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The chemRIXS instrument at the Linac Coherent Light Source offers new opportunities for studying solution-phase systems with time-resolved soft X-ray spectroscopy through the recently commissioned high-repetition-rate LCLS-II X-ray free…

Raman sensing and Raman microscopy are amongst the most specific optical technologies to identify the chemical compounds of unknown samples, and to enable label-free biomedical imaging with molecular contrast. However, the high cost and…

光学 · 物理学 2015-06-16 Sebastian Karpf , Matthias Eibl , Wolfgang Wieser , Thomas Klein , Robert Huber

Raman scattering, an inelastic scattering mechanism, provides information about molecular excitation energies and can be used to identify chemical compounds. Albeit being a powerful analysis tool, especially for label-free biomedical…

光学 · 物理学 2018-10-12 Sebastian Karpf , Matthias Eibl , Wolfgang Wieser , Thomas Klein , Robert Huber

We describe the Phase-Contrast Imaging instrument at the Matter in Extreme Conditions (MEC) endstation of the Linac Coherent Light Source. The instrument can image phenomena with a spatial resolution of a few hundreds of nanometers and at…

The Linac Coherent Light Source (LCLS) is the world's first x-ray free electron laser. It is a scientific user facility operated by the SLAC National Accelerator Laboratory, at Stanford, for the U.S. Department of Energy. As beam time at…

人机交互 · 计算机科学 2024-12-19 Jonathan Segal , Wan-Lin Hu , Paul H. Fuoss , Frank E. Ritter , Jeff Shrager

Advancing temporal resolution in computation, signal modulation, and measurement is crucial for pushing the frontiers of modern science and technology. Optical resonators have recently demonstrated computational operations at frequencies…

光学 · 物理学 2025-10-31 Asaf Farhi

In the last ten years the use of proton beams in radiation therapy has become a clinical tool for treatment of deep-seated tumours. LIBO is a RF compact and low cost proton linear accelerator (SCL type) for hadrontherapy. It is conceived by…

加速器物理 · 物理学 2009-09-29 Paolo Berra

The Linac Coherent Light Source (LCLS) is the first x-ray laser user facility based upon a free electron laser (FEL). In addition to many other stringent requirements, the LCLS XFEL requires extraordinary beam quality to saturate at 1.5…

Programmable spatiotemporal control of light is crucial for advancements in optical communications, imaging, and quantum technologies. Commercial spatial light modulators (SLMs) typically have megapixel-scale apertures but are limited to…

We describe a fast closed-loop optimization wavefront shaping system able to focus light through dynamic scattering media. A MEMS-based spatial light modulator (SLM), a fast photodetector and FPGA electronics are combined to implement a…

仪器与探测器 · 物理学 2018-02-14 Baptiste Blochet , Laurent Bourdieu , Sylvain Gigan

We present a multimodal non-linear optical (NLO) laser-scanning microscope, based on a compact fiber-format excitation laser and integrating coherent anti-Stokes Raman scattering (CARS), stimulated Raman scattering (SRS) and…

We demonstrate a versatile technique for generating continuously wavelength-tunable laser waveforms, with mJ pulse energies and ultrashort pulse durations down to few-cycle in the ultraviolet C and visible spectral ranges. Using the…

Rapid and programmable shaping of light fields is central to modern microscopy, display technologies, optical communications and sensing, quantum engineering, and quantum information processing. Current wavefront shaping technologies face a…

量子物理 · 物理学 2026-01-15 Xin Wei , Zeyang Li , Abhishek V. Karve , Adam L. Shaw , David I. Schuster , Jonathan Simon

Active wavefront control in high-power laser illumination systems is important for technologies such as additive manufacturing, free-space laser communication, and power transmission. Conventional spatial light modulators (SLMs) and…

The hard X-ray instruments at the Linac Coherent Light Source are in the design phase for upgrades that will take full advantage of the high repetition rates that will become available with LCLS-II-HE. The current X-ray Correlation…

加速器物理 · 物理学 2023-08-16 Aashwin Mishra , Nicholas Brennan , Tianyu Huang , Jason Jaquith , Hasan Yavas , Matthew Seaberg

We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and…

生物大分子 · 定量生物学 2015-06-24 Zhaokun Zhou , Helen Miller , Adam J. M. Wollman , Mark C. Leake

We present the development of a versatile apparatus for a 6.2 eV laser-based time and angle-resolved photoemission spectroscopy with micrometer spatial resolution (time-resolved $\mu$-ARPES). With a combination of tunable spatial resolution…

Manipulating the atomic and electronic structure of matter with strong terahertz (THz) fields while probing the response with ultrafast pulses at x-ray free electron lasers (FELs) has offered unique insights into a multitude of physical…

Multi-object astronomical adaptive-optics (MOAO) is now a mature wide-field observation mode to enlarge the adaptive-optics-corrected field in a few specific locations over tens of arc-minutes. The work-scope provided by open-loop…

天体物理仪器与方法 · 物理学 2023-07-19 Carlos M. Correia , Kate Jackson , Jean-Pierre Veran , David Andersen , Olivier Lardiere , Colin Bradley

We present a flexible and efficient ultrafast time-resolved spontaneous Raman spectroscopy setup to study collective excitation and quasi-particle dynamics in quantum matter. The setup has a broad energy tuning range extending from the…

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