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Motile nanosized particles, or "nanobots", promise more effective and less toxic targeted drug delivery because of their unique scale and precision. We consider the case in which the cancer is "diffuse", dispersed such that there are…

多智能体系统 · 计算机科学 2025-09-09 Noble Harasha , Nancy Lynch

Nanorobots are a promising development in targeted drug delivery and the treatment of neurological disorders, with potential for crossing the blood-brain barrier (BBB). These small devices leverage advancements in nanotechnology and…

机器人学 · 计算机科学 2024-11-05 Shahab Kavousinejad

Deploying motile nanosized particles, also known as ``nanobots'', in the human body promises to improve selectivity in drug delivery and reduce side effects. We consider a swarm of nanobots locating a single cancerous region and treating it…

多智能体系统 · 计算机科学 2025-07-17 Noble Harasha , Cristina Gava , Nancy Lynch , Claudia Contini , Frederik Mallmann-Trenn

Despite all the advances achieved in the field of tumor-biology research, in most cases conventional therapies including chemotherapy are still the leading choices. The main disadvantage of these treatments, in addition to the low…

We present the EVONANO platform for the evolution of nanomedicines with application to anti-cancer treatments. EVONANO includes a simulator to grow tumours, extract representative scenarios, and then simulate nanoparticle transport through…

Colorectal cancer (CRC) continues to be a significant global health burden, prompting the need for more effective and targeted therapeutic strategies. Nanoparticle-based drug delivery systems have emerged as a promising approach to address…

其他定量生物学 · 定量生物学 2024-09-10 Mahadi Hasan , Camryn Grace Evett , Jack Burton

Early detection of cancer is essential for timely diagnosis and improved patient outcomes. Among emerging technologies, intra-body nanoscale communication offers an innovative solution to identify molecular cues within the human…

新兴技术 · 计算机科学 2026-03-12 Abdollah Rezagholi , Sergi Abadal , Filip Lemic , Eduard Alarcon , Ethungshan Shitiri

The combination of cytotoxic therapies and anti-angiogenic agents is emerging as a most promising strategy in the treatment of malignant tumors. However, the timing and sequencing of these treatments seem to play essential roles in…

组织与器官 · 定量生物学 2011-06-13 M. Kohandel , C. A. Haselwandter , M. Kardar , S. Sengupta , S. Sivaloganathan

The problem of chemotherapy treatment optimization can be defined in order to minimize the size of the tumor without endangering the patient's health; therefore, chemotherapy requires to achieve a number of objectives, simultaneously. For…

神经与进化计算 · 计算机科学 2023-03-21 Mina Jafari , Behnam Ghavami , Vahid Sattari Naeini

A network of nanomachines (NMs) can be used to build a target detection system for a variety of promising applications. They have the potential to detect toxic chemicals, infectious bacteria, and biomarkers of dangerous diseases such as…

信息论 · 计算机科学 2024-01-10 Nithin V. Sabu , Abhishek K. Gupta

While the use of combination therapy is increasing in prevalence for cancer treatment, it is often difficult to predict the exact interactions between different treatment forms, and their synergistic/antagonistic effects on patient health…

最优化与控制 · 数学 2021-01-29 Jayanth Pratap

The aim is to create a method for accurately estimating the duration of post-cancer treatment, particularly focused on chemotherapy, to optimize patient care and recovery. This initiative seeks to improve the effectiveness of cancer…

计算机与社会 · 计算机科学 2025-04-24 Joyee Chakraborty , Mazahrul Islam Tohin , Danbir Rashid , Tanjil Ahmed Tanmoy , Md. Jehadul Islam Mony

We propose a new framework of computing-inspired multifocal cancer detection procedure (MCDP). Under the rubric of MCDP, the tumor foci to be detected are regarded as solutions of the objective function, the tissue region around the cancer…

组织与器官 · 定量生物学 2019-01-01 Shaolong Shi , Yifan Chen , Xin Yao

Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

计算工程、金融与科学 · 计算机科学 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ha Anh Vu

This paper considers the scenario of a targeted drug delivery system, which consists of deploying a number of biological nanomachines close to a biological target (e.g. a tumor), able to deliver drug molecules in the diseased area. Suitably…

新兴技术 · 计算机科学 2018-08-14 Mauro Femminella , Gianluca Reali , Athanasios V. Vasilakos

Artificial intelligence and machine learning paves the way to achieve greater technical feats. In this endeavor to hone these techniques, quantum machine learning is budding to serve as an important tool. Using the techniques of deep…

Due to the heavy burden on medical institutes and computer-aided image diagnostics (CAD) have been gaining importance in diagnostic medicine to aid the medical staff to attain better service for the patients. Breast cancer is a fatal…

定量方法 · 定量生物学 2023-03-24 Musaddiq Al Ali , Amjad Y. Sahib , Muazez Al Ali

Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…

定量方法 · 定量生物学 2020-08-20 SeyedMehdi Abtahi , Mojtaba Sharifi

Cancer treatment outcomes are influenced not only by clinical and demographic factors but also by the collaboration of healthcare teams. However, prior work has largely overlooked the potential role of human collaboration in shaping patient…

社会与信息网络 · 计算机科学 2025-12-04 Hsiao-Ying Lu , Kwan-Liu Ma
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