate interplay between public health and economic stability on a global scale. This study proposes a novel reinforcement learning framework designed to optimize health and economic outcomes…

机器学习 · 计算机科学 2024-05-01 Maeghal Jain , Ziya Uddin , Wubshet Ibrahim

Understanding how to effectively control an epidemic spreading on a network is a problem of paramount importance for the scientific community. The ongoing COVID-19 pandemic has highlighted the need for policies that mitigate the spread,…

种群与进化 · 定量生物学 2021-09-14 Carlo Cenedese , Lorenzo Zino , Michele Cucuzzella , Ming Cao

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Covid-19 is one of the most dreaded pandemics/epidemics in the world threatening the human population. The dynamics of this pandemic is quite complicated and prediction of pandemic states often fails. In this work, we study and correlate…

种群与进化 · 定量生物学 2021-10-06 Jyoti Bhadana , R. K. Brojen Singh

We formulate an optimal control problem to determine the lockdown policy to curb an epidemic where other control measures are not available yet. We present a unified framework to model the epidemic and economy that allows us to study the…

系统与控制 · 电气工程与系统科学 2022-01-20 Jagtap Kalyani Devendra , Kundan Kandhway

Motivated by epidemics such as COVID-19, we study the spread of a contagious disease when behavior responds to the disease's prevalence. We extend the SIR epidemiological model to include endogenous meeting rates. Individuals benefit from…

种群与进化 · 定量生物学 2023-09-25 Krishna Dasaratha

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

种群与进化 · 定量生物学 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

Different countries -- and sometimes different regions within the same countries -- have adopted different strategies in trying to contain the ongoing COVID-19 epidemic; these mix in variable parts social confinement, early detection and…

种群与进化 · 定量生物学 2020-07-17 Giuseppe Gaeta

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

物理与社会 · 物理学 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

The mathematical interpretation of interventions for the mitigation of epidemics and pandemics in the literature often involves finding the optimal time to initiate an intervention and/or the use of infections to manage impact. Whilst these…

种群与进化 · 定量生物学 2023-05-17 James Van Yperen , Eduard Campillo-Funollet , Rebecca Inkpen , Anjum Memon , Anotida Madzvamuse

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

种群与进化 · 定量生物学 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

We consider here an extended SIR model, including several features of the recent COVID-19 outbreak: in particular the infected and recovered individuals can either be detected (+) or undetected (-) and we also integrate an intensive care…

种群与进化 · 定量生物学 2020-05-25 Arthur Charpentier , Romuald Elie , Mathieu Laurière , Viet Chi Tran

The COVID-19 pandemic highlighted significant challenges in the allocation of vital healthcare resources. Existing epidemiological models, specifically compartmental models, aimed to predict the spread of the COVID-19 virus and its impact…

物理与社会 · 物理学 2024-03-14 Hieu Bui , Sandra Eksioglu , Ruben Proano