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Configuring clinical linear accelerators (linacs) for ultra-high dose rate (UHDR) electron experiments typically requires invasive hardware manipulation and/or irreversible manufacturer modifications, limiting broader implementation. We…

Failure modes and effects analysis (FMEA) is one of the most practical design tools implemented in the product design to analyze the possible failures and to improve the design. The use of FMEA is diversified, and different approaches are…

软件工程 · 计算机科学 2021-01-15 Hengameh Fakhravar

Software failures can have catastrophic and costly consequences. Functional Failure Mode and Effects Analysis (FMEA) is a standard technique used within Cyber-Physical Systems (CPS) to identify software failures and assess their…

软件工程 · 计算机科学 2026-04-20 Andrea Bombarda , Federico Conti , Marcello Minervini , Aurora Zanenga , Claudio Menghi

Background & Purpose: FLASH or ultra-high dose rate (UHDR) radiation therapy (RT) has gained attention in recent years for its ability to spare normal tissues relative to conventional dose rate (CDR) RT in various preclinical trials.…

Failure mode and effects analysis (FMEA) is a systematic approach to identify and analyse potential failures and their effects in a system or process. The FMEA approach, however, requires domain experts to manually analyse the FMEA model to…

Reliability Assessment is an indispensable technology for identifying, interpreting, and lessening the potential failures in safety-critical systems like smart grids. Failure modes and effects analysis (FMEA) is one of the well documented…

系统与控制 · 电气工程与系统科学 2022-05-11 Shravan Kumar Akula , Hossein Salehfar , Shayan Behzadirafi

Objectives: Large language models (LLMs) are increasingly used for clinical text summarization, yet structured methods to assess associated patient safety risks remain limited. Failure Mode, Effects, and Criticality Analysis (FMECA)…

Industrial radiography has its inimitable role in non-destructive examinations. Industrial radiography devices, consisting of significantly high activity of the radioisotopes, are operated manually by remotely held control unit.…

仪器与探测器 · 物理学 2016-10-06 Alok Pandey , Meghraj Singh , A. U. Sonawane , Prashant S. Rawat

The automotive industry faces increasing challenges in ensuring both functional safety (FuSa) and cybersecurity for complex semiconductor devices. Traditional Failure Mode and Effects Analysis (FMEA) primarily addresses safety-related…

密码学与安全 · 计算机科学 2026-03-09 Antonino Armato , Marzana Khatun , Sebastian Fischer

Modern microgrids are networked systems comprising physical and cyber components for networking, computation, and monitoring. These cyber components make microgrids more reliable but increase the system complexity. Therefore, risk…

系统与控制 · 电气工程与系统科学 2022-01-04 Shravan Kumar Akula , Hossein Salehfar

Commercial treatment planning systems for electron FLASH radiotherapy are unavailable, and the dosimetric precision required for ultra-high dose rate delivery makes Monte Carlo (MC) simulation the gold standard approach. This work…

Background: FLASH radiotherapy is a treatment regime that delivers therapeutic dose to tumors at an ultra-high dose rate while maintaining adequate normal tissue sparing. However, a comprehensive understanding of the underlying mechanisms,…

Objective: While FLASH radiotherapy is recognized for short-term normal tissue sparing, its durability in late-responding organs remains uncertain, limiting clinical adoption. With its clinical importance and steep dose-response, the spinal…

As systems become increasingly complex, conducting effective safety analysis in the earlier phases of a system's lifecycle is essential to identify and mitigate risks before they escalate. To that end, this paper investigates the…

软件工程 · 计算机科学 2025-11-06 Jannatul Shefa , Taylan G. Topcu

Research on ultra-high dose rate (UHDR) radiation therapy has indicated its potential to spare normal tissue while maintaining equivalent tumor control compared to conventional treatments. First clinical trials are underway. The randomized…

We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiology experiments. UHDR electron beams were controlled by a…

Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…

Purpose: In this study, procedures were developed to achieve efficient reversible conversion of a clinical linear accelerator (LINAC) and deliver electron FLASH (eFLASH) or conventional beams to the treatment room isocenter. Material &…

The inference phase of deep neural networks (DNNs) in embedded systems is increasingly vulnerable to fault attacks and failures, which can result in incorrect predictions. These vulnerabilities can potentially lead to catastrophic…

密码学与安全 · 计算机科学 2026-03-20 Kasra Ahmadi , Saeed Aghapour , Mehran Mozaffari Kermani , Reza Azarderakhsh

Recent advances in deep learning have produced highly accurate but increasingly large and complex DNNs, making traditional fault-injection techniques impractical. Accurate fault analysis requires RTL-accurate hardware models. However, this…

硬件体系结构 · 计算机科学 2026-02-03 Rafael Billig Tonetto , Marcello Traiola , Fernando Fernandes dos Santos , Angeliki Kritikakou
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