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Personalized treatment of patients based on tissue-specific cancer subtypes has strongly increased the efficacy of the chosen therapies. Even though the amount of data measured for cancer patients has increased over the last years, most…

机器学习 · 统计学 2017-09-18 Nora K. Speicher , Nico Pfeifer

Time-to-event endpoints show an increasing popularity in phase II cancer trials. The standard statistical tool for such one-armed survival trials is the one-sample log-rank test. Its distributional properties are commonly derived in the…

统计方法学 · 统计学 2026-03-02 Moritz Fabian Danzer , Andreas Faldum , Rene Schmidt

Clustering analysis of daily load profiles represents an effective technique to classify and aggregate electric users based on their actual consumption patterns. Among other purposes, it may be exploited as a preliminary stage for load…

系统与控制 · 电气工程与系统科学 2022-05-11 Francesca Soldan , Alberto Maldarella , Gabriele Paludetto , Enea Bionda , Federico Belloni , Samuele Grillo

Numerous publications have now addressed the principles of designing, analyzing, and reporting the results of, stepped-wedge cluster randomized trials. In contrast, there is little research available pertaining to the design and analysis of…

统计方法学 · 统计学 2018-06-29 Michael Grayling , Adrian Mander , James Wason

Comparing clusterings is central to evaluating unsupervised models, yet the many existing similarity measures can produce widely divergent, sometimes contradictory, evaluations. Clustering similarity measures are typically organized into…

机器学习 · 统计学 2025-11-06 Alexander J. Gates

Mixture Markov Model (MMM) is a widely used tool to cluster sequences of events coming from a finite state-space. However the MMM likelihood being multi-modal, the challenge remains in its maximization. Although Expectation-Maximization…

最优化与控制 · 数学 2026-04-16 Priyam Das , Deborshee Sen , Debsurya De , Jue Hou , Zahra S. H. Abad , Nicole Kim , Zongqi Xia , Tianxi Cai

Principal Component Analysis (PCA) and K-means constitute fundamental techniques in multivariate analysis. Although they are frequently applied independently or sequentially to cluster observations, the relationship between them, especially…

机器学习 · 统计学 2025-12-02 Victor Saquicela , Kenneth Palacio-Baus , Mario Chifla

This letter investigates joint power control and user clustering for downlink non-orthogonal multiple access systems. Our aim is to minimize the total power consumption by taking into account not only the conventional transmission power but…

信息论 · 计算机科学 2018-05-09 Zhaohui Yang , Cunhua Pan , Wei Xu , Ming Chen

A platform trial with a master protocol provides an infrastructure to ethically and efficiently evaluate multiple treatment options in multiple diseases. Given that certain study drugs can enter or exit a platform trial, the randomization…

统计方法学 · 统计学 2025-07-15 Tianyu Zhan , Jane Zhang , Lei Shu , Yihua Gu

Complete randomization balances covariates on average, but covariate imbalance often exists in finite samples. Rerandomization can ensure covariate balance in the realized experiment by discarding the undesired treatment assignments. Many…

统计方法学 · 统计学 2022-07-07 Xin Lu , Tianle Liu , Hanzhong Liu , Peng Ding

Modern high-dimensional methods often adopt the "bet on sparsity" principle, while in supervised multivariate learning statisticians may face "dense" problems with a large number of nonzero coefficients. This paper proposes a novel…

机器学习 · 统计学 2022-02-10 Yiyuan She , Jiahui Shen , Chao Zhang

What proportion of treated units actually benefited from an experimental intervention? What is the median or the largest individual treatment effect? This paper develops methods for answering such questions about the distribution of…

统计方法学 · 统计学 2026-05-11 David Kim , Yongchang Su , Jake Bowers , Xinran Li

Causal inference analyses often use existing observational data, which in many cases has some clustering of individuals. In this paper we discuss propensity score weighting methods in a multilevel setting where within clusters individuals…

应用统计 · 统计学 2020-12-24 Youjin Lee , Trang Q. Nguyen , Elizabeth A. Stuart

As in other estimation scenarios, likelihood based estimation in the normal mixture set-up is highly non-robust against model misspecification and presence of outliers (apart from being an ill-posed optimization problem). A robust…

统计方法学 · 统计学 2023-12-20 Soumya Chakraborty , Ayanendranath Basu , Abhik Ghosh

The micro-randomized trial (MRT) is a sequential randomized experimental design to empirically evaluate the effectiveness of mobile health (mHealth) intervention components that may be delivered at hundreds or thousands of decision points.…

统计方法学 · 统计学 2021-12-14 Jieru Shi , Zhenke Wu , Walter Dempsey

Clustering analysis is one of the most widely used statistical tools in many emerging areas such as microarray data analysis. For microarray and other high-dimensional data, the presence of many noise variables may mask underlying…

机器学习 · 统计学 2008-03-26 Benhuai Xie , Wei Pan , Xiaotong Shen

Kernel power $k$-means (KPKM) leverages a family of means to mitigate local minima issues in kernel $k$-means. However, KPKM faces two key limitations: (1) the computational burden of the full kernel matrix restricts its use on extensive…

机器学习 · 计算机科学 2025-11-14 Yixi Chen , Weixuan Liang , Tianrui Liu , Jun-Jie Huang , Ao Li , Xueling Zhu , Xinwang Liu

We introduce a novel class of factor analysis methodologies for the joint analysis of multiple studies. The goal is to separately identify and estimate 1) common factors shared across multiple studies, and 2) study-specific factors. We…

应用统计 · 统计学 2018-06-27 Roberta De Vito , Ruggero Bellio , Lorenzo Trippa , Giovanni Parmigiani

It is known that reinforcement learning (RL) is data-hungry. To improve sample-efficiency of RL, it has been proposed that the learning algorithm utilize data from 'approximately similar' processes. However, since the process models are…

机器学习 · 计算机科学 2025-11-24 Vinay Kanakeri , Shivam Bajaj , Ashwin Verma , Vijay Gupta , Aritra Mitra

Cauchy combination test has been widely used for combining correlated p-values, but it may fail to work under certain scenarios. We propose a truncated Cauchy combination test (TCCT) which focus on combining p-values with arbitrary…

统计方法学 · 统计学 2025-06-17 Bo Chen , Wei Xu , Xin Gao
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