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There has been a recent tremendous interest in label-free detection of biomarkers which is a critical enabler of point-of-need diagnostics. A low-power, small form factor, multiplexed wearable system is proposed for continuous detection of…

信号处理 · 电气工程与系统科学 2021-04-06 Devangsingh Sankhala , Madhavi Pali , Kai-Chun Lin , Badrinath Jagannath , Sriram Muthukumar , Shalini Prasad

Microwave sensors are very promising for sensing the blood glucose levels non-invasively for their non-ionizing nature, miniaturized sizing, and low health risks for diabetics. All these features offer the possibility for realizing a…

A high-Q sensor integrating microstrip line (MLIN) main field and split ring resonators is presented for non-invasive glucose sensing. The proposed sensor combines the field-focusing effects of split ring resonators with the enhanced field…

医学物理 · 物理学 2025-03-04 Brandon Kaiheng Tay , Saumitra Kapoor , Wenwei Yu , Shao Ying Huang

Accurately detecting hypoglycemia without invasive glucose sensors remains a critical challenge in diabetes management, particularly in regions where continuous glucose monitoring (CGM) is prohibitively expensive or clinically inaccessible.…

人机交互 · 计算机科学 2026-02-12 Lawrence Obiuwevwi , Krzysztof J. Rechowicz , Vikas Ashok , Sampath Jayarathna

We propose a new label-free ultrasonic sensor, which comprises a slot wave-guide and double silicon-on-insulator (SOI) slot micro-ring resonators. The all-optical sensors do not suffer from electromagnetic interference. We choose to…

光学 · 物理学 2022-04-04 Cheng Mei Zhang , Chao Ying Zhao

Continuous glucose monitoring (CGM) is vital for diabetes care, but current systems rely on invasive implants or electrochemical sensors that often cause discomfort and skin irritation. Non-invasive alternatives remain limited by low…

Biosensing based on whispering-gallery mode (WGM) resonators has been continuously studied with great attention due to its excellent sensitivity guaranteeing the label-free detection. However, its practical impact is insignificant to date…

应用物理 · 物理学 2020-01-08 Yeseul Kim , Hansuek Lee

The measurement of the biological tissue's electrical impedance is an active research field that has attracted a lot of attention during the last decades. Bio-impedances are closely related to a large variety of physiological conditions;…

新兴技术 · 计算机科学 2015-07-14 Saul Rodriguez , Stig Ollmar , Muhammad Waqar , Ana Rusu

In this study, an integrated low-cost and complexity mm-wave structure of Whispering Gallery Mode (WGM) is proposed for sensing the glucose levels in mimicking aquatic solutions of concentrations similar to type 2 diabetics. The bio-sensor…

应用物理 · 物理学 2019-09-30 Ala Eldin Omer , George Shaker , Safieddin Safavi-Naeini

Cell-based biosensors constitute a fundamental tool in biotechnology, and their relevance has greatly increased in recent years as a result of a surging demand for reduced animal testing and for high-throughput and cost-effective in vitro…

A low-power wearable wireless sensor measuring both molecular biomarkers and physiological signals is proposed, where the former are measured by a microfluidic biosensing system while the latter are measured electrically. The low-power…

信号处理 · 电气工程与系统科学 2019-07-04 Xueyuan Zhao , Vidyasagar Sadhu , Tuan Le , Dario Pompili , Mehdi Javanmard

Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

医学物理 · 物理学 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

Studies of biological solutions require high measurement accuracy, the ability to detect low changes in substance concentration, and small amounts of the liquid under test. A microwave complex permittivity measurement technique based on a…

Passive wireless sensors are crucial in modern medical and industrial settings to monitor procedures and conditions. We demonstrate a circuit to inductively excite passive resonators and to conduct their decaying signal response to a low…

信号处理 · 电气工程与系统科学 2025-02-06 Fabian Mohn , Florian Thieben , Tobias Knopp

Label-free biosensors, including conventional quartz-crystal-microbalance (QCM) biosensor, are seriously affected by nonspecific adsorption of contaminants involved in analyte solution, and it is exceptionally difficult to extract the…

生物物理 · 物理学 2021-12-15 Kentaro Noi , Arihiro Iwata , Fumihito Kato , Hirotsugu Ogi

In the case of diabetes, fingertip pricking for a blood sample is inconvenient for glucose measurement. Invasive approaches like laboratory test and one-touch glucometer enhance the risk of blood-related infections. To mitigate this…

信号处理 · 电气工程与系统科学 2021-06-28 Prateek Jain , Amit M. Joshi , Saraju P. Mohanty

Effective diabetes management relies heavily on the continuous monitoring of blood glucose levels, traditionally achieved through invasive and uncomfortable methods. While various non-invasive techniques have been explored, such as optical,…

机器学习 · 计算机科学 2024-08-16 Nihat Ahmadli , Mehmet Ali Sarsil , Onur Ergen

This paper presents a proof-of-concept ultra-low voltage and ultra-low power chronoamperometric electrochemical sensor for non-enzymatic glucose readout integrated circuit (IC) in 130nm CMOS detection featuring a reconfigurable…

Purpose: To develop and evaluate a wearable wireless resonator glasses design that enhances eye MRI signal-to-noise ratio (SNR) without compromising whole-brain image quality at 7 T. Methods: The device integrates two detunable LC loop…

图像与视频处理 · 电气工程与系统科学 2025-09-11 Ming Lu , Xiaoyue Yang , Jason Moore , Pingping Li , Adam W. Anderson , John C. Gore , Seth A. Smith , Xinqiang Yan

Monitoring physiological and behavioral parameters of laboratory rodents is fundamental for biomedical research, yet conventional techniques often rely on invasive sensors or frequent handling that can induce stress and compromise data…

信号处理 · 电气工程与系统科学 2025-12-08 Tommaso Polonelli , Manuel Glahn , Stefano Kron , Stefan Selbert , Marco Garzola , Michele Magno
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