相关论文: Optimizing Vaccine Allocation Strategies in Pandem…

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

As observed during the COVID-19 pandemic, high-income countries, such as the U.S., may exhibit vaccine nationalism during a pandemic: stockpiling doses of vaccine for their own citizens and being reluctant to distribute doses of the vaccine…

How to strategically allocate the available vaccines is a crucial issue for pandemic control. In this work, we propose a mathematical framework for optimal stabilizing vaccine allocation, where our goal is to send the infections to zero as…

Non-pharmacological interventions (NPIs), and in particular social distancing, in conjunction with the advent of effective vaccines at the end of 2020, aspired for the development of a protective immunity shield against the spread of…

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

Massive vaccination against pandemics such as Coronavirus SARS-CoV-2 presents several complexities. The criteria to assess public health policies are fundamental to distribute vaccines in an effective way in order to avoid as many…

The outbreak of a novel coronavirus causing severe acute respiratory syndrome in December 2019 has escalated into a worldwide pandemic. In this work, we propose a compartmental model to describe the dynamics of transmission of infection and…

We evaluate the efficiency of various heuristic strategies for allocating vaccines against COVID-19 and compare them to strategies found using optimal control theory. Our approach is based on a mathematical model which tracks the spread of…

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

To mitigate the pandemic stemming from COVID-19, numerous nations have initiated extensive vaccination campaigns for their citizens since late 2020. While affluent countries have predominantly received vaccine allocations, fewer doses have…

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…

Vaccination campaigns have saved thousands of lives, reaching the farthest places in the world. These campaigns have required substantial investments and accurate coordination between several actors within the vaccine supply chain. Despite…

Early on during a pandemic, vaccine availability is limited, requiring prioritisation of different population groups. Evaluating vaccine allocation is therefore a crucial element of pandemics response. In the present work, we develop a…

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Purpose: Only few companies were able to produce vaccine again COVID-19. Thus, one producer supplied it to many countries. The distribution was not effective. Some countries overstocked the vaccine while other countries were not able to buy…